scholarly journals Outcome-selective reinstatement is predominantly context-independent, and associated with c-Fos activation in the posterior dorsomedial striatum

2021 ◽  
pp. 107556
Author(s):  
Arvie R. Abiero ◽  
Zaid Ali ◽  
Bryce Vissel ◽  
Laura A. Bradfield
Keyword(s):  
2021 ◽  
Vol 41 ◽  
pp. 38-44
Author(s):  
Bernard W Balleine ◽  
James Peak ◽  
Miriam Matamales ◽  
Jesus Bertran-Gonzalez ◽  
Genevra Hart

2019 ◽  
Author(s):  
Sebastiano Bariselli ◽  
Nanami Miyazaki ◽  
Alexxai Kravitz

AbstractStimulants are one of the most widely prescribed classes of pharmaceuticals, but it is unclear which brain pathways underlie their therapeutic and adverse actions. Here, with real-time monitoring of circuit plasticity, we demonstrate that psychostimulants strengthen orbitofrontal (OFC) to dorsomedial striatum (DMS) pathway synapses, and increase striatal output in awake mice. In vivo high-frequency stimulation of OFC-DMS pathway blocked stimulant-induced potentiation and the expression of locomotor sensitization, thereby directly linking OFC-DMS plasticity to hyperactivity.


2018 ◽  
Vol 596 (16) ◽  
pp. 3695-3707 ◽  
Author(s):  
Patricia Monteiro ◽  
Boaz Barak ◽  
Yang Zhou ◽  
Rebecca McRae ◽  
Diana Rodrigues ◽  
...  

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