Molecular genetic characterization and haplotype diversity of swine leukocyte antigen in Chinese Rongshui miniature pigs

2019 ◽  
Vol 112 ◽  
pp. 215-222
Author(s):  
Caixia Gao ◽  
Chang Xin ◽  
Xiuying Wang ◽  
Jinqiang Quan ◽  
Changwen Li ◽  
...  
2002 ◽  
Vol 184 (22) ◽  
pp. 6130-6137 ◽  
Author(s):  
Shara Allen ◽  
Julie L. Zilles ◽  
Diana M. Downs

ABSTRACT Together, the biosyntheses of histidine, purines, and thiamine pyrophosphate (TPP) contain examples of convergent, divergent, and regulatory pathway integration. Mutations in two purine biosynthetic genes (purI and purH) affect TPP biosynthesis due to flux through the purine and histidine pathways. The molecular genetic characterization of purI mutants and their respective pseudorevertants resulted in the conclusion that <1% of the wild-type activity of the PurI enzyme was sufficient for thiamine but not for purine synthesis. The respective pseudorevertants were found to be informational suppressors. In addition, it was shown that accumulation of the purine intermediate aminoimidazole carboxamide ribotide inhibits thiamine synthesis, specifically affecting the conversion of aminoimidazole ribotide to hydroxymethyl pyrimidine.


2016 ◽  
Vol 161 (5) ◽  
pp. 1261-1271 ◽  
Author(s):  
Surachet Benjathummarak ◽  
Chanon Fa-ngoen ◽  
Chonlatip Pipattanaboon ◽  
Khwanchit Boonha ◽  
Pongrama Ramasoota ◽  
...  

2006 ◽  
Vol 114 (1) ◽  
pp. 21-30 ◽  
Author(s):  
E. S. Lagudah ◽  
H. McFadden ◽  
R. P. Singh ◽  
J. Huerta-Espino ◽  
H. S. Bariana ◽  
...  

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