Oleaginous yeast Yarrowia lipolytica mutants with a disrupted fatty acyl-CoA synthetase gene accumulate saturated fatty acid

2011 ◽  
Vol 46 (7) ◽  
pp. 1436-1441 ◽  
Author(s):  
Jinjing Wang ◽  
Borun Zhang ◽  
Shulin Chen
Keyword(s):  
Fatty Acid ◽  
Yarrowia Lipolytica ◽  
Saturated Fatty Acid ◽  
Oleaginous Yeast ◽  
Fatty Acyl ◽  
Yeast Yarrowia Lipolytica

scholarly journals Stable isotope and chemical inhibition analyses suggested the existence of a non-mevalonate-like pathway in the yeast Yarrowia lipolytica

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sivamoke Dissook ◽  
Tomohisa Kuzuyama ◽  
Yuri Nishimoto ◽  
Shigeru Kitani ◽  
Sastia Putri ◽  
...  
Keyword(s):  
Yarrowia Lipolytica ◽  
Oleaginous Yeast ◽  
Isoprenoid Biosynthesis ◽  
Mep Pathway ◽  
Authentic Standard ◽  
Chemical Inhibition ◽  
Chromatographic Peaks ◽  
Methyl Erythritol Phosphate ◽  
Limiting Condition ◽  
Yeast Yarrowia Lipolytica

AbstractMethyl erythritol phosphate (MEP) is the metabolite found in the MEP pathway for isoprenoid biosynthesis, which is known to be utilized by plants, algae, and bacteria. In this study, an unprecedented observation was found in the oleaginous yeast Yarrowia lipolytica, in which one of the chromatographic peaks was annotated as MEP when cultivated in the nitrogen limiting condition. This finding raised an interesting hypothesis of whether Y. lipolytica utilizes the MEP pathway for isoprenoid biosynthesis or not, because there is no report of yeast harboring the MEP pathway. Three independent approaches were used to investigate the existence of the MEP pathway in Y. lipolytica; the spiking of the authentic standard, the MEP pathway inhibitor, and the 13C labeling incorporation analysis. The study suggested that the mevalonate and MEP pathways co-exist in Y. lipolytica and the nitrogen limiting condition triggers the utilization of the MEP pathway in Y. lipolytica.

Metabolic engineering for ricinoleic acid production in the oleaginous yeast Yarrowia lipolytica

2013 ◽  
Vol 98 (1) ◽  
pp. 251-262 ◽  
Author(s):  
A. Beopoulos ◽  
J. Verbeke ◽  
F. Bordes ◽  
M. Guicherd ◽  
M. Bressy ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Ricinoleic Acid ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Oleaginous Yeast ◽  
Yeast Yarrowia Lipolytica

Heterologous production of pentane in the oleaginous yeast Yarrowia lipolytica

2013 ◽  
Vol 165 (3-4) ◽  
pp. 184-194 ◽  
Author(s):  
John Blazeck ◽  
Leqian Liu ◽  
Rebecca Knight ◽  
Hal S. Alper
Keyword(s):  
Yarrowia Lipolytica ◽  
Oleaginous Yeast ◽  
Heterologous Production ◽  
Yeast Yarrowia Lipolytica

Glutamate dehydrogenases in the oleaginous yeast Yarrowia lipolytica

Yeast ◽  
2019 ◽  
Vol 37 (1) ◽  
pp. 103-115
Author(s):  
Pamela J. Trotter ◽  
Karen Juco ◽  
Ha T. Le ◽  
Kjersten Nelson ◽  
Lizeth I. Tamayo ◽  
...  
Keyword(s):  
Yarrowia Lipolytica ◽  
Oleaginous Yeast ◽  
Yeast Yarrowia Lipolytica
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