Detection of Helicobacter Pylori in the Middle Ear Fluid of Patients with Otitis Media with Effusion
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OBJECTIVES: In patients with otitis media with effusion (OME), colonization of the middle ear effusion (MEE) by Helicobacter pylori (HP) was investigated. STUDY DESIGN: A prospective nonrandomized study with nonpaired, nonmatched controls. Smear preparations were immunostained with anti-HP antibody and were subjected to Gram staining and Giemsa staining. The rapid urease test (CLO) was done. RESULTS: Twelve of 15 smears for MEE were positive for HP by immunohistochemistry and 14 by Giemsa that were Gram-negative. In 3 with positive immunohistochemistry, the CLO was positive. CONCLUSION: The results suggest that HP may exist in the MEE of some patients with OME.
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1986 ◽
Vol 100
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pp. 1347-1350
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1992 ◽
Vol 102
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pp. 1037???1042
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2003 ◽
Vol 123
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pp. 383-387
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2016 ◽
Vol 7
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pp. 17-22
1997 ◽
Vol 16
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pp. 816-817
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