The place of 5-aminolaevulinic acid-photodynamic therapy in the treatment landscape of urethral warts: A systematic review

2021 ◽  
Vol 33 ◽  
pp. 102204
Author(s):  
Elio Kechichian ◽  
Elie Helou ◽  
Julien Sarkis ◽  
Claude Hayek ◽  
Chris Labaki ◽  
...  
2021 ◽  
Vol 34 ◽  
pp. 102221 ◽  
Author(s):  
Pollyanna C.V. Conrado ◽  
Karina M. Sakita ◽  
Glaucia S. Arita ◽  
Camila B. Galinari ◽  
Renato S. Gonçalves ◽  
...  

2021 ◽  
Vol 14 (3) ◽  
pp. 229
Author(s):  
Yo Shinoda ◽  
Daitetsu Kato ◽  
Ryosuke Ando ◽  
Hikaru Endo ◽  
Tsutomu Takahashi ◽  
...  

5-Aminolevulinic acid (5-ALA) is an amino acid derivative and a precursor of protoporphyrin IX (PpIX). The photophysical feature of PpIX is clinically used in photodynamic diagnosis (PDD) and photodynamic therapy (PDT). These clinical applications are potentially based on in vitro cell culture experiments. Thus, conducting a systematic review and meta-analysis of in vitro 5-ALA PDT experiments is meaningful and may provide opportunities to consider future perspectives in this field. We conducted a systematic literature search in PubMed to summarize the in vitro 5-ALA PDT experiments and calculated the effectiveness of 5-ALA PDT for several cancer cell types. In total, 412 articles were identified, and 77 were extracted based on our inclusion criteria. The calculated effectiveness of 5-ALA PDT was statistically analyzed, which revealed a tendency of cancer-classification-dependent sensitivity to 5-ALA PDT, and stomach cancer was significantly more sensitive to 5-ALA PDT compared with cancers of different origins. Based on our analysis, we suggest a standardized in vitro experimental protocol for 5-ALA PDT.


2017 ◽  
Vol 17 ◽  
pp. A60
Author(s):  
K.M. Tewari ◽  
E. Yaghini ◽  
O. Reelfs ◽  
R. Dondi ◽  
C. Pourzand ◽  
...  

2017 ◽  
Vol 18 ◽  
pp. 54-62 ◽  
Author(s):  
Fabian Cieplik ◽  
Wolfgang Buchalla ◽  
Elmar Hellwig ◽  
Ali Al-Ahmad ◽  
Karl-Anton Hiller ◽  
...  

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