Corrigendum to Similarities in the patterns of prefrontal cortex activity during spatial and temporal context memory retrieval after equating for task structure and performance [Neuroimage 54/2 (2011) 1549–1564]

Functional magnetic resonance imaging (fMRI) evidence indicates that different subregions of ventrolateral prefrontal cortex (VLPFC) participate in distinct cortical networks. These networks have been shown to support separable cognitive functions: anterior VLPFC [inferior frontal gyrus (IFG) pars orbitalis] functionally correlates with a ventral fronto-temporal network associated with top-down influences on memory retrieval, while mid-VLPFC (IFG pars triangularis) functionally correlates with a dorsal fronto-parietal network associated with postretrieval control processes. However, it is not known to what extent subregional differences in network affiliation and function are driven by differences in the organization of underlying white matter pathways. We used high-angular-resolution diffusion spectrum imaging and functional connectivity analysis in unanesthetized humans to address whether the organization of white matter connectivity differs between subregions of VLPFC. Our results demonstrate a ventral-dorsal division within IFG. Ventral IFG as a whole connects broadly to lateral temporal cortex. Although several different individual white matter tracts form connections between ventral IFG and lateral temporal cortex, functional connectivity analysis of fMRI data indicates that these are part of the same ventral functional network. By contrast, across subdivisions, dorsal IFG was connected with the midfrontal gyrus and correlated as a separate dorsal functional network. These qualitative differences in white matter organization within larger macroanatomical subregions of VLPFC support prior functional distinctions among these regions observed in task-based and functional connectivity fMRI studies. These results are consistent with the proposal that anatomical connectivity is a crucial determinant of systems-level functional organization of frontal cortex and the brain in general.

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Repeated transcranial magnetic stimulation on dorsolateral prefrontal cortex improves performance in emotional memory retrieval as a function of level of anxiety and stimulus valence

Psychiatry and Clinical Neurosciences ◽

10.1111/pcn.12041 ◽

2013 ◽

Vol 67 (4) ◽

pp. 210-218 ◽

Cited By ~ 17

Author(s):

Michela Balconi ◽

Chiara Ferrari

Keyword(s):

Prefrontal Cortex ◽

Transcranial Magnetic Stimulation ◽

Memory Retrieval ◽

Magnetic Stimulation ◽

Dorsolateral Prefrontal Cortex ◽

Emotional Memory ◽

Dorsolateral Prefrontal ◽

Stimulus Valence

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Frontal Brain Activity during Episodic and Semantic Retrieval: Insights from Event-Related Potentials

Journal of Cognitive Neuroscience ◽

10.1162/089892999563661 ◽

1999 ◽

Vol 11 (6) ◽

pp. 598-609 ◽

Cited By ~ 29

Author(s):

Charan Ranganath ◽

Ken A. Paller

Keyword(s):

Prefrontal Cortex ◽

Memory Retrieval ◽

Brain Activity ◽

Novelty Detection ◽

Event Related Potentials ◽

Episodic Retrieval ◽

Semantic Retrieval ◽

Retrieval Task ◽

Related Potentials ◽

The Right

Previous neuropsychological and neuroimaging results have implicated the prefrontal cortex in memory retrieval, although its precise role is unclear. In the present study, we examined patterns of brain electrical activity during retrieval of episodic and semantic memories. In the episodic retrieval task, participants retrieved autobiographical memories in response to event cues. In the semantic retrieval task, participants generated exemplars in response to category cues. Novel sounds presented intermittently during memory retrieval elicited a series of brain potentials including one identifiable as the P3a potential. Based on prior research linking P3a with novelty detection and with the frontal lobes, we predicted that P3a would be reduced to the extent that novelty detection and memory retrieval interfere with each other. Results during episodic and semantic retrieval tasks were compared to results during a task in which subjects attended to the auditory stimuli. P3a amplitudes were reduced during episodic retrieval, particularly at right lateral frontal scalp locations. A similar but less lateralized pattern of frontal P3a reduction was observed during semantic retrieval. These findings support the notion that the right prefrontal cortex is engaged in the service of memory retrieval, particularly for episodic memories.

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