One-pot facile synthesis of PEGylated superparamagnetic iron oxide nanoparticles for MRI contrast enhancement

2014 ◽  
Vol 41 ◽  
pp. 161-167 ◽  
Author(s):  
Lingling Dai ◽  
Yongkang Liu ◽  
Zhongqiu Wang ◽  
Fangfang Guo ◽  
Donglu Shi ◽  
...  
2019 ◽  
Vol 290 ◽  
pp. 301-306
Author(s):  
Osama Abu Noqta ◽  
Azlan Abdul Aziz ◽  
Adamu Ibrahim Usman

Superparamagnetic iron oxide nanoparticles (SPION) were synthesized by one pot coprecipitation method at room temperature in the presence of Polyvinylpyrrolidone (PVP). X-ray powder diffraction (XRD), transmission electron microscopy (TEM), and Vibrating Sample Magnetometer (VSM) were used to analysis the physicochemical properties of PVP-SPION. The XRD patterns confirmed that the structure of as-synthesized sample is magnetite with cubic structure system. In TEM results, the image of PVP-SPION displayed that the size of particles was 14.05 nm with narrower size distribution and also the PVP played important role to minimize the agglomeration of SPION. Finally, the high saturation magnetization value of PVP-SPION (53.0 emu/g) indicate the as-synthesized sample has a great potential as a contrast agent for MRI.


2014 ◽  
Vol 38 (9) ◽  
pp. 4344-4350 ◽  
Author(s):  
Elias Mitchell ◽  
Ram K. Gupta ◽  
Kwadwo Mensah-Darkwa ◽  
Dhananjay Kumar ◽  
Karthik Ramasamy ◽  
...  

The TEM image of the synthesized iron oxide nanocrystals.


2015 ◽  
Vol 17 (6) ◽  
pp. 4609-4619 ◽  
Author(s):  
Ansar Ereath Beeran ◽  
Shaiju. S. Nazeer ◽  
Francis Boniface Fernandez ◽  
Krishna Surendra Muvvala ◽  
Wilfried Wunderlich ◽  
...  

Despite the success in the use of superparamagnetic iron oxide nanoparticles (SPION) for various scientific applications, its potential in biomedical fields has not been exploited to its full potential.


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