Extrapulmonary tuberculosis: mimicking metastases in a patient with melanoma in a high TB-burden country; case report

Background. Tuberculous pachymeningitis is a rare form of extrapulmonary tuberculosis usually suspected from the detection of thickening of the dura in contrast-enhanced magnetic resonance imaging. Progressive nature of the disease can lead to chronic headache with focal neurological signs due to compression from the thickened dura. Case Report. We report a 40-year-old female who presented with chronic headache over a decade associated with recurrent neurological abnormalities including optic neuritis, hemisensory loss, migraine, facial nerve palsy, and recurrent vertigo. Although there was an initial perceived response to steroids, the patient had a subsequent progressive course. On investigations, she was found to have a diffused dural thickening on contrast MRI with a strongly positive Mantoux test with caseating necrotizing granulomatous inflammation on dural histology. With initiation of antituberculous medication with steroids, the patient markedly improved, and the medication for tuberculosis was continued for a year with good response. Conclusion. Primary tuberculous pachymeningitis should be suspected in a patient complaining of prolonged headache with focal neurological signs when MRI evidence of dural thickening is detected, and another focus of tuberculosis was not found. Prompt suspicion with image-guided dural biopsy for histology would help to confirm the diagnosis.

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Peritoneal Tuberculosis Presenting as Chronic Ascites With Scrofula: A Case Report

Clinical Management Issues ◽

10.7175/cmi.v13i1.1416 ◽

2019 ◽

Vol 13 (1) ◽

Author(s):

Galina Bogoslovskaya ◽

Jose Zaldivar

Keyword(s):

Case Report ◽

Early Diagnosis ◽

Extrapulmonary Tuberculosis ◽

Young Female ◽

Ca 125 ◽

Test Results ◽

Peritoneal Tuberculosis ◽

Clinical Presentations ◽

High Index Of Suspicion ◽

Diagnostic Delays

Peritoneal tuberculosis (PTB) is a common type of extrapulmonary tuberculosis; however, due to variety of clinical presentations, diagnostic challenges do occur. The nonspecific features of this disease can lead to diagnostic delays and the development of complications. In addition, PTB can mimic a malignancy, especially in women who present with ascites and elevated cancer antigen (CA) 125 levels. A high index of suspicion is an important factor in an early diagnosis. Moreover, an early diagnosis and the initiation of antituberculous therapy are essential for preventing morbidity and mortality. Fortunately, most of these patients respond very well to standard antituberculous therapy.Here, we have reported the case of a young female patient who presented with chronic ascites, mild abdominal tenderness, and later, scrofula. Ultimately, she was diagnosed with PTB based on her test results. We expect that this case report will contribute to the existing literature on this subject.

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Case report: Tuberculous mastoiditis an uncommon presentation of extrapulmonary tuberculosis in a young immunocompetant adult male

Journal of Respiratory Diseases and Medicine ◽

10.15761/jrdm.1000108 ◽

2020 ◽

Vol 2 (1) ◽

Author(s):

Pradeep Kumar ◽

Vidyadhara Lakkappan ◽

Suhas Thorat ◽

Alan Andrade

Keyword(s):

Case Report ◽

Adult Male ◽

Extrapulmonary Tuberculosis ◽

Uncommon Presentation ◽

Tuberculous Mastoiditis

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Diagnostic Challenge Of Peritoneal Tuberculosis In Woman With Ascites

Biomolecular and Health Science Journal ◽

10.20473/bhsj.v3i1.19131 ◽

2020 ◽

Vol 3 (1) ◽

pp. 49

Author(s):

Nenci Siagian ◽

Muhammad Vitanata Arfijanto

Keyword(s):

Case Report ◽

Extrapulmonary Tuberculosis ◽

Peritoneal Tuberculosis ◽

Diagnostic Challenge ◽

Major Health ◽

Pulmonary Tb ◽

Radiologic Examination ◽

Global Issue ◽

The World ◽

The One

Tuberculosis (TB) is a major health global issue including extrapulmonary tuberculosis (EPTB). The one of manifestation of EPTB is peritoneal TB that constitutes 2% from all cases of pulmonary TB around the world. The diagnosis of peritoneal TB is quite challenging because many cases have symptom that similar to other diseases and those often necessary need further specific examinations such as PCR, culture and radiologic examination. We reported a case report of peritoneal tuberculosis in woman with ascites.

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COMPLICATED LUMBAR TUBERCULOUS SPONDYLODISCITIS IN DISSEMINATED TUBERCULOSIS, TREATED USING A NON-CONVENTIONAL ANTERIOR SUPPORT SYSTEM FOR HYDROSTATIC DISTRACTION: A CASE REPORT

Acta Ortopédica Brasileira ◽

10.1590/1413-785220182606178095 ◽

2018 ◽

Vol 26 (6) ◽

pp. 401-405

Author(s):

Alex Oliveira de Araujo ◽

Thiago Queiroz Soares ◽

Alessandro Gonzalez Torelli ◽

Allan Hiroshi de Araujo Ono ◽

Raphael Martus Marcon ◽

...

Keyword(s):

Case Report ◽

Support System ◽

Extrapulmonary Tuberculosis ◽

Psoas Muscle ◽

Spinal Instability ◽

Lumbar Region ◽

Level Of Evidence ◽

Disseminated Tuberculosis ◽

Anterior Support ◽

Tuberculous Spondylodiscitis

ABSTRACT Objective: To describe a case of disseminated tuberculosis affecting the lumbar spine that was treated using a non-conventional anterior support system. Background: Tuberculous spondylodiscitis is the most common and most severe form of extrapulmonary tuberculosis. Although antibiotic therapy is the most frequently used treatment, surgery is necessary in cases of neurological deficit, spinal instability, significant deformity, severe sepsis, paravertebral and epidural abscesses or in cases wherein clinical treatment has failed. A surgical procedure is also indicated when a biopsy is required. With the development of new methods for reconstruction and fixation of the spine, complete debridement of the tuberculous foci has become an increasingly common approach, but there is a lack consensus on the best technique. Methods and results: The patient suffered from disseminated tuberculosis affecting the lumbar region of the spine, with an abscess in the psoas muscle. He underwent extensive debridement via both anterior and posterior approaches, using a non-conventional anterior support system that promotes hydrostatic distraction. Conclusions: Treatment using the hydrostatic distraction system was able to reestablish both the stability and anatomy of the lumbar curve. Level of evidence IV, Case report.

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Extrapulmonary tuberculosis – A case report

10.1055/s-0038-1639940 ◽

2018 ◽

Author(s):

MR Reissig ◽

S Balster ◽

T Stöver

Keyword(s):

Case Report ◽

Extrapulmonary Tuberculosis

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Addison's disease as a primary manifestation of extrapulmonary tuberculosis; A case report

Indian Journal of Tuberculosis ◽

10.1016/j.ijtb.2020.08.005 ◽

2020 ◽

Author(s):

Nithin Ranawaka ◽

N.H. Welikumbura

Keyword(s):

Case Report ◽

Extrapulmonary Tuberculosis ◽

Addison’S Disease ◽

Addison's Disease

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Multidrug resistant tuberculous meningitis in pregnancy: a rare case report

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20191245 ◽

2019 ◽

Vol 8 (4) ◽

pp. 1692

Author(s):

U. Nagashree ◽

Charumathi . ◽

U. Meenakshisundaram

Keyword(s):

Case Report ◽

Rare Case ◽

Extrapulmonary Tuberculosis ◽

Multidrug Resistant ◽

Pulmonary Tb ◽

Foetal Growth ◽

Rare Case Report ◽

Surgical Options ◽

Extra Pulmonary ◽

Tuberculosis Meningitis

The prevalence of tuberculosis, especially extrapulmonary tuberculosis is increasing worldwide. TB meningitis is one of severe manifestations of extra pulmonary TB. Prognosis of cases of multidrug resistance tuberculosis meningitis is worse and even more challenging in pregnant women. It’s mostly associated with increased frequency of maternal disability, hospitalisation during pregnancy, foetal growth retardation, prematurity, low-birth weight and increased perinatal mortality. As information on outcome of pregnancy among women with extra pulmonary TB is limited; various medical and surgical options for timely management has been discussed. Authors bring out a case report of a primigravida at 26 weeks gestation with severe multidrug resistant TB meningitis who was successfully managed at our hospital with a healthy infant.

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