Voluntary exercise enhances activity rhythms and ameliorates anxiety- and depression-like behaviors in the sand rat model of circadian rhythm-related mood changes

2015 ◽  
Vol 151 ◽  
pp. 441-447 ◽  
Author(s):  
Katy Tal-Krivisky ◽  
Noga Kronfeld-Schor ◽  
Haim Einat
Keyword(s):  
Circadian Rhythm ◽  
Rat Model ◽  
Voluntary Exercise ◽  
Anxiety And Depression ◽  
Sand Rat ◽  
Activity Rhythms ◽  
Mood Changes

Voluntary exercise blocks ongoing pain and diminishes bone remodeling while sparing protective mechanical pain in a rat model of advanced osteoarthritis pain

Pain ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kaylee Townsend ◽  
Ian Imbert ◽  
Victoria Eaton ◽  
Glenn W. Stevenson ◽  
Tamara King
Keyword(s):  
Bone Remodeling ◽  
Rat Model ◽  
Voluntary Exercise ◽  
Osteoarthritis Pain ◽  
Ongoing Pain

scholarly journals Modest Amounts of Voluntary Exercise Reduce Pain- and Stress-Related Outcomes in a Rat Model of Persistent Hind Limb Inflammation

2017 ◽  
Vol 18 (6) ◽  
pp. 687-701 ◽  
Author(s):  
Mark H. Pitcher ◽  
Farid Tarum ◽  
Imran Z. Rauf ◽  
Lucie A. Low ◽  
Catherine Bushnell
Keyword(s):  
Rat Model ◽  
Hind Limb ◽  
Voluntary Exercise

CircRNA-WNK2 acts as a ceRNA for miR-328a-3p to promote AANAT expression in the male rat pineal gland

Endocrinology ◽  
2021 ◽  
Author(s):  
Yi Zheng ◽  
Hao-Qi Wang ◽  
Hai-Xiang Guo ◽  
Heng-Li Xie ◽  
Wei-Di Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Circadian Rhythm ◽  
Pineal Gland ◽  
Rat Model ◽  
Noncoding Rnas ◽  
Luciferase Reporter ◽  
Male Rat ◽  
Biological Functions ◽  
Melatonin Secretion ◽  
Rat Pineal Gland

Abstract Noncoding RNAs (ncRNAs), including miRNAs and circRNAs, which are expressed with a daily rhythm in the rat pineal gland, are associated with the regulation of melatonin secretion and other biological functions. However, the mechanisms of these molecules in the rat pineal gland are not yet fully understood. In this study, we found circR-WNK2 was highly expressed at night, which may be involved in the regulation of melatonin secretion through the ceRNA mechanism. By dual luciferase reporter, RNA pulldown, and FISH assays, we found that miR-328a-3p can target circR-WNK2 and the Aa-nat mRNA 3’UTR. Transfection experiments indicated that circR-WNK2 could competitively bind to miR-328a-3p, reduce miR-328a-3p expression, and promote Aa-nat gene expression and melatonin secretion. And by constructing an SCGx rat model, we found that ncRNAs expressed in the pineal gland was regulated by signals from the SCN. This finding supports the hypothesis that these noncoding RNAs may interact to shape the circadian rhythm through transcriptional processing in melatonin synthesis.

scholarly journals Hypothalamic Neuronal Loss and Altered Circadian Rhythm of Temperature in a Rat Model of Mesial Temporal Lobe Epilepsy

Epilepsia ◽  
1999 ◽  
Vol 40 (12) ◽  
pp. 1688-1696 ◽  
Author(s):  
Mark Quigg ◽  
Hope Clayburn ◽  
Martin Straume ◽  
Michael Menaker ◽  
Edward H. Bertram
Keyword(s):  
Circadian Rhythm ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Rat Model ◽  
Neuronal Loss ◽  
Mesial Temporal Lobe Epilepsy ◽  
Mesial Temporal Lobe

Circadian Rhythm of Intraocular Pressure: A Rat Model

1995 ◽  
Vol 27 (3) ◽  
pp. 163-167 ◽  
Author(s):  
Rohit Krishna ◽  
André Mermoud ◽  
George Baerveldt ◽  
Don S. Minckler
Keyword(s):  
Circadian Rhythm ◽  
Intraocular Pressure ◽  
Rat Model
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