Implementation of mild therapeutic hypothermia therapy as standard care after successful CPR in a German general hospital

Resuscitation ◽  
2008 ◽  
Vol 77 ◽  
pp. S30
Author(s):  
M.J. Foedisch ◽  
A. Viehoefer ◽  
C.H. Knuth
2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Cristina Granja ◽  
Pedro Ferreira ◽  
Orquídea Ribeiro ◽  
João Pina

Aim. To evaluate whether the introduction of a therapeutic hypothermia (TH) protocol consisting of cold saline infusion and surface cooling would be effective in targeting mild therapeutic hypothermia (32–34∘C). Additionally, to evaluate if TH would improve survival after cardiac arrest.Design. Before-after design.Setting. General Intensive Care Unit (ICU) at an urban general hospital with 470 beds.Patients and Methods. Patients admitted in the ICU after cardiac arrest between 2004 and 2009 were included. Effectiveness of the TH protocol to achieve the targeted temperature was evaluated. Hospital mortality was compared before (October 2004–March 2006) and after (April 2006–September 2009) the protocol implementation.Results. Hundred and thirty patients were included, 75 patients were not submitted to TH (before TH group), and 55 were submitted to TH (TH group). There were no significant differences concerning baseline, ICU, and cardiac arrest characteristics between both groups. There was a significant reduction in hospital mortality from 61% () in the before TH group to 40% () in the TH group.Conclusion. Our protocol consisting of cold saline infusion and surface cooling might be effective in inducing and maintaining mild therapeutic hypothermia. TH achieved with this protocol was associated with a significant reduction in hospital mortality.


Author(s):  
Ala Nozari

This chapter provides a summary of the landmark study known as the HACA Trial. Does mild therapeutic hypothermia improve neurologic outcomes compared with standard care normothermia in patients surviving ventricular fibrillation or pulseless ventricular tachycardic arrest? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. Among the results, the preponderance of data suggests that temperature is an important variable for neurologic recovery after cardiac arrest. Guidelines suggest maintaining a target temperature between 32ºC and 36ºC for at least 24 hours after achieving target temperature. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.


Circulation ◽  
2012 ◽  
Vol 125 (1) ◽  
pp. 123-129 ◽  
Author(s):  
Sen Ye ◽  
Yinlun Weng ◽  
Shijie Sun ◽  
Wei Chen ◽  
Xiaobo Wu ◽  
...  

2018 ◽  
Vol 6 (1) ◽  
pp. 30-39
Author(s):  
Hidemitsu Miyatake ◽  
Kazunori Fujino ◽  
Sachiko Tanaka ◽  
Yasuyuki Tsujita ◽  
Minoru Horie ◽  
...  

2015 ◽  
Vol 68 (2) ◽  
pp. 155-157
Author(s):  
José C. Sánchez-Salado ◽  
Albert Ariza-Solé ◽  
Victòria Lorente-Tordera ◽  
Remedios Sánchez-Prieto ◽  
Guillem Muntané-Carol ◽  
...  

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