Successful weight loss reduces endothelial activation in individuals with severe obesity participating in a multimodal weight loss program

Author(s):  
Sabine J.M. Sag ◽  
Christina Strack ◽  
Judith Zeller ◽  
Margareta Mohr ◽  
Thomas Loew ◽  
...  
2015 ◽  
Vol 42 (6) ◽  
pp. 769-774 ◽  
Author(s):  
Samantha M. Harden ◽  
Wen You ◽  
Fabio A. Almeida ◽  
Jennie L. Hill ◽  
Laura A. Linnan ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Simona Klemenčič ◽  
Ana Bujišić ◽  
Neža Štiglic Hribernik ◽  
Tadej Battelino ◽  
Matjaž Homan ◽  
...  

Introduction: Adolescent and children obesity is a growing concern worldwide. Bariatric surgery is used as an effective treatment for adolescents with obesity and provides physical and mental health benefits. Application of alternative, minimally invasive, safe, and reversible endoscopic procedures, such as the Duodenojejunal bypass liner (DJBL), has been recently suggested as an effective treatment for adolescents with obesity. We explored specific psychological outcomes of adolescents with obesity during a year of follow-up after undergoing a reversible endoscopic bariatric procedure, and a year after removal. We were also interested in identifying psychological factors that could predict successful weight loss after the procedure.Methods: Nineteen adolescent with severe obesity undergoing DJBL procedure were psychologically assessed in an open-label, prospective clinical trial (NTC0218393), at the implantation of device and at the removal of device after 12 months. Control group of 26 adolescents with severe obesity were recruited from the same outpatient clinic undergoing only conservative treatment. In addition, adolescents from the intervention group were followed for 12 months after the removal of the device. The Youth Self Report (YSR) was used to assess adolescents' emotional and behavioural problems; The Multidimensional Body-Self Relations Questionnaire (MBSRQ) to assess body image and The Eating Disorder Examination Questionnaire (EDE-Q) to assess attitudes and behaviours related to eating disorder.Results: Significant improvements in somatic complain (F = 12.478, p = 0.001), emotional and behavioural problems (F = 7.169, p = 0.011) and food restraining (F = 9.605, p = 0.004) were found in the intervention group at device removal compared to the control group. Moreover, at the time of device removal compared to baseline, improvements in several psychological outcomes were found (F = 32.178 p = 0.000 for emotional and behavioural problems). Adolescents also became more satisfied with their appearance (F = 6.789, p = 0.019). Majority of observed changes remained stable at the next follow up a year after the device removal. Significant predictors of successful weight loss at device removal were fewer overeating episodes (B = 0.147, p = 0.022) and lower body satisfaction (B = 0.932, p = 0.013).Discussion: Following a reversible bariatric procedure, improvements of psychological (emotional and behavioural) factors were found in adolescents with severe obesity. Psychological predictors of successful weight loss were identified, showing the greatest importance of eating behaviour and body satisfaction in successful weight loss.


Author(s):  
Eli Natvik ◽  
Målfrid Råheim ◽  
John Roger Andersen ◽  
Christian Moltu

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S81???S82
Author(s):  
Todd A. Crowder ◽  
Kelli J. Kidd ◽  
C. Michael Buckley ◽  
Mark H. Smith

2021 ◽  
Author(s):  
Enzamaria Fidilio ◽  
Marta Comas ◽  
Miguel Giribés ◽  
Guillermo Cárdenas ◽  
Ramón Vilallonga ◽  
...  

Abstract Purpose One major determinant of weight loss is resting energy expenditure (REE). However, data regarding REE is scarce in patients with severe obesity (SO)—BMI>50kg/m2. Most studies used equation in order to estimate REE and not indirect calorimetry (IC) (gold standard). Additionally, there is no reliable data on the impact of bariatric surgery (BS) on REE. Objectives (a) To evaluate the REE in patients with SO; (b) to compare REE measured by IC (mREE) to that calculated by Mifflin St-Jeor equation (eREE); (c) to evaluate the impact of BS on REE and the relationship with evolution post-BS. Material and Methods Single-center observational study including consecutive patients with SO between January 2010 and December 2015, candidates for BS. mREE was determined at baseline, and 1 and 12 months post-BS by IC, using a Vmax metabolic monitor. Results Thirty-nine patients were included: mean age 46.5±11.77 years, 64.1%women. Preoperative mREE was 2320.38±750.81 kcal/day. One month post-BS, the mREE significantly decreased (1537.6 ± 117.46 kcal/day, p = 0.023) and remained unchanged at 12 months (1526.00 ± 123.35 kcal/day; p =0.682). Reduction in mREE after the BS was a predictor of reaching successful weight loss (nadir) and weight regain (5 years follow-up) (AUCROC of 0.841 (95%CI [0.655–0.909], p=0.032) and AUCROC of 0.855 (95% CI [0.639–0.901]), p= 0.027, respectively). eREE was not valid to identify these changes. Conclusion In patients with SO, a significant reduction of mREE occurs 1 month post-BS, unchanged at 12 months, representing the major conditioning of successful weight loss and maintenance post-BS. Graphical abstract


2010 ◽  
Vol 28 (15_suppl) ◽  
pp. 1522-1522 ◽  
Author(s):  
C. J. Fabian ◽  
J. R. Klemp ◽  
B. F. Kimler ◽  
S. Aversman ◽  
T. A. Phillips ◽  
...  

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S81-S82
Author(s):  
Todd A. Crowder ◽  
Kelli J. Kidd ◽  
C. Michael Buckley ◽  
Mark H. Smith

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