Evaluation in vitro and in vivo of biomimetic hydroxyapatite coated on titanium dental implants

2004 ◽  
Vol 24 (5) ◽  
pp. 647-651 ◽  
Author(s):  
E.C.S. Rigo ◽  
A.O. Boschi ◽  
M. Yoshimoto ◽  
S. Allegrini ◽  
B. Konig ◽  
...  
Keyword(s):  
Dental Implants ◽  
Biomimetic Hydroxyapatite ◽  
Titanium Dental Implants

scholarly journals Defining surfaces : Implant topography – a review (Preprint)

2018 ◽  
Author(s):  
Preeti Satheesh Kumar ◽  
Vyoma Venkatesh Grandhi ◽  
Vrinda Gupta
Keyword(s):  
Surface Roughness ◽  
Surface Topography ◽  
Dental Implants ◽  
Sol Gel ◽  
Implant Surface ◽  
Research Publications ◽  
Bone To Implant Contact ◽  
Titanium Dental Implants

BACKGROUND . A variety of claims are made regarding the effects of surface topography on implant osseointegration. The development of implant surfaces topography has been empirical, requiring numerous in vitro and in vivo tests. Most of these tests were not standardized, using different surfaces, cell populations or animal models. The exact role of surface chemistry and topography on the early events of the osseointegration of dental implants remain poorly understood. OBJECTIVE This review considers the major claims made concerning the effects of titanium implant surface topography on osseointegration. The osseointegration rate of titanium dental implants is related to their composition and surface roughness. The different methods used for increasing surface roughness or applying osteoconductive coatings to titanium dental implants are reviewed. Important findings of consensus are highlighted, and existing controversies are revealed. METHODS This review considers many of the research publications listed in MEDLINE and presented in biomedical research publications and textbooks. Surface treatments, such as titanium plasma-spraying, grit-blasting acid-etching,alkaline etching, anodization,polymer demixing ,sol gel conversion and their corresponding surface morphologies and properties are described. RESULTS Many in vitro evaluations are not predictive of or correlated with in vivo outcomes. In some culture models, increased surface topography positively affects pro-osteogenic cellular activities. Many studies reveal increase in bone-to-implant contact,with increased surface topography modifications on implant surfaces. CONCLUSIONS Increased implant surface topography improves the bone-to-implant contact and the mechanical properties of the enhanced interface.

Influence of acid-etching after grit-blasted on osseointegration of titanium dental implants: in vitro and in vivo studies

2013 ◽  
Vol 24 (8) ◽  
pp. 2047-2055 ◽  
Author(s):  
M. Herrero-Climent ◽  
P. Lázaro ◽  
J. Vicente Rios ◽  
S. Lluch ◽  
M. Marqués ◽  
...  
Keyword(s):  
Dental Implants ◽  
In Vivo Studies ◽  
Acid Etching ◽  
Titanium Dental Implants

scholarly journals Comparison of irrigation protocols for the internal decontamination of dental implants – results of in‐vitro and in‐vivo studies

2021 ◽  
Author(s):  
Pia‐Merete Jervøe‐Storm ◽  
Alexandra Selina Hablützel ◽  
Philipp Bartels ◽  
Dominik Kraus ◽  
Søren Jepsen ◽  
...  
Keyword(s):  
Dental Implants ◽  
In Vivo Studies

Zirconia Biocompatibility in Animal Studies - A Systematic Review

2017 ◽  
Vol 376 ◽  
pp. 12-28 ◽  
Author(s):  
Sanda Mihaela Popescu ◽  
Horia Octavian Manolea ◽  
Oana Andreea Diaconu ◽  
Veronica Mercuţ ◽  
Monica Scrieciu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Implants ◽  
Animal Studies ◽  
Case Reports ◽  
Powder Injection ◽  
Mesh Terms ◽  
Meta Analyses ◽  
Abstract Screening

Zirconia is a metal used in dental implantology. Its biocompatibility was studied in vitro and in vivo, results of the studies being analyzed in reviews and meta analyses. The aim of this systematic review was to evaluate biocompatibility of zirconia in animal studies in vivo expressed as results of histomorphometric tests. Databases were searched from 1980 until February 2016, with different combination of the following MeSH terms: zirconium, biocompatibility, dental implants, in vivo, animal studies. Letters to the editors, case reports, commentaries, review articles and articles published in other languages then English were excluded. The search of PubMed, ScienceDirect and Google Scholar databases yielded 690 titles. After abstract screening and duplicate discarding 50 articles were identified and finally, 40 were included in the review. Most of the studies compared zirconia with titanium, a well established material for dental implants. In majority of the studies zirconia showed a similar osseointegration with titanium. Surface implant treatments, like sandblasted and etched zirconia (ZrO2-SLA), alumina toughed zirconia (ATZ), and powder injection molding (PIM) were used to improve osseointegration of zirconia with good results. In the light of histomorphometric test, zirconia, no matter physical and structural forms tested, is a biocompatible material.

First titanium dental implants with white surfaces: Preparation and in vitro tests

2014 ◽  
Vol 30 (7) ◽  
pp. 759-768 ◽  
Author(s):  
Milena R. Kaluđerović ◽  
Joachim P. Schreckenbach ◽  
Hans-Ludwig Graf
Keyword(s):  
Dental Implants ◽  
In Vitro Tests ◽  
Titanium Dental Implants

A carboxymethyl chitosan and peptide-decorated polyetheretherketone ternary biocomposite with enhanced antibacterial activity and osseointegration as orthopedic/dental implants

2016 ◽  
Vol 4 (10) ◽  
pp. 1878-1890 ◽  
Author(s):  
Anxiu Xu ◽  
Liwei Zhou ◽  
Yi Deng ◽  
Xianshen Chen ◽  
Xiaoling Xiong ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Osteogenic Differentiation ◽  
Dental Implants ◽  
Carboxymethyl Chitosan

A carboxymethyl chitosan and peptide-decorated PEEK ternary biocomposite showed enhanced antibacterial activity, in vitro osteogenic differentiation and in vivo osseointegration.

scholarly journals Direct Metal Laser Sintering Titanium Dental Implants: A Review of the Current Literature

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
F. Mangano ◽  
L. Chambrone ◽  
R. van Noort ◽  
C. Miller ◽  
P. Hatton ◽  
...  
Keyword(s):  
Dental Implants ◽  
Methodological Quality ◽  
Meta Analysis ◽  
Three Dimensional ◽  
Laser Sintering ◽  
Titanium Implants ◽  
Human Studies ◽  
Direct Metal Laser Sintering ◽  
Titanium Dental Implants

Statement of Problem. Direct metal laser sintering (DMLS) is a technology that allows fabrication of complex-shaped objects from powder-based materials, according to a three-dimensional (3D) computer model. With DMLS, it is possible to fabricate titanium dental implants with an inherently porous surface, a key property required of implantation devices.Objective. The aim of this review was to evaluate the evidence for the reliability of DMLS titanium dental implants and their clinical and histologic/histomorphometric outcomes, as well as their mechanical properties.Materials and Methods. Electronic database searches were performed. Inclusion criteria were clinical and radiographic studies, histologic/histomorphometric studies in humans and animals, mechanical evaluations, andin vitrocell culture studies on DMLS titanium implants. Meta-analysis could be performed only for randomized controlled trials (RCTs); to evaluate the methodological quality of observational human studies, the Newcastle-Ottawa scale (NOS) was used.Results. Twenty-seven studies were included in this review. No RCTs were found, and meta-analysis could not be performed. The outcomes of observational human studies were assessed using the NOS: these studies showed medium methodological quality.Conclusions. Several studies have demonstrated the potential for the use of DMLS titanium implants. However, further studies that demonstrate the benefits of DMLS implants over conventional implants are needed.

scholarly journals Nanomodified Peek Dental Implants: Bioactive Composites and Surface Modification—A Review

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Shariq Najeeb ◽  
Zohaib Khurshid ◽  
Jukka Pekka Matinlinna ◽  
Fahad Siddiqui ◽  
Mohammad Zakaria Nassani ◽  
...  
Keyword(s):  
Dental Implants ◽  
Plasma Etching ◽  
Animal Studies ◽  
Relevant Literature ◽  
Melt Blending ◽  
Gas Plasma ◽  
Study Selection ◽  
Bioactive Composites

Purpose. The aim of this review is to summarize and evaluate the relevant literature regarding the different ways how polyetheretherketone (PEEK) can be modified to overcome its limited bioactivity, and thereby making it suitable as a dental implant material.Study Selection. An electronic literature search was conducted via the PubMed and Google Scholar databases using the keywords “PEEK dental implants,” “nano,” “osseointegration,” “surface treatment,” and “modification.” A total of 16in vivoandin vitrostudies were found suitable to be included in this review.Results. There are many viable methods to increase the bioactivity of PEEK. Most methods focus on increasing the surface roughness, increasing the hydrophilicity and coating osseoconductive materials.Conclusion. There are many ways in which PEEK can be modified at a nanometer level to overcome its limited bioactivity. Melt-blending with bioactive nanoparticles can be used to produce bioactive nanocomposites, while spin-coating, gas plasma etching, electron beam, and plasma-ion immersion implantation can be used to modify the surface of PEEK implants in order to make them more bioactive. However, more animal studies are needed before these implants can be deemed suitable to be used as dental implants.

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