scholarly journals Radioiodine Thyroid Uptake and Scintigraphy in the Evaluation of Hyperthyroidism with Multinodular Goiter

2018 ◽  
Vol 10 (3) ◽  
pp. 223-229
Author(s):  
M. R. Islam ◽  
F. N. Islam ◽  
M. M. Haque ◽  
M. S. Hossain ◽  
M. S. Reza ◽  
...  
Keyword(s):  
Multinodular Goiter ◽  
Sodium Iodide ◽  
Radioactive Iodine ◽  
Iodine Uptake ◽  
Thyroid Scintigraphy ◽  
Normal Range ◽  
Thyroid Uptake ◽  
The Mean ◽  
Radioactive Iodine Uptake

The role of radioactive iodine uptake and scintigraphy were studied over 111 subjects with a mean age of 42±13 years, 65% females and 35% males, in the evaluation of hyperthyroidism with multinodular goiter. The uptake study was performed by oral administration of 4.5 – 10.0 μCi of 131I as sodium-iodide thyroid scintigraphy was performed 20 minutes after an intravenous injection of 2.0 – 4.0 mCi of 99mTc as pertechnetate. The Mean ± SD uptake values for the study subjects were found to be 36.1±15.4% ranging from 14% to 75% at 2 h and 59.9±15.9% ranging from 32% to 90% at 24 h measurements. The present results of uptake values clearly exceed the normal range (3% – 12% for 2 h; 8% – 25% for 24 h), which indicate the hyper-functioning of thyroid, and therefore, demonstrated successfully the efficient role of radioactive iodine uptake and scintigraphy to diagnose the hyperthyroidism. 

scholarly journals Toxic Multinodular Goiter with Low Radioactive Iodine Uptake

2011 ◽  
Vol 50 (16) ◽  
pp. 1709-1714 ◽  
Author(s):  
Toshio Kahara ◽  
Akiko Shimizu ◽  
Akio Uchiyama ◽  
Shintaro Terahata ◽  
Junichi Tajiri ◽  
...  
Keyword(s):  
Multinodular Goiter ◽  
Radioactive Iodine ◽  
Iodine Uptake ◽  
Toxic Multinodular Goiter ◽  
Radioactive Iodine Uptake

scholarly journals Thyroid scintigraphy in diagnosis of nodular and diffuse thyroid pathology

2020 ◽  
Vol 15 (4) ◽  
pp. 138-147
Author(s):  
Pavel O. Rumyantsev ◽  
Mikhail V. Degtyarev ◽  
Dali S. Dzeytova ◽  
Alexey A. Trukhin ◽  
Konstantin Y. Slashchuk ◽  
...  
Keyword(s):  
Laboratory Tests ◽  
Radioactive Iodine ◽  
Thyroid Tissue ◽  
Thyroid Scintigraphy ◽  
Thyroid Pathology ◽  
99Mtc Pertechnetate ◽  
Thyroid Uptake ◽  
History Of ◽  
Medical Interest

Diagnosis of the causes of thyrotoxicosis (destruction or increased functional activity of the thyroid tissue in nodular and diffuse thyroid pathology) is a key point in determining the management of patients with this pathology. Scintigraphy is the method of choice in differential diagnosis of the causes of thyrotoxicosis assessing the functional state of the thyroid gland. According to variable medical interest, thyroid scintigraphy can be performed using 99mTc-pertechnetate or radioactive iodine isotopes (123I, 124I, 131I). For thyroid uptake evaluation used scintigraphy with 99mTc-pertechnetate radiopharmaceutical, which is not organificates and quickly excretes from thyroid tissue. In case of thyroid iodine pharmacokinetics investigation radiopharmaceuticals labeled by iodine isotopes (123I,131I, 124I) are used. The review includes original scintigrams, tables and diagrams. Article shows thyroid scintigraphy informativity analysis, evaluates the place and role of the thyroid scintigraphy examinations in modern diagnostic algorithms taking into account the history of the disease, laboratory tests, ultrasound (TIRADS) and result ofFNA (Bethesda). Additionally authors focused on existing clinical guidelines analysis. An optimized algorithm for the diagnosis and treatment of diffuse and/or nodular thyroid pathology associated with thyrotoxicosis is proposed.

TREATMENT OF NON-TOXIC GOITRE WITH THYROID PREPARATIONS

1960 ◽  
Vol XXXIII (IV) ◽  
pp. 584-592 ◽  
Author(s):  
B.-A. Lamberg ◽  
C. A. Hernberg ◽  
Riitta Hakkila
Keyword(s):  
Radioactive Iodine ◽  
Response To Treatment ◽  
Iodine Uptake ◽  
Nodular Goitre ◽  
Radioactive Iodine Uptake ◽  
Observation Period

ABSTRACT Treatment with a thyroid preparation was used in 75 cases of non-toxic goitre. In 63 cases there was nodular goitre in 12 diffuse goitre. The observation period varied from 3 to 42 months. The size of the goitre decreased in 50 cases (68 per cent) of which 40 had a nodular goitre and 10 a diffuse goitre. In the 63 cases with a nodular goitre the size of the nodules decreased in 39 cases and the nodules disappeared completely in 2 cases (65 per cent). In 5 cases (7 per cent) there was no change in the size of the thyroid or the nodules. Temporary factitious hyperthyroidism appeared in 7 cases but subsided rapidly after adjustment of the dose. In one case an endogenous hyperthyroidism evidently developed, probably owing to initial latent hyperthyroidism. Treatment of non-toxic goitre with thyroid preparations or hormones is recommended 1) in diffuse goitre, 2) in nodular goitre as a trial and 3) after thyroidectomy for compressive goitre. The value of radioactive iodine uptake or excretion tests for the assessment of the response to treatment and the adjustment of the dose is emphasized.

Radioactive Iodine Uptake by a Large Cell Undifferentiated Bronchogenic Carcinoma

1982 ◽  
Vol 7 (8) ◽  
pp. 368-369 ◽  
Author(s):  
J ACOSTA ◽  
R CHITKARA ◽  
F KHAN ◽  
V AZUETA ◽  
L SILVER
Keyword(s):  
Bronchogenic Carcinoma ◽  
Radioactive Iodine ◽  
Large Cell ◽  
Iodine Uptake ◽  
Radioactive Iodine Uptake
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