Impacts of stereoregularity and stereocomplex formation on physicochemical, protein adsorption and cell adhesion behaviors of star-shaped 8-arms poly(ethylene glycol)–poly(lactide) block copolymer films

Polymer ◽  
2007 ◽  
Vol 48 (9) ◽  
pp. 2649-2658 ◽  
Author(s):  
Koji Nagahama ◽  
Yoshihiro Nishimura ◽  
Yuichi Ohya ◽  
Tatsuro Ouchi
Keyword(s):  
Cell Adhesion ◽  
Block Copolymer ◽  
Ethylene Glycol ◽  
Protein Adsorption ◽  
Poly Ethylene Glycol ◽  
Copolymer Films ◽  
Stereocomplex Formation ◽  
Poly Ethylene

scholarly journals Methoxy-Poly(ethylene glycol) Modified Poly(L-lactide) Enhanced Cell Affinity of Human Bone Marrow Stromal Cells by the Upregulation of 1-Cadherin and Delta-2-catenin

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Xueli Mao ◽  
Zetao Chen ◽  
Junqi Ling ◽  
Jingjing Quan ◽  
Hui Peng ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Adhesion ◽  
Ethylene Glycol ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Poly Ethylene Glycol ◽  
Copolymer Films ◽  
Cell Affinity ◽  
Poly Ethylene

Poly(l-lactide) (PLLA), a versatile biodegradable polymer, is one of the most commonly-used materials for tissue engineering applications. To improve cell affinity for PLLA, poly(ethylene glycol) (PEG) was used to develop diblock copolymers. Human bone marrow stromal cells (hBMSCs) were cultured on MPEG-b-PLLA copolymer films to determine the effects of modification on the attachment and proliferation of hBMSC. The mRNA expression of 84 human extracellular matrix (ECM) and adhesion molecules was analyzed using RT-qPCR to understand the underlying mechanisms. It was found that MPEG-b-PLLA copolymer films significantly improved cell adhesion, extension, and proliferation. This was found to be related to the significant upregulation of two adhesion genes, CDH1 and CTNND2, which encode 1-cadherin and delta-2-catenin, respectively, two key components for the cadherin-catenin complex. In summary, MPEG-b-PLLA copolymer surfaces improved initial cell adhesion by stimulation of adhesion molecule gene expression.

Phase Transition Behavior, Protein Adsorption, and Cell Adhesion Resistance of Poly(ethylene glycol) Cross-Linked Microgel Particles

2005 ◽  
Vol 6 (4) ◽  
pp. 2032-2039 ◽  
Author(s):  
Christine M. Nolan ◽  
Catherine D. Reyes ◽  
Justin D. Debord ◽  
Andrés J. García ◽  
L. Andrew Lyon
Keyword(s):  
Phase Transition ◽  
Cell Adhesion ◽  
Ethylene Glycol ◽  
Protein Adsorption ◽  
Poly Ethylene Glycol ◽  
Phase Transition Behavior ◽  
Transition Behavior ◽  
Microgel Particles ◽  
Poly Ethylene

Strong resistance of poly (ethylene glycol) based L -tyrosine polyurethanes to protein adsorption and cell adhesion

2011 ◽  
Vol 61 (4) ◽  
pp. 616-621 ◽  
Author(s):  
Jui-Chen Yang ◽  
Chao Zhao ◽  
I-Fan Hsieh ◽  
Senthilram Subramanian ◽  
Lingyun Liu ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Ethylene Glycol ◽  
Protein Adsorption ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

scholarly journals Protein adsorption and cell adhesion on nanoscale bioactive coatings formed from poly(ethylene glycol) and albumin microgels

Biomaterials ◽  
2008 ◽  
Vol 29 (34) ◽  
pp. 4481-4493 ◽  
Author(s):  
Evan A. Scott ◽  
Michael D. Nichols ◽  
Lee H. Cordova ◽  
Brandon J. George ◽  
Young-Shin Jun ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Ethylene Glycol ◽  
Protein Adsorption ◽  
Poly Ethylene Glycol ◽  
Bioactive Coatings ◽  
Poly Ethylene

scholarly journals Functionalized Poly(ethylene glycol)-Based Bioassay Surface Chemistry That Facilitates Bio-Immobilization and Inhibits Nonspecific Protein, Bacterial, and Mammalian Cell Adhesion

2007 ◽  
Vol 19 (18) ◽  
pp. 4405-4414 ◽  
Author(s):  
Gregory M. Harbers ◽  
Kazunori Emoto ◽  
Charles Greef ◽  
Steven W. Metzger ◽  
Heather N. Woodward ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Ethylene Glycol ◽  
Surface Chemistry ◽  
Mammalian Cell ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Measurements of Interbilayer Forces and Protein Adsorption on Uncharged Lipid Bilayers Displaying Poly(ethylene glycol) Chains†

Biochemistry ◽  
2000 ◽  
Vol 39 (12) ◽  
pp. 3441-3451 ◽  
Author(s):  
Nadezhda V. Efremova ◽  
Bruce Bondurant ◽  
David F. O'Brie ◽  
Deborah E. Leckband
Keyword(s):  
Ethylene Glycol ◽  
Protein Adsorption ◽  
Lipid Bilayers ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Poly(ethylene glycol) Grafting to Poly(ether imide) Membranes: Influence on Protein Adsorption and Thrombocyte Adhesion

2013 ◽  
Vol 13 (12) ◽  
pp. 1720-1729 ◽  
Author(s):  
Axel T. Neffe ◽  
Maik von Ruesten-Lange ◽  
Steffen Braune ◽  
Karola Luetzow ◽  
Toralf Roch ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Protein Adsorption ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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