Aims:
To develop an efficient protocol, which involves an elegant exploration of the catalytic
potential of both the room temperature and surfactant ionic liquids towards the synthesis of
biologically important derivatives of 2-aminothiazole.
Objective:
Specific heat capacity data as a function of temperature for the synthesized 2-
aminothiazole derivatives has been advanced by exploring their thermal profiles.
Method:
The thermal gravimetry analysis and differential scanning calorimetry techniques are
used systematically.
Results:
The present strategy could prove to be a useful general strategy for researchers working
in the field of surfactants and surfactant based ionic liquids towards their exploration in organic
synthesis. In addition to that, effect of electronic parameters on the melting temperature of the
corresponding 2-aminothiazole has been demonstrated with the help of thermal analysis. Specific
heat capacity data as a function of temperature for the synthesized 2-aminothiazole derivatives
has also been reported.
Conclusion:
Melting behavior of the synthesized 2-aminothiazole derivatives is to be described
on the basis of electronic effects with the help of thermal analysis. Additionally, the specific heat
capacity data can be helpful to the chemists, those are engaged in chemical modelling as well as
docking studies. Furthermore, the data also helps to determine valuable thermodynamic
parameters such as entropy and enthalpy.
