In order to ensure the safe, stable operation of Guangzhou power grid to meet the large city power grid requirements, reached the international advanced level, to realize the transformation of Guangzhou electric power dispatching control center strategy and control mode, it requires the construction of a new generation of intelligent dispatching technical support system. This paper analyzes the current situation and development of Guangzhou power grid. Based on the rapid development of smart grid technology and information technology, this paper puts forward the development direction of power grid dispatching technology support system. It also puts forward the construction work of reasonable planning, makes clear about construction content and technical support system to meet the overall business needs “integration of regulation and control, the integration of main distribution network, market-oriented support”. And we make theoretical exploration and practice and accumulated experience for the new generation of power dispatching intelligent technical support system development.