Prognostic significance and biopsy characteristics of prostate cancer with seminal vesicle invasion on radical prostatectomy: a nationwide population-based study

Pathology ◽  
2017 ◽  
Vol 49 (7) ◽  
pp. 715-720 ◽  
Author(s):  
Anna Kristiansen ◽  
Linda Drevin ◽  
Brett Delahunt ◽  
Hemamali Samaratunga ◽  
David Robinson ◽  
...  
2013 ◽  
Vol 62 (7) ◽  
pp. 1049-1056 ◽  
Author(s):  
Anna Kristiansen ◽  
Fredrik Wiklund ◽  
Peter Wiklund ◽  
Lars Egevad

1998 ◽  
Vol 33 (3) ◽  
pp. 271-277 ◽  
Author(s):  
Bertrand Debras ◽  
Bertrand Guillonneau ◽  
Joelle Bougaran ◽  
Emmanuel Chambon ◽  
Guy Vallancien

2013 ◽  
Vol 113 (4) ◽  
pp. 541-547 ◽  
Author(s):  
Martin Andreas Røder ◽  
Klaus Brasso ◽  
Ib Jarle Christensen ◽  
Jørgen Johansen ◽  
Niels Christian Langkilde ◽  
...  

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e16553-e16553
Author(s):  
Grace L. Lu-Yao ◽  
Jianming He ◽  
Veda N. Giri ◽  
Ann Klassen

e16553 Background: This population-based study assesses the relationship between insurance status and patterns of prostate cancer diagnosis and treatment among men under age 65. Methods: Using the Surveillance, Epidemiology, and End Results (SEER) database, we identified 114,871 prostate cancer patients who were diagnosed before 65 between January 2007 and December 2013. Insurance type was classified as uninsured (3.1%), Medicaid (5.1%) and other including private insurance and coverage from the military or Veterans Affairs (91.8%). We used logistic regression model to quantify the relative risk of being diagnosed with metastasis or regional disease, and the relative likelihood of receiving radical prostatectomy or radiotherapy among those with localized cancer adjusted by, age, race, marital status, region, and diagnosis period. Results: Medicaid or uninsured patients are more likely to have late diagnosis (diagnosed with positive lymph node or metastasis) than patients with non-Medicaid insurance (Table 1). Among men diagnosed with localized prostate cancer, Medicaid and uninsured patients are less likely to receive prostatectomy. Medicaid patients are more likely to have radiotherapy than un-insured (see table). Conclusions: Compared with patients with non-Medicaid insurance, Medicaid and uninsured patients are more likely have late diagnosis and less likely to have radical prostatectomy for localized cancer, after accounting for differences in age, race, marital status, region, and diagnosis period. [Table: see text]


2016 ◽  
Vol 15 (3) ◽  
pp. e167
Author(s):  
D. Robinson ◽  
H. Garmo ◽  
I. Franck Lissbrant ◽  
P. Nilsson ◽  
A. Widmark ◽  
...  

2015 ◽  
Vol 9 (2) ◽  
pp. 67-72 ◽  
Author(s):  
Junya Furukawa ◽  
Hideaki Miyake ◽  
Taka-aki Inoue ◽  
Takayoshi Ogawa ◽  
Hirokazu Tanaka ◽  
...  

Background: The objective of this study was to review our experience with radical prostatectomy (RP) as monotherapy for men with high-risk prostate cancer (PCa). Patients and Methods: This study included 382 consecutive patients who were diagnosed with high-risk PCa according to the D'Amico definition and subsequently underwent RP without neoadjuvant therapy. Biochemical recurrence (BR) was defined as a serum prostate-specific antigen (PSA) level ≥ 0.2 ng/ml on two consecutive measurements, and none of the patients received any adjuvant therapies until their serum PSA levels reached ≥ 0.4 ng/ml. Results: The median preoperative serum PSA level in these 382 patients was 15.9 ng/ml. Pathological stages ≥ pT2c and Gleason scores ≥ 8 were observed in 288 and 194 patients, respectively. During the observation period (median, 48.0 months), BR occurred in 134 patients, and the 5-year BR-free survival rate was 60.1%; however, no patient died of cancer progression. Multivariate analysis identified capsular invasion, seminal vesicle invasion, and surgical margin status as independent predictors of BR. Conclusions: Comparatively favorable cancer control could be achieved using RP as monotherapy for men with high-risk PCa; however, RP alone may be insufficient for patients with capsular invasion, seminal vesicle invasion, and/or surgical margin positivity.


Sign in / Sign up

Export Citation Format

Share Document