One-pot synthesis of biocompatible superparamagnetic iron oxide nanoparticles/hydrogel based on salep: Characterization and drug delivery

2014 ◽  
Vol 101 ◽  
pp. 741-751 ◽  
Author(s):  
Ghasem Rezanejade Bardajee ◽  
Zari Hooshyar
Keyword(s):  
Drug Delivery ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
One Pot ◽  
One Pot Synthesis

Synthesis of PVP Coated Superparamagnetic Iron Oxide Nanoparticles with a High Saturation Magnetization

2019 ◽  
Vol 290 ◽  
pp. 301-306
Author(s):  
Osama Abu Noqta ◽  
Azlan Abdul Aziz ◽  
Adamu Ibrahim Usman
Keyword(s):  
Iron Oxide ◽  
Saturation Magnetization ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
High Saturation Magnetization ◽  
One Pot ◽  
High Saturation ◽  
Size Of Particles

Superparamagnetic iron oxide nanoparticles (SPION) were synthesized by one pot coprecipitation method at room temperature in the presence of Polyvinylpyrrolidone (PVP). X-ray powder diffraction (XRD), transmission electron microscopy (TEM), and Vibrating Sample Magnetometer (VSM) were used to analysis the physicochemical properties of PVP-SPION. The XRD patterns confirmed that the structure of as-synthesized sample is magnetite with cubic structure system. In TEM results, the image of PVP-SPION displayed that the size of particles was 14.05 nm with narrower size distribution and also the PVP played important role to minimize the agglomeration of SPION. Finally, the high saturation magnetization value of PVP-SPION (53.0 emu/g) indicate the as-synthesized sample has a great potential as a contrast agent for MRI.

ß-Amido Acid Functionalised Superparamagnetic Iron Oxide Nanoparticles as a Novel Carrier for Efficient Delivery of Doxorubicine

2017 ◽  
Vol 41 (3) ◽  
pp. 129-135
Author(s):  
Fatemeh Ebrahimi ◽  
Maryam Karimi ◽  
Hasan Sereshti ◽  
Mohsen Yousefifar
Keyword(s):  
Electron Microscopy ◽  
Drug Delivery ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Precipitation Method ◽  
Hydrodynamic Diameter ◽  
Oxide Nanoparticles ◽  
Amido Acid

Superparamagnetic iron oxide nanoparticles are increasingly used in medical applications due to their unique physical properties. They are useful carriers for delivering antitumour drugs in targeted cancer treatment. In this study, amido acid-functionalised magnetic nanoparticles (AAFMNs) are used as drug-delivery vehicles for doxorubicine as an efficient tool for the treatment of cancer. Magnetic iron oxide nanoparticles were synthesised using a co-precipitation method. The prepared iron oxide nanoparticles were then functionalised with amido acid functional groups. Finally, the synthesised AAFMNs were used for the delivery of doxorubicine. AAFMNs were characterised by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, thermogravimetric analysis and zeta potential. An in vitro-determined hydrodynamic diameter of ∼80 nm suggested their applicability for this purpose. The findings show that AAFMNs are a promising tool for potential magnetic drug delivery.

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