Synthesis, characterization, and controllable drug release of dendritic star-block copolymer by ring-opening polymerization and atom transfer radical polymerization

A completely metal-free strategy was developed by combining Atom Transfer Radical Polymerization (ATRP) and Ring Opening Polymerization (ROP) for the syntheses of block copolymers.

Download Full-text

Novel Chemoenzymatic Synthesis of Triblock Copolymer

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.396-398.2459 ◽

2011 ◽

Vol 396-398 ◽

pp. 2459-2462

Author(s):

Xiao Tian Liu ◽

Hong Bo Fan

Keyword(s):

Block Copolymer ◽

Atom Transfer Radical Polymerization ◽

Radical Polymerization ◽

Ring Opening ◽

Triblock Copolymer ◽

Sebacic Acid ◽

Ring Opening Polymerization ◽

Chemoenzymatic Synthesis ◽

Atom Transfer ◽

Novozyme 435

Enzymatic polycondensation of benzyl-2,2-bis(methylol) propionate and sebacic acid has been performed using lipase Novozyme-435 as the catalyst, subsequently enzymatic ring-opening polymerization was reacted by adding ε-caprolactone as the monomer in the same system. Then atom transfer radical polymerization (ATRP) from the macroinitiator combining α-bromoester of styrene was catalyzed by CuCl/2,2’-Dipyridyl to obtain the block copolymer successfully. The polymers obtained in different conditions were analyzed by 1HNMR and GPC.

Download Full-text

Synthesis of PCL-PS Star-Block Copolymer by Combination of Lipase-Catalyzed Ring-Opening Polymerization and ATRP

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.11-12.749 ◽

2006 ◽

Vol 11-12 ◽

pp. 749-752 ◽

Cited By ~ 2

Author(s):

Rui Xue Liu ◽

Yan Shi ◽

Zhi Feng Fu

Keyword(s):

Block Copolymer ◽

Block Copolymers ◽

Atom Transfer Radical Polymerization ◽

Radical Polymerization ◽

1H Nmr ◽

Ring Opening ◽

Ring Opening Polymerization ◽

Star Block Copolymer ◽

Star Block Copolymers

Poly(ε-caprolactone) (PCL)-polystyrene (PS)star-block copolymer with a cross-linked microgel core were synthesized by the combination of atom transfer radical polymerization (ATRP) of St and lipase-catalyzed ring-opening polymerization (ROP) of ε-CL. The characterization of PCL-Br, PCL-PS-Br macroinitiator and PCL-PS Star-block copolymers was detected by GPC and 1H NMR. Results showed that the target star-block copolymers were successfully prepared.

Download Full-text

One-step synthesis of poly(methacrylate)-b-polyester via “one organocatalyst, two polymerizations”

Polymer Chemistry ◽

10.1039/d1py00892g ◽

2021 ◽

Author(s):

Mengmeng Li ◽

Lin Zhou ◽

Ziqi Zhang ◽

Qi Wang ◽

Jiani Gao ◽

...

Keyword(s):

Block Copolymer ◽

Methyl Methacrylate ◽

Ambient Temperature ◽

Atom Transfer Radical Polymerization ◽

Radical Polymerization ◽

Ring Opening ◽

Ring Opening Polymerization ◽

Atom Transfer ◽

Trimethylene Carbonate ◽

One Step

By using triarylsulfonium hexafluorophosphate salt as an organocatalyst for both photo-controlled atom transfer radical polymerization (photo-ATRP) and ring-opening polymerization (ROP) at ambient temperature, well-deﬁned poly(methyl methacrylate)-b-poly(trimethylene carbonate) block copolymer was...

Download Full-text

Synthesis of binary-patterned brushes by combining atom transfer radical polymerization and ring-opening polymerization

e-Polymers ◽

10.1515/epoly-2013-0109 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 2

Author(s):

Aurore Olivier ◽

Franck Meyer ◽

Jean-Marie Raquez ◽

Philippe Dubois

Keyword(s):

Atom Transfer Radical Polymerization ◽

Radical Polymerization ◽

Ring Opening ◽

Microcontact Printing ◽

Gold Surface ◽

Ring Opening Polymerization ◽

Careful Study ◽

Atom Transfer ◽

Final Thickness ◽

End Group

Abstract This paper report the synthesis of binary-patterned brushes, combining two distinctive surface initiated-polymerizations (SIP) on the basis of different propagating species: the SI Ring Opening Polymerization (ROP) of L-Lactide (LLA) and SI atom transfer radical polymerization (ATRP) of N,N’-dimethylaminoethyl methacrylate (DMAEMA) on gold surface. First of all, a careful study of surfaceinitiated ROP of L-Lactide from hydroxyl end-group of thiol monolayer on gold surface as catalyzed by metal-free catalyst was carried out. The PLLA brushes synthesis was evaluated using two types of thiol monolayer and revealed the influence of ROP initiator chain length on the final thickness of the PLLA film. Combining the soft lithographic technique, microcontact printing, and the liquid phase deposition, the deposition onto specific micro-domains of both initiators was performed. The growth of PDMAEMA brushes and PLLA brushes was conducted by successive ATRP and ROP.

Download Full-text