Radioiodine Therapy After Pretreatment With Recombinant Thyroid-Stimulating Hormone (TSH) in Toxic Multinodular Goiter With Low Radioactive Iodine Uptake

2010 ◽  
Vol 20 (5) ◽  
pp. 208-210
Author(s):  
Hema Padmanabhan
Keyword(s):  
Multinodular Goiter ◽  
Radioactive Iodine ◽  
Radioiodine Therapy ◽  
Thyroid Stimulating Hormone ◽  
Iodine Uptake ◽  
Toxic Multinodular Goiter ◽  
Radioactive Iodine Uptake ◽  
Stimulating Hormone

scholarly journals Toxic Multinodular Goiter with Low Radioactive Iodine Uptake

2011 ◽  
Vol 50 (16) ◽  
pp. 1709-1714 ◽  
Author(s):  
Toshio Kahara ◽  
Akiko Shimizu ◽  
Akio Uchiyama ◽  
Shintaro Terahata ◽  
Junichi Tajiri ◽  
...  
Keyword(s):  
Multinodular Goiter ◽  
Radioactive Iodine ◽  
Iodine Uptake ◽  
Toxic Multinodular Goiter ◽  
Radioactive Iodine Uptake

Endogenous Thyroid-Stimulating Hormone and Radioactive Iodine Uptake in Normal Subjects

2012 ◽  
Vol 37 (6) ◽  
pp. 584-586 ◽  
Author(s):  
Patricio González ◽  
Rodrigo Jaimovich ◽  
Verónica Araya ◽  
Teresa Massardo ◽  
Alberto Carmona
Keyword(s):  
Radioactive Iodine ◽  
Normal Subjects ◽  
Thyroid Stimulating Hormone ◽  
Iodine Uptake ◽  
Radioactive Iodine Uptake ◽  
Stimulating Hormone

Determination of remnant thyroid volume: comparison of ultrasonography, radioactive iodine uptake and serum thyroid-stimulating hormone level

2007 ◽  
Vol 122 (6) ◽  
pp. 615-622 ◽  
Author(s):  
Y Erbil ◽  
U Barbaros ◽  
A Salmaslıoglu ◽  
H Issever ◽  
M Tukenmez ◽  
...  
Keyword(s):  
Radioactive Iodine ◽  
Hormone Level ◽  
Thyroid Tissue ◽  
Thyroid Volume ◽  
Thyroid Stimulating Hormone ◽  
Iodine Uptake ◽  
Multinodular Goitre ◽  
Remnant Thyroid ◽  
Radioactive Iodine Uptake ◽  
Stimulating Hormone

AbstractPurpose:We aimed to evaluate the accuracy of ultrasonography, radioactive iodine uptake and serum thyroid-stimulating hormone level in predicting the volume of remnant thyroid gland.Methods:Sixty-six thyroidectomy patients were divided into two groups according to their functional status, i.e. those operated upon for nontoxic multinodular goitre (group one) and those operated upon for hyperthyroidism (group two). Ultrasonography, radioactive iodine uptake and thyroid-stimulating hormone assay were performed in all patients during the first post-operative month. The two groups were subdivided according to the amount of remnant thyroid volume detected on ultrasonography: <2 ml, 2–5 ml and >5 ml.Results:The remnant thyroid volume was positively correlated with the radioactive iodine uptake (rs = 0.684, p = 0.0001). The increase in remnant thyroid tissue radioactive iodine uptake was significantly greater in the patients operated upon for hyperthyroidism compared with those operated upon for nontoxic multinodular goitre (p = 0.0001). There was a negative correlation between remnant thyroid volume and post-operative serum thyroid-stimulating hormone level (rs =  −0.865, p = 0.0001) and between remnant thyroid tissue radioactive iodine uptake and post-operative serum thyroid-stimulating hormone level (rs = −0.682, p = 0.0001).Conclusion:Ultrasonography is a more accurate measure of remnant thyroid volume than radioactive iodine uptake in patients operated upon for hyperthyroidism, compared with those operated upon for nontoxic multinodular goitre.

scholarly journals Radioactive iodine uptake in hyperthyroid cats after administration of recombinant human thyroid stimulating hormone

2018 ◽  
Vol 32 (6) ◽  
pp. 1891-1896 ◽  
Author(s):  
Amy E. Oberstadt ◽  
Nathan C. Nelson ◽  
Andrew K. Claude ◽  
Kent R. Refsal ◽  
J. Catharine Scott-Moncrieff ◽  
...  
Keyword(s):  
Radioactive Iodine ◽  
Thyroid Stimulating Hormone ◽  
Iodine Uptake ◽  
Human Thyroid ◽  
Radioactive Iodine Uptake ◽  
Stimulating Hormone

scholarly journals Radioiodine Thyroid Uptake and Scintigraphy in the Evaluation of Hyperthyroidism with Multinodular Goiter

2018 ◽  
Vol 10 (3) ◽  
pp. 223-229
Author(s):  
M. R. Islam ◽  
F. N. Islam ◽  
M. M. Haque ◽  
M. S. Hossain ◽  
M. S. Reza ◽  
...  
Keyword(s):  
Multinodular Goiter ◽  
Sodium Iodide ◽  
Radioactive Iodine ◽  
Iodine Uptake ◽  
Thyroid Scintigraphy ◽  
Normal Range ◽  
Thyroid Uptake ◽  
The Mean ◽  
Radioactive Iodine Uptake

The role of radioactive iodine uptake and scintigraphy were studied over 111 subjects with a mean age of 42±13 years, 65% females and 35% males, in the evaluation of hyperthyroidism with multinodular goiter. The uptake study was performed by oral administration of 4.5 – 10.0 μCi of 131I as sodium-iodide thyroid scintigraphy was performed 20 minutes after an intravenous injection of 2.0 – 4.0 mCi of 99mTc as pertechnetate. The Mean ± SD uptake values for the study subjects were found to be 36.1±15.4% ranging from 14% to 75% at 2 h and 59.9±15.9% ranging from 32% to 90% at 24 h measurements. The present results of uptake values clearly exceed the normal range (3% – 12% for 2 h; 8% – 25% for 24 h), which indicate the hyper-functioning of thyroid, and therefore, demonstrated successfully the efficient role of radioactive iodine uptake and scintigraphy to diagnose the hyperthyroidism. 

TREATMENT OF NON-TOXIC GOITRE WITH THYROID PREPARATIONS

1960 ◽  
Vol XXXIII (IV) ◽  
pp. 584-592 ◽  
Author(s):  
B.-A. Lamberg ◽  
C. A. Hernberg ◽  
Riitta Hakkila
Keyword(s):  
Radioactive Iodine ◽  
Response To Treatment ◽  
Iodine Uptake ◽  
Nodular Goitre ◽  
Radioactive Iodine Uptake ◽  
Observation Period

ABSTRACT Treatment with a thyroid preparation was used in 75 cases of non-toxic goitre. In 63 cases there was nodular goitre in 12 diffuse goitre. The observation period varied from 3 to 42 months. The size of the goitre decreased in 50 cases (68 per cent) of which 40 had a nodular goitre and 10 a diffuse goitre. In the 63 cases with a nodular goitre the size of the nodules decreased in 39 cases and the nodules disappeared completely in 2 cases (65 per cent). In 5 cases (7 per cent) there was no change in the size of the thyroid or the nodules. Temporary factitious hyperthyroidism appeared in 7 cases but subsided rapidly after adjustment of the dose. In one case an endogenous hyperthyroidism evidently developed, probably owing to initial latent hyperthyroidism. Treatment of non-toxic goitre with thyroid preparations or hormones is recommended 1) in diffuse goitre, 2) in nodular goitre as a trial and 3) after thyroidectomy for compressive goitre. The value of radioactive iodine uptake or excretion tests for the assessment of the response to treatment and the adjustment of the dose is emphasized.

THYROID FUNCTION TESTS: A REVIEW

2021 ◽  
pp. 73-76
Author(s):  
Vasudev Sankhla ◽  
Aman Deep
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Radioactive Iodine ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Function Tests ◽  
Function Tests ◽  
Tsh Secretion ◽  
Line Test ◽  
Radioactive Iodine Uptake

Thyroid function tests are one of the most common endocrine panels in general practice because a good understanding of when to order them, indications for treatment are important for the optimal treatment of thyroid dysfunction. Thyroid-stimulating hormone (TSH) should be the rst test to be performed on any patient with suspected thyroid dysfunction and in follow-up of individuals on treatment. It is useful as a rst-line test because even small changes in thyroid function are sufcient to cause a signicant increase in TSH secretion. Thyroxine levels may be assessed in a patient with hyperthyroidism, to determine the severity of hyperthyroxinemia. Antithyroid peroxidase measurements should be considered while evaluating patients with subclinical hypothyroidism and can facilitate the identication of autoimmune thyroiditis during the evaluation of nodular thyroid disease. The measurement of TSH receptor antibody must be considered when conrmation of Graves’ disease is needed and radioactive iodine uptake cannot be done.

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