A systematic review and meta-analysis to compare the prevalence of depression between people with and without Type 1 and Type 2 diabetes

2021 ◽  
Author(s):  
Aaisha Farooqi ◽  
Clare Gillies ◽  
Harini Sathanapally ◽  
Sophia Abner ◽  
Sam Seidu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Meta Analysis ◽  
Prevalence Of Depression

scholarly journals Prevalence and Risk Factors of Depression in Chinese Patients With Type 2 Diabetes Mellitus: a Protocol of Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Xiaobo LIU ◽  
Chao Dong ◽  
Hong Jiang ◽  
Dongling Zhong ◽  
Yuxi Li ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Early Detection ◽  
Meta Analysis ◽  
Prevalence Of Depression ◽  
Associated Risk Factors

Abstract Background: The prevalence of type 2 diabetes mellitus (T2DM) is growing in China. Both physical and psychological complications occur along with the development of T2DM. The patients with depression account for a significant proportion of T2DM. Depressive symptoms interfere with blood glucose management, leading to poorer treatment outcome and even relate to the occurrence of other serious complications of T2DM population. Among these T2DM patients with depression, early detection and treatment is essential and effective. Knowledge of the current prevalence of depression in T2DM patients as well as associated risk factors may be meaningful for healthcare planning. Therefore, we plan to conduct a systematic review and meta-analysis to evaluate the Chinese prevalence of depression in T2DM and explore associated risk factors.Methods: We will search literatures recorded in MEDLINE/PubMed, EMBASE, the Cochrane Library, Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), and Wanfang database (Wanfang Data). The grey literatures and reference list will be manually searched. We will include population-based, cross-sectional surveys that investigated the Chinese prevalence of depression in T2DM or/and researched the possible risk factors. Two reviewers will screen studies, extract data and evaluate quality independently. We will assess inter-rater agreement between reviewers for study inclusion, data extraction, and study quality assessment using Kappa statistics. The primary outcome will be the pooled Chinese prevalence of depression in T2DM patients. The secondary outcome will contain the potential risk factors for depression in patients with T2DM. R software (version 3.6.1) and STATA software (version 12) will be used for data analysis.Discussion: This systematic review will provide comprehensive evidence of the Chinese prevalence and risk factors of depression in patients with T2DM. we expect to provide evidence basis for healthcare practitioners and policy makers to pay attention to the mental health of T2DM. Our data will highlight the need and importance of early detection and intervention for depression in patients with T2DM. Systematic review registration: PROSPERO CRD42020182979.

Prevalence and risk factors of fatigue in type 1 and type 2 diabetes: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Debby Syahru Romadlon ◽  
Faizul Hasan ◽  
Bayu Satria Wiratama ◽  
Hsiao‐Yean Chiu
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Meta Analysis

scholarly journals The risk of hip and non-vertebral fractures in type 1 and type 2 diabetes: A systematic review and meta-analysis update

Bone ◽  
2020 ◽  
Vol 137 ◽  
pp. 115457 ◽  
Author(s):  
Tatiane Vilaca ◽  
Marian Schini ◽  
Susan Harnan ◽  
Anthea Sutton ◽  
Edith Poku ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Vertebral Fractures ◽  
Meta Analysis

scholarly journals Incidence and prevalence of hypoglycaemia in type 1 and type 2 diabetes individuals: A systematic review and meta-analysis

2020 ◽  
Vol 170 ◽  
pp. 108522
Author(s):  
Hassan Alwafi ◽  
Alaa A. Alsharif ◽  
Li Wei ◽  
Dean Langan ◽  
Abdallah Y. Naser ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Meta Analysis

A Systematic Review and Meta-Analysis to Examine the Prevalence of Co-Morbid Depression in People with Type 1 and Type 2 Diabetes

2020 ◽  
Author(s):  
Aaisha Farooqi ◽  
Clare Gillies ◽  
Harini Sathanapally ◽  
Sophia C. Abner ◽  
Sam Seidu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Meta Analysis

scholarly journals Clinical efficacy and safety of insulin aspart compared with regular human insulin in patients with type 1 and type 2 diabetes: a systematic review and meta-analysis

2015 ◽  
Vol 125 (3) ◽  
pp. 141-151
Author(s):  
Piotr Wojciechowski ◽  
Patrycja Niemczyk-Szechowska ◽  
Elżbieta Olewińska ◽  
Patrycja Jaros ◽  
Barbara Mierzejewska ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Human Insulin ◽  
Clinical Efficacy ◽  
Insulin Aspart ◽  
Meta Analysis ◽  
Regular Human Insulin ◽  
Efficacy And Safety

scholarly journals The Efficacy of Mobile Phone Apps for Lifestyle Modification in Diabetes: Systematic Review and Meta-Analysis (Preprint)

2018 ◽  
Author(s):  
Xinghan Wu ◽  
Xitong Guo ◽  
Zhiwei Zhang
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Mobile Phone ◽  
Lifestyle Modification ◽  
Meta Analysis ◽  
Short Term

BACKGROUND Diabetes and related complications are estimated to cost US $727 billion worldwide annually. Type 1 diabetes, type 2 diabetes, and gestational diabetes are three subtypes of diabetes that share the same behavioral risk factors. Efforts in lifestyle modification, such as daily physical activity and healthy diets, can reduce the risk of prediabetes, improve the health levels of people with diabetes, and prevent complications. Lifestyle modification is commonly performed in a face-to-face interaction, which can prove costly. Mobile phone apps provide a more accessible platform for lifestyle modification in diabetes. OBJECTIVE This review aimed to summarize and synthesize the clinical evidence of the efficacy of mobile phone apps for lifestyle modification in different subtypes of diabetes. METHODS In June 2018, we conducted a literature search in 5 databases (Cochrane Central Register of Controlled Trials, MEDLINE, Embase, CINAHL, and PsycINFO). We evaluated the studies that passed screening using The Cochrane Collaboration’s risk of bias tool. We conducted a meta-analysis for each subtype on the mean difference (between intervention and control groups) at the posttreatment glycated hemoglobin (HbA1c) level. Where possible, we analyzed subgroups for short-term (3-6 months) and long-term (9-12 months) studies. Heterogeneity was assessed using the I2 statistic. RESULTS We identified total of 2669 articles through database searching. After the screening, we included 26 articles (23 studies) in the systematic review, of which 18 studies (5 type 1 diabetes, 11 type 2 diabetes, and 2 prediabetes studies) were eligible for meta-analysis. For type 1 diabetes, the overall effect on HbA1c was statistically insignificant (P=.46) with acceptable heterogeneity (I2=39%) in the short-term subgroup (4 studies) and significant heterogeneity between the short-term and long-term subgroups (I2=64%). Regarding type 2 diabetes, the overall effect on HbA1c was statistically significant (P<.01) in both subgroups, and when the 2 subgroups were combined, there was virtually no heterogeneity within and between the subgroups (I2 range 0%-2%). The effect remained statistically significant (P<.01) after adjusting for publication bias using the trim and fill method. For the prediabetes condition, the overall effect on HbA1c was statistically insignificant (P=.67) with a large heterogeneity (I2=65%) between the 2 studies. CONCLUSIONS There is strong evidence for the efficacy of mobile phone apps for lifestyle modification in type 2 diabetes. The evidence is inconclusive for the other diabetes subtypes.

scholarly journals MECHANISMS IN ENDOCRINOLOGY: Diabetes mellitus, a state of low bone turnover – a systematic review and meta-analysis

2017 ◽  
Vol 176 (3) ◽  
pp. R137-R157 ◽  
Author(s):  
Katrine Hygum ◽  
Jakob Starup-Linde ◽  
Torben Harsløf ◽  
Peter Vestergaard ◽  
Bente L Langdahl
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Bone Resorption ◽  
Bone Turnover ◽  
Meta Analysis ◽  
Patients With Diabetes ◽  
Low Bone Turnover

Objective To investigate the differences in bone turnover between diabetic patients and controls. Design A systematic review and meta-analysis. Methods A literature search was conducted using the databases Medline at PubMed and EMBASE. The free text search terms ‘diabetes mellitus’ and ‘bone turnover’, ‘sclerostin’, ‘RANKL’, ‘osteoprotegerin’, ‘tartrate-resistant acid’ and ‘TRAP’ were used. Studies were eligible if they investigated bone turnover markers in patients with diabetes compared with controls. Data were extracted by two reviewers. Results A total of 2881 papers were identified of which 66 studies were included. Serum levels of the bone resorption marker C-terminal cross-linked telopeptide (−0.10 ng/mL (−0.12, −0.08)) and the bone formation markers osteocalcin (−2.51 ng/mL (−3.01, −2.01)) and procollagen type 1 amino terminal propeptide (−10.80 ng/mL (−12.83, −8.77)) were all lower in patients with diabetes compared with controls. Furthermore, s-tartrate-resistant acid phosphatase was decreased in patients with type 2 diabetes (−0.31 U/L (−0.56, −0.05)) compared with controls. S-sclerostin was significantly higher in patients with type 2 diabetes (14.92 pmol/L (3.12, 26.72)) and patients with type 1 diabetes (3.24 pmol/L (1.52, 4.96)) compared with controls. Also, s-osteoprotegerin was increased among patients with diabetes compared with controls (2.67 pmol/L (0.21, 5.14)). Conclusions Markers of both bone formation and bone resorption are decreased in patients with diabetes. This suggests that diabetes mellitus is a state of low bone turnover, which in turn may lead to more fragile bone. Altered levels of sclerostin and osteoprotegerin may be responsible for this.

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