scholarly journals Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease

2014 ◽  
Vol 70 ◽  
pp. 214-223 ◽  
Author(s):  
Laurie H. Sanders ◽  
Jennifer McCoy ◽  
Xiaoping Hu ◽  
Pier G. Mastroberardino ◽  
Bryan C. Dickinson ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Dna Damage ◽  
Parkinson's Disease ◽  
Mitochondrial Dna ◽  
Molecular Marker ◽  
Mitochondrial Dna Damage

scholarly journals LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson’s disease

2017 ◽  
Vol 26 (22) ◽  
pp. 4340-4351 ◽  
Author(s):  
Evan H Howlett ◽  
Nicholas Jensen ◽  
Frances Belmonte ◽  
Faria Zafar ◽  
Xiaoping Hu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Dna Damage ◽  
Parkinson's Disease ◽  
Mitochondrial Dna ◽  
Mitochondrial Dna Damage ◽  
Lrrk2 G2019s ◽  
Lrrk2 Kinase

scholarly journals LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction

2014 ◽  
Vol 62 ◽  
pp. 381-386 ◽  
Author(s):  
Laurie H. Sanders ◽  
Josée Laganière ◽  
Oliver Cooper ◽  
Sally K. Mak ◽  
B. Joseph Vu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Dna Damage ◽  
Parkinson's Disease ◽  
Mitochondrial Dna ◽  
Neural Cells ◽  
Gene Correction ◽  
Mitochondrial Dna Damage

Lewy body pathology is associated with mitochondrial DNA damage in Parkinson's disease

2013 ◽  
Vol 34 (9) ◽  
pp. 2231-2233 ◽  
Author(s):  
Sarina K. Müller ◽  
Andreas Bender ◽  
Christoph Laub ◽  
Tobias Högen ◽  
Falk Schlaudraff ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Dna Damage ◽  
Parkinson's Disease ◽  
Mitochondrial Dna ◽  
Lewy Body ◽  
Mitochondrial Dna Damage ◽  
Lewy Body Pathology

scholarly journals Neuronal complex I deficiency occurs throughout the Parkinson’s disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage

2017 ◽  
Vol 135 (3) ◽  
pp. 409-425 ◽  
Author(s):  
Irene H. Flønes ◽  
Erika Fernandez-Vizarra ◽  
Maria Lykouri ◽  
Brage Brakedal ◽  
Geir Olve Skeie ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Dna Damage ◽  
Parkinson's Disease ◽  
Mitochondrial Dna ◽  
Complex I ◽  
Mitochondrial Dna Damage ◽  
Complex I Deficiency

Novel mitochondrial DNA mutations in Parkinson's disease

2002 ◽  
Vol 109 (5-6) ◽  
pp. 721-729 ◽  
Author(s):  
G. Richter ◽  
A. Sonnenschein ◽  
T. Grünewald ◽  
H. Reichmann ◽  
B. Janetzky
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Mitochondrial Dna ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations

OGG1 Genetic Polymorphism Is Associated with Mitochondrial DNA Damage in Pesticide-Exposed Fruit Growers

Epidemiology ◽  
2009 ◽  
Vol 20 ◽  
pp. S99
Author(s):  
Ruey-Hong Wong ◽  
Pei-Lin Huang ◽  
Yu-Hsuan Yeh ◽  
Yu-Ching Chen ◽  
Yi-Jie Liu ◽  
...  
Keyword(s):  
Dna Damage ◽  
Mitochondrial Dna ◽  
Genetic Polymorphism ◽  
Mitochondrial Dna Damage

scholarly journals Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with Systemic Lupus Erythematosus

Lupus ◽  
2014 ◽  
Vol 23 (11) ◽  
pp. 1133-1141 ◽  
Author(s):  
L López-López ◽  
M Nieves-Plaza ◽  
M del R Castro ◽  
YM Font ◽  
CA Torres-Ramos ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Dna Damage ◽  
Mitochondrial Dna ◽  
Lupus Erythematosus ◽  
Disease Duration ◽  
Systemic Lupus ◽  
Mitochondrial Dna Damage ◽  
Damage Accrual

A rapid assay for mitochondrial DNA damage and respiratory chain inhibition in the yeastSaccharomyces cerevisiae

2001 ◽  
Vol 38 (2-3) ◽  
pp. 153-158 ◽  
Author(s):  
Barry J. Barclay ◽  
Carrie L. DeHaan ◽  
Ursula G.G. Hennig ◽  
Oksana Iavorovska ◽  
Reid W. von Borstel ◽  
...  
Keyword(s):  
Dna Damage ◽  
Mitochondrial Dna ◽  
Respiratory Chain ◽  
Rapid Assay ◽  
Mitochondrial Dna Damage
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