Estrogen regulates the expression of retinoic acid synthesis enzymes and binding proteins in mouse skin

2021 ◽  
Author(s):  
Helen B. Everts ◽  
Kathleen A. Silva ◽  
Adriana N. Schmidt ◽  
Susan Opalenikx ◽  
F. Jason Duncan ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Binding Proteins ◽  
Mouse Skin ◽  
Acid Synthesis

scholarly journals Retinoic Acid- and Retinol Binding Proteins in Melanomas and Retinoblastomas

1987 ◽  
Vol 194 (2-3) ◽  
pp. 126-127 ◽  
Author(s):  
F. Daxecker ◽  
G. Daxenbichler ◽  
Ch. Marth
Keyword(s):  
Retinoic Acid ◽  
Binding Proteins

Citral, an inhibitor of retinoic acid synthesis, modifies pattern formation during limb regeneration in the axolotl Ambystoma mexicanum

1999 ◽  
Vol 77 (11) ◽  
pp. 1835-1837 ◽  
Author(s):  
Steven R Scadding
Keyword(s):  
Retinoic Acid ◽  
Pattern Formation ◽  
Limb Regeneration ◽  
Acid Synthesis ◽  
Ambystoma Mexicanum

While the effects of exogenous retinoids on amphibian limb regeneration have been studied extensively, the role of endogenous retinoids is not clear. Hence, I wished to investigate the role of endogenous retinoic acid during axolotl limb regeneration. Citral is a known inhibitor of retinoic acid synthesis. Thus, I treated regenerating limbs of the larval axolotl Ambystoma mexicanum with citral. The result of this inhibition of retinoic acid synthesis was that limb regeneration became extremely irregular and hypomorphic, with serious pattern defects, or was inhibited altogether. I conclude that endogenous retinoic acid plays an important role in pattern formation during limb regeneration.

scholarly journals Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis

Immunity ◽  
2018 ◽  
Vol 49 (6) ◽  
pp. 1103-1115.e6 ◽  
Author(s):  
Mayara Grizotte-Lake ◽  
Guo Zhong ◽  
Kellyanne Duncan ◽  
Jay Kirkwood ◽  
Namrata Iyer ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Epithelial Cell ◽  
Intestinal Epithelial Cell ◽  
Acid Synthesis ◽  
Intestinal Epithelial ◽  
Interleukin 22 ◽  
Microbial Dysbiosis
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