The in vitro and in vivo degradation behavior of poly (trimethylene carbonate-co-ε-caprolactone) implants

Polymer ◽  
2014 ◽  
Vol 55 (20) ◽  
pp. 5111-5124 ◽  
Author(s):  
Liqun Yang ◽  
Jianxin Li ◽  
Shu Meng ◽  
Ying Jin ◽  
Jinzhe Zhang ◽  
...  
Biomaterials ◽  
2006 ◽  
Vol 27 (9) ◽  
pp. 1741-1748 ◽  
Author(s):  
Zheng Zhang ◽  
Roel Kuijer ◽  
Sjoerd K. Bulstra ◽  
Dirk W. Grijpma ◽  
Jan Feijen

2009 ◽  
Vol 1190 ◽  
Author(s):  
Bernhard Hiebl ◽  
Karl Kratz ◽  
Rosemarie Fuhrmann ◽  
Friedrich Jung ◽  
Andres Lendlein ◽  
...  

AbstractThe degradation behavior of biodegradable multiblock copolymers (PDC) containing poly(p-dioxanone) hard segments (PPDO) and crystallizable poly(epsilon-caprolactone) switching segments (PCL) synthesized via co-condensation of two oligomeric macrodiols with an aliphatic diisocyanate as junction unit was explored in in vivo and in vitro experiments. The in vitro experiments for enzymatic degradation resulted that the poly(epsilon-caprolactone) segments are degraded faster, than the poly(p-dioxanone) segments. During degradation the outer layer of the test specimen becomes porous. Finally non-soluble degradation products in form of particles were found at the surface. This observation is in good agreement with the in vivo studies, where the non-soluble degradation products in the periimplantary tissues showed a diameter of 1 – 3 micron.


2020 ◽  
Vol 5 (2) ◽  
pp. 275-285 ◽  
Author(s):  
Kai Chen ◽  
Xinhui Xie ◽  
Hongyan Tang ◽  
Hui Sun ◽  
Ling Qin ◽  
...  

2008 ◽  
Vol 19 (4) ◽  
pp. 453-466 ◽  
Author(s):  
Sung Mook Lim ◽  
Dae Kun Song ◽  
Se Heang Oh ◽  
Dong Sin Lee-Yoon ◽  
Eun Hee Bae ◽  
...  

2016 ◽  
Vol 42 (11) ◽  
pp. 1732-1741 ◽  
Author(s):  
Zhen Li ◽  
Jinxu Cao ◽  
Beibei Hu ◽  
Heran Li ◽  
Hongzhuo Liu ◽  
...  

2020 ◽  
Vol 574 ◽  
pp. 118870 ◽  
Author(s):  
Moran Haim Zada ◽  
Awanish Kumar ◽  
Omar Elmalak ◽  
Elana Markovitz ◽  
Ruthy Icekson ◽  
...  

2004 ◽  
Vol 5 (4) ◽  
pp. 1303-1309 ◽  
Author(s):  
Sung In Jeong ◽  
Byung-Soo Kim ◽  
Young Moo Lee ◽  
Kyo Jin Ihn ◽  
Soo Hyun Kim ◽  
...  

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