Adapted physical activity intervention among adults with cancer undergoing hematopoietic stem cell transplantation (HSCT): A feasibility study

Introduction Caregivers of patients undergoing hematopoietic stem cell transplantation need encouragement to maintain their own wellbeing. This feasibility study explored a six-session wellness intervention for caregivers entitled Ready to CARE (Connect, Actively Relax, and Exercise). Method This study used a single-arm pre–post design to explore the feasibility and acceptability of the intervention and study procedures. The individual, participant-directed intervention was initiated at hospitalization for stem cell reinfusion. Caregivers completed telephone surveys on four occasions and engaged in one semi-structured interview to share their perceptions of the intervention. Results Twenty participants enrolled and completed the baseline survey, with 50%, 90%, and 80% completing the subsequent three surveys, respectively. Seventy-four percent completed all six sessions of the intervention. Caregivers most often used the sessions to set goals related to physical activity (36%), stress management (14%), sleep (13%), and caregiving tasks (11%). Caregivers reported appreciation of the intervention’s focus on supporting caregivers, taking action with goal-setting, and allowing caregivers to determine the focus of the goals. Scheduling the sessions was the most problematic aspect of the intervention. Conclusion While caregivers were open to a wellness intervention, a high degree of flexibility and tailoring is needed to engage and support busy caregivers. Clinical Trial Registration: NCT03210727

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A pilot feasibility study of non-myeloablative allogeneic hematopoietic stem cell transplantation for refractory Crohn Disease

Bone Marrow Transplantation ◽

10.1038/s41409-020-0953-y ◽

2020 ◽

Vol 55 (12) ◽

pp. 2343-2346 ◽

Cited By ~ 1

Author(s):

Richard K. Burt ◽

Robert Craig ◽

Laura Yun ◽

Amy Halverson ◽

Kathleen Quigley ◽

...

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Feasibility Study ◽

Crohn Disease ◽

Hematopoietic Stem ◽

Pilot Feasibility Study

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Individualized in-hospital exercise training program for people undergoing hematopoietic stem cell transplantation: a feasibility study

Disability and Rehabilitation ◽

10.1080/09638288.2019.1626493 ◽

2019 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Aline P. Fioritto ◽

Cristino C. Oliveira ◽

Vanessa S. Albuquerque ◽

Leonardo B. Almeida ◽

Catherine L. Granger ◽

...

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Exercise Training ◽

Stem Cell Transplantation ◽

Training Program ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Feasibility Study ◽

Hematopoietic Stem ◽

Exercise Training Program

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Daily performance status-based target physical activity of early rehabilitation for hematologic malignancy patients after allogeneic hematopoietic stem cell transplantation.

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.15_suppl.e17020 ◽

2012 ◽

Vol 30 (15_suppl) ◽

pp. e17020-e17020

Author(s):

Junichiro Inoue ◽

Rei Ono ◽

Atsuo Okamura ◽

Naomi Kiyota ◽

Daisuke Makiura ◽

...

Keyword(s):

Physical Activity ◽

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Hematologic Malignancy ◽

Performance Status ◽

Eastern Cooperative Oncology Group ◽

Hematopoietic Stem

e17020 Background: For hematologic malignancy patients receiving allogeneic hematopoietic stem cell transplantation (allo-SCT), the maintenance and/or increase of physical activity (PA) after allo-SCT possibly lead to favorable outcomes. However, it remains to be clarified how much intensity of daily rehabilitation should be prescribed. The aim of this study was to evaluate target PA according to daily performance status (PS) in these patients. Methods: Twenty-seven allo-SCT patients were enrolled in this study (13 males, 14 females, the median age; 47 years). Written informed consent was obtained from all patients. Donor types were bone marrow (n = 12), peripheral blood stem cell (n = 6), and single-unit cord blood (n = 9). All patients received our established exercise program supervised by physical therapists just after neutrophil engraftment in a bioclean room. As an alternative value of PA, daily steps (DS) were measured by using a uniaxial pedometer (Lifecorder EX, Suzuken Co. Ltd., Nagoya, Japan), and Eastern Cooperative Oncology Group PS after allo-SCT were also assessed daily for each individual. The data were statistically analyzed by using ANOVA and Scheff 's tests. Results: A correlation between DS and PS was observed. After the early physical intervention, the mean DS of patients with PS 1, 2, or 3 in a bioclean room were 2,411 ± 1,068, 1,205 ± 572, and 597 ± 216 steps/day, respectively. DS significantly declined by about 50% according to one grade deterioration of PS. Conclusions: As the target PA correlated with PS seems to be existence, we should plan daily activity in a bioclean room to keep more than above-mentioned mean DS according to daily PS for allo-SCT patients.

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High-dose Chemotherapy and Hematopoietic Stem Cell Transplantation for Patients with Nasopharyngeal Cancer: a Feasibility Study

Japanese Journal of Clinical Oncology ◽

10.1093/jjco/hyg064 ◽

2003 ◽

Vol 33 (7) ◽

pp. 331-335 ◽

Cited By ~ 2

Author(s):

T.-Y. Chen

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Feasibility Study ◽

Nasopharyngeal Cancer ◽

High Dose Chemotherapy ◽

High Dose ◽

Hematopoietic Stem

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The Usability of the Preliminary ICF Core Set for Hospitalized Patients After a Hematopoietic Stem Cell Transplantation From the Perspective of Nurses: A Feasibility Study

Frontiers in Rehabilitation Sciences ◽

10.3389/fresc.2021.710127 ◽

2021 ◽

Vol 2 ◽

Author(s):

Hillegonda A. Stallinga ◽

Janita Bakker ◽

Sylvia J. Haan ◽

Harmieke van Os-Medendorp ◽

Marijke C. Kars ◽

...

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Feasibility Study ◽

Successful Implementation ◽

Hematopoietic Stem ◽

Icf Core Set ◽

Core Set

Background: A hematopoietic stem cell transplantation (HSCT) has a major impact on the functioning and perceived quality of life of patients. To describe the functioning of patients, a preliminary set of 53 categories of the International Classification of Functioning, Disability and Health (ICF) as relevant for HSCT patients has been selected earlier by a Delphi study. For the implementation of this preliminary ICF core set for patients after HSCT in clinical practice, a feasibility study was requested.Methods: A feasibility study was conducted in an explanatory mixed-methods research design. Qualitative data were collected cross-sectionally by semi-structured interviews based on specific topics related to feasibility regarding the use of the preliminary ICF core set for HSCT patients from the perspective of nurses (five in ICF-trained nurses and five regular, untrained, nurses). Quantitative data, were collected longitudinally by using a mobile health application based on ICF in which the ICF trained nurses registered HSCT patients' functioning.Results: Qualitative analysis indicated that using the preliminary ICF core set is practical and acceptable for providing information about the functioning of HSCT patients from the perspective of nurses. In addition, nurses indicated a demand for this information due to its impact on multidisciplinary meetings and clinical decision-making by involving relevant aspects of the functioning of patients. Management support, trained staff, and designated time to focus on functioning are mentioned as requirements for successful implementation. Quantitative analysis demonstrated that the most used 30% (n = 17) ICF categories are included in the preliminary ICF core set for HSCT patients (n = 24). Energy (b130) was the most used ICF category. Family relationships (d760) was the most frequently and highly positively associated ICF category.Conclusions: From the perspective of nurses, the preliminary ICF core set for HSCT patients is feasible and relevant in gaining information regarding functioning. Applying this preliminary ICF core set for HSCT patients in the anamnesis and the nursing consultations contributes to this information. Further research is needed to look at the perspective of other professionals and HSCT patients themselves.

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