Prospective evaluation of acute toxicity and patient reported outcomes in anal cancer and plan optimization

2018 ◽  
Vol 128 (2) ◽  
pp. 375-379 ◽  
Author(s):  
Camilla Kronborg ◽  
Eva Serup-Hansen ◽  
Anna Lefevre ◽  
Eva E. Wilken ◽  
Jørgen B. Petersen ◽  
...  
2018 ◽  
Vol 120 ◽  
pp. e889-e901 ◽  
Author(s):  
Ori Barzilai ◽  
Lily McLaughlin ◽  
Mary-Kate Amato ◽  
Anne S. Reiner ◽  
Shahiba Q. Ogilvie ◽  
...  

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 695-695
Author(s):  
Melissa Frick ◽  
Carolyn Vachani ◽  
Margaret K. Hampshire ◽  
Christina Bach ◽  
Karen Arnold-Korzeniowski ◽  
...  

695 Background: There is significant need for quality follow-up care to optimize long-term outcomes for the growing population of lower gastrointestinal (GI) cancer survivors. Patient-reported outcomes (PROs) provide valuable information regarding late- and long-term effects. Methods: Using a convenience sample from 1,129 colon, rectal and anal cancer survivors (n=792, 218, and 119, respectively) who utilized an Internet-based survivorship care plan (SCP) tool, we examined patient-reported demographics, treatment, and toxicity data. Responses from a follow-up survey were reviewed. Results: Median age of diagnosis was 51 years and median current age was 54 years. 81% of respondents were Caucasian and 58% were female. The most commonly reported late- and long-term effects for all survivors were neuropathy (65%), fatigue (56%), cognitive changes (49%), changes in GI function (43%), sexual dysfunction (22% in males, 43% in females), and radiation-induced dermatologic effects including changes in color/texture of skin (39%) and loss of flexibility in radiated areas (31%). The prevalence of these effects varied with length of time since treatment and treatment modality. Anal cancer patients reported a high prevalence of sexual dysfunction and radiation-induced dermatologic effects. Over 87% of users reported satisfaction levels of "good" to "excellent" using this tool, and 69% reported they intend to share SCP with their healthcare team. Conclusions: For lower GI cancer survivors, it is feasible to obtain PROs from an Internet-based survivorship tool. Survivors report a wide spectrum of late- and long-term side effects, which can be used to inform counseling at time of diagnosis, as well as help anticipate and respond to disease- and treatment-related sequelae during follow-up. We are among the first to report on PROs in anal cancer survivors. Further investigation on the impact of SCPs on healthcare communication and use is needed.


2017 ◽  
Vol 28 ◽  
pp. iii59-iii60
Author(s):  
Camilla Kronborg ◽  
Eva Serup-Hansen ◽  
Annette Schouboe ◽  
Cecilie Lefevre Anna ◽  
Eva Wilken ◽  
...  

2007 ◽  
Vol 29 (5) ◽  
pp. 909-917 ◽  
Author(s):  
Maria Domenica Cappellini ◽  
Mohamed Bejaoui ◽  
Leyla Agaoglu ◽  
John Porter ◽  
Thomas Coates ◽  
...  

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