A Pooled Toxicity Analysis of Moderately Hypofractionated Proton Beam Therapy and Intensity Modulated Radiation Therapy in Early-Stage Prostate Cancer Patients

Author(s):  
Neha Vapiwala ◽  
J. Karen Wong ◽  
Elizabeth Handorf ◽  
Jonathan Paly ◽  
Amardeep Grewal ◽  
...  
2020 ◽  
Vol 57 (1) ◽  
pp. 70
Author(s):  
HalilCumhur Yildirim ◽  
SefikaArzu Ergen ◽  
Emine Sedef ◽  
Merve Sahin ◽  
SongulCavdar Karacam ◽  
...  

Rare Tumors ◽  
2019 ◽  
Vol 11 ◽  
pp. 203636131987851 ◽  
Author(s):  
Nathan Y Yu ◽  
Sujay A Vora

Retroperitoneal chordomas are exceedingly rare and account for less than 5% of all primary bone malignancies. Their etiology remains unknown. We report a rare case of an extravertebral chordoma of the retroperitoneum in a 71-year-old man treated with surgical resection and post-operative spot-scanning proton beam therapy. We describe how to safely treat a retroperitoneal target to a prescription dose over 70 Gy (relative biological effectiveness) with spot-scanning proton beam therapy and also report a dosimetric comparison of spot-scanning proton beam therapy versus intensity-modulated radiation therapy. This case not only highlights a rare diagnosis of an extravertebral retroperitoneal chordoma but it also draws attention to the dosimetric advantages of proton beam therapy and illustrates a promising radiotherapeutic option for retroperitoneal targets.


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