Efficacy and safety of hemoporfin photodynamic therapy for port-wine stains in paediatric patients: A retrospective study of 439 cases at a single centre

2021 ◽  
Vol 36 ◽  
pp. 102568
Author(s):  
Tan Chun-hua ◽  
Gan Li-qiang ◽  
Wang Hua ◽  
Zhang Jian ◽  
Ni si-li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Retrospective Study ◽  
Efficacy And Safety ◽  
Port Wine ◽  
Single Centre ◽  
Port Wine Stains ◽  
Paediatric Patients

Retrospective study of photodynamic therapy for pulsed dye laser‐resistant port‐wine stains

2020 ◽  
Vol 47 (4) ◽  
pp. 348-355 ◽  
Author(s):  
Yue Han ◽  
Hanru Ying ◽  
Xiaolin Zhang ◽  
Wenxin Yu ◽  
Qingqing Cen ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Retrospective Study ◽  
Dye Laser ◽  
Pulsed Dye Laser ◽  
Port Wine ◽  
Port Wine Stains

Retrospective study of the treatment of port-wine stains with 595-nm pulsed dye laser in 261 Chinese patients

2020 ◽  
Vol 35 (8) ◽  
pp. 1811-1819
Author(s):  
Dong Li ◽  
Bin Chen ◽  
Hao Zhang ◽  
Yuan Yuan ◽  
Wenxin Fan ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Dye Laser ◽  
Pulsed Dye Laser ◽  
Chinese Patients ◽  
Port Wine ◽  
Port Wine Stains

scholarly journals Efficacy of hemoporfin photodynamic therapy for pulsed dye laser-resistant facial port-wine stains in 107 children: A retrospective study

2021 ◽  
Vol 0 ◽  
pp. 1-6
Author(s):  
Li-Chao Zhang ◽  
Jun Yang ◽  
Yuan-Bo Huang ◽  
Ming-Ye Bi
Keyword(s):  
Photodynamic Therapy ◽  
Response Rate ◽  
Dye Laser ◽  
Pulsed Dye Laser ◽  
Lateral Part ◽  
Port Wine ◽  
Cure Rate ◽  
Port Wine Stains ◽  
The Face ◽  
Better Than

Background: Port-wine stains occur in 0.3–0.5% newborns, mainly on the face and neck. Pulsed dye laser is recognized as the gold standard treatment; nevertheless, it is associated with a low cure rate and a high recurrence rate. Aims: This study aims to evaluate the efficacy of hemoporfin photodynamic therapy for pulsed dye laser-resistant port-wine stains in children. Methods: We studied 107 children who received hemoporfin photodynamic therapy for port-wine stains on the face and neck that were resistant to pulsed dye laser. After intravenous injection of 5 mg/kg hemoporfin, the local lesion was irradiated with 532 nm LED green light for 20 min with a power density of 80–100 mW/cm2. A total of 65 patients were given a second treatment after eight weeks. The efficacy and therapeutic responses were recorded at four days and eight weeks after each treatment. Results: The efficacy was positively correlated with the number of treatments received; two treatment sessions yielded significantly better results compared to a single treatment with a response rate of 96.9%, a significant response rate of 50.8% and a cure rate of 21.5%, respectively (P < 0.001). After two treatment sessions, the efficacy was negatively correlated with age (P = 0.04). The efficacy for port-wine stains located on the lateral part was better than that of the central face (P = 0.04). The efficacy for the pink type was better than that for the red and purple types (P = 0.03). No allergic or systematic adverse reactions were reported. Limitations: No objective measurement data were available. Conclusion: Hemoporfin photodynamic therapy is effective and safe for pulsed dye laser-resistant facial port-wine stains in children.

Efficacy and safety of lacosamide as an adjunctive therapy for refractory focal epilepsy in paediatric patients: a retrospective single-centre study

2015 ◽  
Vol 17 (4) ◽  
pp. 436-443 ◽  
Author(s):  
Jean-François Toupin ◽  
Anne Lortie ◽  
Philippe Major ◽  
Paola Diadori ◽  
Michel Vanasse ◽  
...  
Keyword(s):  
Adjunctive Therapy ◽  
Focal Epilepsy ◽  
Efficacy And Safety ◽  
Single Centre ◽  
Centre Study ◽  
Paediatric Patients ◽  
Single Centre Study
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