Normal weight obesity is associated with hypercholesterolemia and low muscle mass in persons living with HIV on antiretroviral treatment

Nutrition ◽  
2021 ◽  
pp. 111515
Author(s):  
Ivan A. Osuna-Padilla ◽  
Nadia C. Rodríguez-Moguel ◽  
Adriana Aguilar-Vargas ◽  
Edna Rodríguez-Aguirre ◽  
Olivia Briceño ◽  
...  
2008 ◽  
Vol 24 (2) ◽  
pp. 247-251 ◽  
Author(s):  
Mallory O. Johnson ◽  
Margaret A. Chesney ◽  
Torsten B. Neilands ◽  
Samantha E. Dilworth ◽  
Robert H. Remien ◽  
...  

2002 ◽  
Vol 13 (6) ◽  
pp. 393-398 ◽  
Author(s):  
C Dreezen ◽  
W Schrooten ◽  
I de Mey ◽  
F D Goebel ◽  
N Dedes ◽  
...  

Objective: To identify risk factors for the development of lipodystrophy in HIV infected patients on highly active antiretroviral therapy. Methods: A survey among patients with HIV infection using an anonymous questionnaire was conducted in 10 European countries between December 1998 and December 1999. Nine hundred and four people receiving antiretrovirals, were included in the analyses. Results: 368 (41%) people reported an increase in abdominal girth since commencing current antiretroviral treatment. Breast enlargement was reported by 106 people (12%). Lipoatrophy signs were reported by approximately one-third of the people: 291 (32%) complained about decrease in facial fat and 300 (33%) reported decrease in buttock fat. One hundred and thirty-one (15%) people reported both lipoatrophy signs and an increase in abdominal girth (mixed lipodystrophy syndrome). In multivariate analysis, the development of the mixed lipodystrophy syndrome was associated with a longer use of indinavir (OR=1.03, 95% CI: 1.00–1.06), ritonavir (OR=1.06, 1.02–1.09) and stavudine (OR=1.05, 1.02–1.08) and also with age, a longer duration of HIV seropositivity and an advanced stage of HIV infection. Conclusions: This study suggests that multiple factors are associated with the occurrence of lipodystrophy, including the prolonged use of protease inhibitors.


2014 ◽  
Vol 66 ◽  
pp. S116-S122 ◽  
Author(s):  
Jacob O. Odhiambo ◽  
Timothy A. Kellogg ◽  
Andrea A. Kim ◽  
Lucy Ngʼangʼa ◽  
Irene Mukui ◽  
...  

2018 ◽  
Vol 22 (7) ◽  
pp. 2381-2381
Author(s):  
Sean N. Halpin ◽  
Edwin Clayton Carruth ◽  
Ramona P. Rai ◽  
E. Jennifer Edelman ◽  
David A. Fiellin ◽  
...  

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Meizhen Zhang ◽  
Moritz Schumann ◽  
Tao Huang ◽  
Timo Törmäkangas ◽  
Sulin Cheng

Objective The primary aim of this study was to examine the associations of normal weight obesity with physical fitness in Chinese university students. As a secondary aim, we assessed whether possible differences in physical fitness between students classified as NWO and normal weight non-obese (NWNO) were mediated by skeletal muscles mass. Methods A total of 383 students (205 males and 178 females, aged 18–24 years) from two universities volunteered to participate in this study. Body height and weight were measured by standard procedures and body composition was assessed by a bio-impedance device (InBody 720). NWO was defined by a BMI of 18.5 - 23.9 kg/m2 and a body fat percentage of > 20% and > 30% in male and female students, respectively. Physical fitness was measured using a 10-min intermittent endurance running test (Andersen test), counter movement jumps (CMJ) and a 5 × 5-m shuttle run test (5mSR). The level of leisure time physical activity (PA) was assessed by a questionnaire. Results  13.7% of male and 27.5% of female students were classified as NWO. Compared to NWNO, students classified as NWO showed a significantly poorer performance on the Andersen test (males: 1146 ± 70 m vs. 1046 ± 95 m, females: 968 ± 61 m vs. 907 ± 67m, p < 0.001), CMJ (males: 55.0 ± 7.6 cm vs. 44.9 ± 7.5 cm, females: 39.8 ± 8.0 cm vs. 33.7 ± 5.9 cm, p < 0.001), 5mSR (males: 18.7 ± 1.0 s vs. 20.0 ± 0.9 s, females: 21.1 ± 1.1 s vs. 22.4 ± 1.3 s, p < 0.001), respectively. The lower levels of physical fitness in NWO were partially explained by lower skeletal muscle mass (p < 0.001) both in male and female students Conclusions NWO was associated with poorer physical fitness and the relationship was partially mediated by lower skeletal muscle mass. The study indicated that attention should be paid for the potential hidden health risk in university students with normal body mass index but excessive fat mass


2017 ◽  
Vol 21 (7) ◽  
pp. 1914-1925 ◽  
Author(s):  
Heidi M. Crane ◽  
Mary E. McCaul ◽  
Geetanjali Chander ◽  
Heidi Hutton ◽  
Robin M. Nance ◽  
...  

2017 ◽  
Vol 22 (3) ◽  
pp. 848-852 ◽  
Author(s):  
Sean N. Halpin ◽  
Edwin Clayton Carruth ◽  
Ramona P. Rai ◽  
E. Jennifer Edelman ◽  
David A. Fiellin ◽  
...  

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