scholarly journals Comparative Analysis of 5-Year Clinical Outcomes and Patterns of Failure of Proton Beam Therapy Versus Intensity Modulated Radiation therapy for Prostate Cancer in the Postoperative Setting

Author(s):  
Andrew R. Barsky ◽  
Ruben Carmona ◽  
Vivek Verma ◽  
Patricia M.G. Santos ◽  
Stefan Both ◽  
...  
Rare Tumors ◽  
2019 ◽  
Vol 11 ◽  
pp. 203636131987851 ◽  
Author(s):  
Nathan Y Yu ◽  
Sujay A Vora

Retroperitoneal chordomas are exceedingly rare and account for less than 5% of all primary bone malignancies. Their etiology remains unknown. We report a rare case of an extravertebral chordoma of the retroperitoneum in a 71-year-old man treated with surgical resection and post-operative spot-scanning proton beam therapy. We describe how to safely treat a retroperitoneal target to a prescription dose over 70 Gy (relative biological effectiveness) with spot-scanning proton beam therapy and also report a dosimetric comparison of spot-scanning proton beam therapy versus intensity-modulated radiation therapy. This case not only highlights a rare diagnosis of an extravertebral retroperitoneal chordoma but it also draws attention to the dosimetric advantages of proton beam therapy and illustrates a promising radiotherapeutic option for retroperitoneal targets.


Cancer ◽  
2019 ◽  
Vol 125 (23) ◽  
pp. 4278-4293 ◽  
Author(s):  
Patricia Mae G. Santos ◽  
Andrew R. Barsky ◽  
Wei‐Ting Hwang ◽  
Curtiland Deville ◽  
Xingmei Wang ◽  
...  

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