In vitro antimicrobial activity against Pseudomonas aeruginosa and acute oral toxicity of marine algae Gracilaria changii

2010 ◽  
Vol 27 (4) ◽  
pp. 390-396 ◽  
Author(s):  
Sreenivasan Sasidharan ◽  
Ibrahim Darah ◽  
Mohd Kassim Mohd Jain Noordin
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Marine Algae ◽  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
In Vitro Antimicrobial Activity ◽  
Gracilaria Changii

In vitro antimicrobial activity of LED irradiation on Pseudomonas aeruginosa

2017 ◽  
Vol 168 ◽  
pp. 25-29 ◽  
Author(s):  
Morena Petrini ◽  
Paolo Trentini ◽  
Domenico Tripodi ◽  
Giuseppe Spoto ◽  
Simonetta D'Ercole
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
In Vitro Antimicrobial Activity ◽  
Led Irradiation

scholarly journals Acute, Multiple-Dose Dermal and Genetic Toxicity of Nu-3: A Novel Antimicrobial Agent

2010 ◽  
Vol 2010 ◽  
pp. 1-8
Author(s):  
Juan Sun ◽  
Yanxin Hu ◽  
Shanping Cao ◽  
Guozhong Zhang ◽  
Lun-Quan Sun ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Multiple Dose ◽  
Hematological Parameters ◽  
Acute Oral Toxicity ◽  
Antimicrobial Compound ◽  
Oral Toxicity ◽  
Genetic Toxicity ◽  
Toxicological Profile

Nu-3 [butyl-phosphate--thymidine--phosphate-butyl] is a modified nucleotide that has been shown to have antimicrobial activity against a range of bacteria includingPseudomonas aeruginosa. However, data on the toxicological profile of Nu-3 are still lacking. In the present study, the toxicity of Nu-3 was evaluated by the following studies: acute oral toxicity, dermal and mucous membrane irritation, multiple-dose toxicity and genotoxicity in vivo and vitro. The acute oral toxicity test in mice showed that Nu-3 had an of 2001mg/kg body weight. The irritation tests on rats revealed that Nu-3 was not irritant, with an irritation scoring of 0. The multiple-dose toxicity study in rats showed that Nu-3 did not cause significant changes in histology, selected serum chemistry, and hematological parameters compared to the controls. Rats administrated with multiple-doses of Nu-3 showed no visible toxic symptoms. Both in vitro and in vivo, Nu-3 exhibited no notable genetic toxicity. Overall, the data suggest that Nu-3 is hypotoxic or nontoxic antimicrobial compound that warrants being further developed for treatingPseudomonas aeruginosainfection.

In vitro antimicrobial activity of liposomal meropenem against Pseudomonas aeruginosa strains

2006 ◽  
Vol 315 (1-2) ◽  
pp. 59-66 ◽  
Author(s):  
Zuzanna Drulis-Kawa ◽  
Jerzy Gubernator ◽  
Agata Dorotkiewicz-Jach ◽  
Wlodzimierz Doroszkiewicz ◽  
Arkadiusz Kozubek
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
In Vitro Antimicrobial Activity

scholarly journals Preparation, characterization and in vitro antimicrobial activity of liposomal ceftazidime and cefepime against Pseudomonas aeruginosa strains

2012 ◽  
Vol 43 (3) ◽  
pp. 984-992 ◽  
Author(s):  
Ieda Maria Sapateiro Torres ◽  
Etiene Barbosa Bento ◽  
Larissa da Cunha Almeida ◽  
Luisa Zaiden Carvalho Martins de Sá ◽  
Eliana Martins Lima
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
In Vitro Antimicrobial Activity
Sign in / Sign up

Export Citation Format

Share Document