Expression of spinal cord microRNAs in a rat model of chronic neuropathic pain

2012 ◽  
Vol 506 (2) ◽  
pp. 281-286 ◽  
Author(s):  
Timo Brandenburger ◽  
Mirco Castoldi ◽  
Maike Brendel ◽  
Hilbert Grievink ◽  
Lukas Schlösser ◽  
...  
Pain Practice ◽  
2019 ◽  
Vol 20 (1) ◽  
pp. 75-87 ◽  
Author(s):  
Koen P.V. Meuwissen ◽  
Luuk E. Vries ◽  
Jianwen Wendy Gu ◽  
Tianhe C. Zhang ◽  
Elbert A.J. Joosten

2021 ◽  
Vol LIII (2) ◽  
pp. 94-100
Author(s):  
Olga A. Bondarenko ◽  
Gaspar V. Gavrilov ◽  
Vadim A. Padurets ◽  
Roman V. Kasich

Purpose of the work. The article is devoted to the first experience of epidural stimulation in the Khanty-Mansiysk Autonomous Okrug at the budgetary institution Surgut Clinical Trauma Hospital. Clinical examples are presented for two main indications for the application of this technique (disease of the operated spine, a consequence of spinal cord injury in combination with chronic neuropathic pain syndrome). Research methods. An assessment of the intensity of pain syndrome was given according to a visual analogue scale, the Pain Detect questionnaire; indicators of anxiety, depression on the HADS scale; quality of life according to the Oswestry questionnaire for a follow-up period of 6-12 months in patients with chronic epidural stimulation. Results. A positive assessment of the action during test neurostimulation was 63.3% (38 patients). Of the established permanent systems, a good result was achieved and persisted for 12 months or more in 96% (24 patients). It was necessary to change the stimulation parameters in 13% (3 patients). Revision of permanent systems was performed in 20% (5 patients), due to the progression of the degenerative-dystrophic process of the spine, damage and migration of system elements. Conclusions. Chronic epidural spinal cord stimulation has established itself as a personalized, highly effective, minimally invasive and safe method of treating chronic neuropathic pain syndromes. Multicomponent corrective action is of scientific interest and requires further study.


Stem Cells ◽  
2012 ◽  
Vol 31 (1) ◽  
pp. 83-91 ◽  
Author(s):  
Feng Tao ◽  
Qun Li ◽  
Su Liu ◽  
Haiying Wu ◽  
John Skinner ◽  
...  

2010 ◽  
Vol 1198 (1) ◽  
pp. 168-172 ◽  
Author(s):  
Tera Hasbargen ◽  
Mostafa M. Ahmed ◽  
Gurwattan Miranpuri ◽  
Lin Li ◽  
Kristopher T. Kahle ◽  
...  

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