Microinjections of the dopamine D2 receptor antagonist sulpiride into the medial prefrontal cortex attenuate glucocorticoid-induced impairment of long-term memory retrieval in rats

2007 ◽  
Vol 87 (3) ◽  
pp. 385-390 ◽  
Author(s):  
Roghayeh Pakdel ◽  
Ali Rashidy-Pour
Keyword(s):  
Prefrontal Cortex ◽  
Receptor Antagonist ◽  
Medial Prefrontal Cortex ◽  
Memory Retrieval ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Long Term Memory ◽  
Term Memory ◽  
Dopamine D2 Receptor Antagonist

scholarly journals Hemispheric Asymmetries in Electroencephalogram Oscillations for Long-Term Memory Retrieval in Healthy Individuals

2020 ◽  
Vol 10 (12) ◽  
pp. 937
Author(s):  
Soyiba Jawed ◽  
Hafeez Ullah Amin ◽  
Aamir Saeed Malik ◽  
Ibrahima Faye
Keyword(s):  
Prefrontal Cortex ◽  
Episodic Memory ◽  
Memory Retrieval ◽  
Frontal Region ◽  
Long Term Memory ◽  
Healthy Individuals ◽  
Term Memory ◽  
Delta Band ◽  
The Right

The hemispherical encoding retrieval asymmetry (HERA) model, established in 1991, suggests that the involvement of the right prefrontal cortex (PFC) in the encoding process is less than that of the left PFC. The HERA model was previously validated for episodic memory in subjects with brain traumas or injuries. In this study, a revised HERA model is used to investigate long-term memory retrieval from newly learned video-based content for healthy individuals using electroencephalography. The model was tested for long-term memory retrieval in two retrieval sessions: (1) recent long-term memory (recorded 30 min after learning) and (2) remote long-term memory (recorded two months after learning). The results show that long-term memory retrieval in healthy individuals for the frontal region (theta and delta band) satisfies the revised HERA asymmetry model.

Retroactive interference of object-in-context long-term memory: Role of dorsal hippocampus and medial prefrontal cortex

Hippocampus ◽  
2014 ◽  
Vol 24 (12) ◽  
pp. 1482-1492 ◽  
Author(s):  
María Cecilia Martínez ◽  
María Eugenia Villar ◽  
Fabricio Ballarini ◽  
Haydée Viola
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Retroactive Interference ◽  
Dorsal Hippocampus ◽  
Long Term Memory ◽  
Term Memory

scholarly journals Persistent transcriptional programs are associated with remote memory in diverse cells of the medial prefrontal cortex

2019 ◽  
Author(s):  
Michelle B. Chen ◽  
Xian Jiang ◽  
Stephen R. Quake ◽  
Thomas C. Südhof
Keyword(s):  
Gene Expression ◽  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Short Term Memory ◽  
Memory Storage ◽  
Remote Memory ◽  
Long Term Memory ◽  
Term Memory ◽  
Activity Dependent

AbstractIt is thought that memory is stored in ‘engrams’, a subset of neurons that undergo learning-induced alterations. The role of gene-expression during learning and short-term memory has been studied extensively, but little is known about remote memory that can persist for a lifetime. Using long-term contextual fear memory as a paradigm, an activity-dependent transgenic model for engram-specific labeling, and single-cell transcriptomics we probed the gene-expression landscape underlying remote memory consolidation and recall in the medial prefrontal cortex. Remarkably, we find sustained activity-specific transcriptional alterations in diverse populations of neurons that persist even weeks after fear-learning and are distinct from those previously identified in learning. Out of a vast plasticity-coding space, we uncover select membrane-fusion genes that could play important roles in maintaining remote memory traces. Unexpectedly, astrocytes and microglia also acquire new persistent gene signatures upon recall of remote memory, suggesting that they actively contribute to memory circuits. Our discovery of novel distinct gene-expression programs involved in long term memory adds an important dimension of activity-dependent cellular states to existing brain taxonomy atlases and sheds light on the elusive mechanisms of remote memory storage.

scholarly journals Prefrontal cortex neuronal ensembles encoding fear drive fear expression during long-term memory retrieval

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Giuseppe Giannotti ◽  
Jasper A. Heinsbroek ◽  
Alexander J. Yue ◽  
Karl Deisseroth ◽  
Jamie Peters
Keyword(s):  
Prefrontal Cortex ◽  
Memory Retrieval ◽  
Long Term Memory ◽  
Term Memory ◽  
Neuronal Ensembles ◽  
Fear Expression

Effects of haloperidol, a dopamine D2 receptor antagonist, on feather pecking behaviour in laying hens

2004 ◽  
Vol 86 (1-2) ◽  
pp. 77-91 ◽  
Author(s):  
J.B. Kjaer ◽  
B.M. Hjarvard ◽  
K.H. Jensen ◽  
J. Hansen-Møller ◽  
O. Naesbye Larsen
Keyword(s):  
Receptor Antagonist ◽  
Laying Hens ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Feather Pecking ◽  
Dopamine D2 ◽  
Dopamine D2 Receptor Antagonist

Depressive symptomatology and learning: Does intermediate testing or restudying the information determine long-term memory retrieval of novel symbols?

2016 ◽  
Vol 33 (S1) ◽  
pp. S412-S412
Author(s):  
V. Giannouli
Keyword(s):  
Retention Interval ◽  
Music Education ◽  
Memory Retrieval ◽  
Testing Effect ◽  
Depressive Symptomatology ◽  
Long Term Memory ◽  
Music Notation ◽  
Testing Time ◽  
Term Memory

IntroductionThere is a hypothesis in cognitive psychology that long-term memory retrieval is improved by intermediate testing than by restudying the information. The effect of testing has been investigated with the use of a variety of stimuli. However, almost all testing effect studies to date have used purely verbal materials such as word pairs, facts and prose passages.ObjectiveHere byzantine music symbol–word pairs were used as to-be-learned materials to demonstrate the generalisability of the testing effect to symbol learning in participants with and without depressive symptoms.MethodFifty healthy (24 women, M age = 26.20, SD = 5.64) and forty volunteers with high depressive symptomatology (20 women, M age = 27.00, SD = 1.04) were examined. The participants did not have a music education. The examination material was completely new for them: 16 byzantine music notation stimuli, paired with a verbal label (the ancient Greek name of the symbol). Half of the participants underwent intermediate testing and the others restudied the information in a balanced design.ResultsResults indicated that there were no statistically significant differences in final memory test performance after a retention interval of 5 minutes for both groups of participants with low and high level depressive symptomatology (P > 0.005). After a retention interval of a week, tested pairs were retained better than repeatedly studied pairs for high and low depressive symptomatology groups (P < 0.005).ConclusionsThis research suggests that the effect of testing time on later memory retrieval can also be obtained in byzantine symbol learning.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Sign in / Sign up

Export Citation Format

Share Document