Recombinant human thyrotropin stimulation prior to 131I therapy in toxic multinodular goiter with low radioactive iodine uptake

Author(s):  
M.J. Azorín Belda ◽  
A. Martínez Caballero ◽  
G.C. Figueroa Ardila ◽  
M. Martínez Ramírez ◽  
C.A. Gómez Jaramillo ◽  
...  
2011 ◽  
Vol 50 (16) ◽  
pp. 1709-1714 ◽  
Author(s):  
Toshio Kahara ◽  
Akiko Shimizu ◽  
Akio Uchiyama ◽  
Shintaro Terahata ◽  
Junichi Tajiri ◽  
...  

2018 ◽  
Vol 10 (3) ◽  
pp. 223-229
Author(s):  
M. R. Islam ◽  
F. N. Islam ◽  
M. M. Haque ◽  
M. S. Hossain ◽  
M. S. Reza ◽  
...  

The role of radioactive iodine uptake and scintigraphy were studied over 111 subjects with a mean age of 42±13 years, 65% females and 35% males, in the evaluation of hyperthyroidism with multinodular goiter. The uptake study was performed by oral administration of 4.5 – 10.0 μCi of 131I as sodium-iodide thyroid scintigraphy was performed 20 minutes after an intravenous injection of 2.0 – 4.0 mCi of 99mTc as pertechnetate. The Mean ± SD uptake values for the study subjects were found to be 36.1±15.4% ranging from 14% to 75% at 2 h and 59.9±15.9% ranging from 32% to 90% at 24 h measurements. The present results of uptake values clearly exceed the normal range (3% – 12% for 2 h; 8% – 25% for 24 h), which indicate the hyper-functioning of thyroid, and therefore, demonstrated successfully the efficient role of radioactive iodine uptake and scintigraphy to diagnose the hyperthyroidism. 


1960 ◽  
Vol XXXIII (IV) ◽  
pp. 584-592 ◽  
Author(s):  
B.-A. Lamberg ◽  
C. A. Hernberg ◽  
Riitta Hakkila

ABSTRACT Treatment with a thyroid preparation was used in 75 cases of non-toxic goitre. In 63 cases there was nodular goitre in 12 diffuse goitre. The observation period varied from 3 to 42 months. The size of the goitre decreased in 50 cases (68 per cent) of which 40 had a nodular goitre and 10 a diffuse goitre. In the 63 cases with a nodular goitre the size of the nodules decreased in 39 cases and the nodules disappeared completely in 2 cases (65 per cent). In 5 cases (7 per cent) there was no change in the size of the thyroid or the nodules. Temporary factitious hyperthyroidism appeared in 7 cases but subsided rapidly after adjustment of the dose. In one case an endogenous hyperthyroidism evidently developed, probably owing to initial latent hyperthyroidism. Treatment of non-toxic goitre with thyroid preparations or hormones is recommended 1) in diffuse goitre, 2) in nodular goitre as a trial and 3) after thyroidectomy for compressive goitre. The value of radioactive iodine uptake or excretion tests for the assessment of the response to treatment and the adjustment of the dose is emphasized.


1982 ◽  
Vol 7 (8) ◽  
pp. 368-369 ◽  
Author(s):  
J ACOSTA ◽  
R CHITKARA ◽  
F KHAN ◽  
V AZUETA ◽  
L SILVER

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