scholarly journals Epstein–Barr virus-associated infectious mononucleosis causing upper airway obstruction in a child with a history of adenoid hypertrophy

2020 ◽  
Vol 61 (1) ◽  
pp. 127-128
Author(s):  
Xin-Tian He ◽  
Chiao-Hua Lee ◽  
Po-Wei Wu ◽  
Chih-Chien Wang
Keyword(s):  
Airway Obstruction ◽  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Upper Airway ◽  
Upper Airway Obstruction ◽  
Adenoid Hypertrophy ◽  
Barr Virus ◽  
History Of ◽  
Epstein Barr

Airway Obstruction in Children with Infectious Mononucleosis

1995 ◽  
Vol 74 (9) ◽  
pp. 630-638 ◽  
Author(s):  
Daniel L. Wohl ◽  
Jon E. Isaacson
Keyword(s):  
Airway Obstruction ◽  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Upper Airway ◽  
Upper Airway Obstruction ◽  
Clinical Severity ◽  
Prolonged Intubation ◽  
Barr Virus ◽  
Inflammatory Edema ◽  
Epstein Barr

Epstein-Barr Virus (EBV) infection generally has a benign clinical course. Upper airway obstruction is a known complication requiring the otolaryngologist's attention. EBV is usually associated with adolescence but has been increasingly documented in younger children. We review 36 pediatric admissions for infectious mononucleosis over a 12-year period at our institution, 11 of which required consultation for airway obstruction. Airway management was based on clinical severity and ranged from monitored observation, with or without nasopharyngeal stenting, to prolonged intubation or emergent tonsilloadenoidectomy. A rare case of a four-year-old with near total upper airway obstruction secondary to panpharyngeal and transglottic inflammatory edema prompted this review and is reported. The otolaryngologist must recognize the potential severity of EBV-related airway compromise and be prepared to manage it.

Massive retropharyngeal lymphadenopathy in an infant: an unusual presentation of infectious mononucleosis

2004 ◽  
Vol 118 (12) ◽  
pp. 983-984 ◽  
Author(s):  
Sudhir Lobo ◽  
H. Williams ◽  
V. Singh
Keyword(s):  
Airway Obstruction ◽  
Infectious Mononucleosis ◽  
Upper Airway ◽  
Upper Airway Obstruction ◽  
Uneventful Recovery ◽  
Retropharyngeal Space ◽  
Upper Respiratory Tract ◽  
Barr Virus ◽  
Short Period ◽  
Epstein Barr

Infectious mononucleosis causing upper airway obstruction due to tonsillar disease and associated lymphadenopathy in adolescents is well recognized. However, infection with Epstein-Barr virus (EBV) in a young child of six months is rare. The authors present such a case, with massive swelling of the retropharyngeal lymph nodes, that has not been published previously. The patient presented to this department with a short history of an upper respiratory tract infection and mild upper airway obstruction. On examination there was a massive enlargement of the retropharyngeal space with a compromised airway. This was confirmed on X-ray. She made an uneventful recovery following incision and drainage and a short period of endotracheal intubation. Because of the presence of retropharyngeal lymphoid tissue in infancy an alternative site of upper airway obstruction may occur here in this age group.

scholarly journals Evidence of genetic susceptibility to infectious mononucleosis: a twin study

2011 ◽  
Vol 140 (11) ◽  
pp. 2089-2095 ◽  
Author(s):  
A. E. HWANG ◽  
A. S. HAMILTON ◽  
M. G. COCKBURN ◽  
R. AMBINDER ◽  
J. ZADNICK ◽  
...  
Keyword(s):  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Genetic Factors ◽  
Population Based ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
History Of ◽  
Epstein Barr ◽  
Barr Virus Infection

SUMMARYInfectious mononucleosis is a clinical manifestation of primary Epstein–Barr virus infection. It is unknown whether genetic factors contribute to risk. To assess heritability, we compared disease concordance in monozygotic to dizygotic twin pairs from the population-based California Twin Program and assessed the risk to initially unaffected co-twins. One member of 611 and both members of 58 twin pairs reported a history of infectious mononucleosis. Pairwise concordance in monozygotic and dizygotic pairs was respectively 12·1% [standard error (s.e.)=1·9%] and 6·1% (s.e.=1·2%). The relative risk (hazard ratio) of monozygotic compared to dizygotic unaffected co-twins of cases was 1·9 [95% confidence interval (CI) 1·1–3·4, P=0·03], over the follow-up period. When the analysis was restricted to same-sex twin pairs, that estimate was 2·5 (95% CI 1·2–5·3, P=0·02). The results are compatible with a heritable contribution to the risk of infectious mononucleosis.

Glandular fever and Epstein-Barr virus-related polyneuropathy: a life-threatening complication

2020 ◽  
Vol 13 (10) ◽  
pp. e235678
Author(s):  
Colm Brendan Dorris ◽  
Donna Gallagher ◽  
Myles Black
Keyword(s):  
Epstein Barr Virus ◽  
Upper Airway ◽  
Surgical Tracheostomy ◽  
Barr Virus ◽  
Glandular Fever ◽  
Life Threatening ◽  
History Of ◽  
Life Threatening Complication ◽  
Epstein Barr ◽  
Multiple Cranial Nerve

An 18-year-old woman presented with a 1-week history of sore throat, lethargy and fevers. She was subsequently diagnosed with glandular fever and was managed conservatively. Following 1 week of conservative measures, she developed acute upper airway obstruction requiring emergency surgical tracheostomy insertion. Further investigation including electromyography demonstrated multiple cranial nerve neuropathies.

Airway Obstruction in a Young Adult With Infectious Mononucleosis by Epstein-Barr Virus

2008 ◽  
Vol 16 (1) ◽  
pp. 79
Author(s):  
Nikolaos Papadopoulos ◽  
Anastasios Liverezas ◽  
Nikolaos Antonakopoulos ◽  
Apostolos Karathanasis ◽  
Georgios Apostolopoulos
Keyword(s):  
Young Adult ◽  
Airway Obstruction ◽  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr

Diagnosis of infectious mononucleosis caused by Epstein-Barr virus in infants

2010 ◽  
Vol 52 (4) ◽  
pp. 536-540 ◽  
Author(s):  
Sumitaka Dohno ◽  
Akihiko Maeda ◽  
Yoshihito Ishiura ◽  
Tetsuya Sato ◽  
Mikiya Fujieda ◽  
...  
Keyword(s):  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Acute Acalculous Cholecystitis Due to a Primary Epstein Barr Virus Infection in a Pediatric Patient

2021 ◽  
Vol 13 (1) ◽  
pp. 86-90
Author(s):  
Carlos Leganés Villanueva ◽  
Ilaria Goruppi ◽  
Nuria Brun Lozano ◽  
Federica Bianchi ◽  
María Quinteiro González ◽  
...  
Keyword(s):  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Acalculous Cholecystitis ◽  
Acute Acalculous Cholecystitis ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
Acute Complications ◽  
Epstein Barr ◽  
Barr Virus Infection ◽  
Human Viruses

Epstein–Barr virus (EBV) is estimated to infect more than 98% of adults worldwide and is one of the most common human viruses. Acute acalculous cholecystitis (AAC) of the gallbladder is an atypical complication of infectious mononucleosis caused by EBV. Conservative management has been described in the context of AAC caused by EBV. A surgical approach must be considered in the case of acute complications such as perforation or gallbladder gangrene. We present the case of a 10-year-old female patient with AAC due to infectious mononucleosis syndrome caused by primary EBV infection.

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