scholarly journals Markers of abuse liability of short- vs long-acting opioids in chronic pain patients: A randomized cross-over trial

2009 ◽  
Vol 94 (1) ◽  
pp. 98-107 ◽  
Author(s):  
Barth L. Wilsey ◽  
Scott Fishman ◽  
Chin-Shang Li ◽  
Jeanna Storment ◽  
Anthony Albanese
2019 ◽  
Vol 132 (1) ◽  
pp. 44-51 ◽  
Author(s):  
Paul M. Coplan ◽  
M. Soledad Cepeda ◽  
Kenneth R. Petronis ◽  
Angela DeVeaugh-Geiss ◽  
Alexandra I. Barsdorf ◽  
...  

2005 ◽  
Vol 16 (4) ◽  
pp. 235-242 ◽  
Author(s):  
Astrid von Bueren Jarchow ◽  
Bogdan P. Radanov ◽  
Lutz Jäncke

Abstract: The aim of the present study was to examine to what extent chronic pain has an impact on various attentional processes. To measure these attention processes a set of experimental standard tests of the “Testbatterie zur Aufmerksamkeitsprüfung” (TAP), a neuropsychological battery testing different levels of attention, were used: alertness, divided attention, covert attention, vigilance, visual search, and Go-NoGo tasks. 24 chronic outpatients and 24 well-matched healthy control subjects were tested. The control subjects were matched for age, gender, and education. The group of chronic pain patients exhibited marked deficiencies in all attentional functions except for the divided attention task. Thus, the data supports the notion that chronic pain negatively influences attention because pain patients` attention is strongly captivated by the internal pain stimuli. Only the more demanding divided attention task has the capability to distract the focus of attention to the pain stimuli. Therefore, the pain patients are capable of performing within normal limits. Based on these findings chronic pain patients' attentional deficits should be appropriately evaluated and considered for insurance and work related matters. The effect of a successful distraction away from the pain in the divided attention task can also open new therapeutic aspects.


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