Synthesis, crystal structure and spectroscopy of bioactive Cd(II) polymeric complex of the non-steroidal anti-inflammatory drug diclofenac sodium: Antiproliferative and biological activity

2015 ◽  
Vol 136 ◽  
pp. 429-436 ◽  
Author(s):  
Leila Tabrizi ◽  
Hossein Chiniforoshan ◽  
Patrick McArdle
Keyword(s):  
Crystal Structure ◽  
Biological Activity ◽  
Diclofenac Sodium ◽  
Polymeric Complex ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals Crystal structure of a mixed-ligand silver(I) complex of the non-steroidal anti-inflammatory drug diclofenac and pyrimidine

2016 ◽  
Vol 72 (10) ◽  
pp. 1475-1479 ◽  
Author(s):  
Sevim Hamamci Alisir ◽  
Necmi Dege
Keyword(s):  
Crystal Structure ◽  
Three Dimensional ◽  
Polymer Structure ◽  
Mixed Ligand ◽  
Dimensional Structure ◽  
Two Dimensional ◽  
Polymeric Complex ◽  
Inflammatory Drug ◽  
Hydrogen Bonding Interactions ◽  
Anti Inflammatory

In the title mixed-ligand silver(I) coordination polymeric complex with the non-steroidal anti-inflammatory drug diclofenac (C14H11Cl2NO2) (diclH) and pyrimidine (pym), namely poly[{μ2-2-[2-(2,6-dichloroanilino)phenyl]acetato-κ2O:O′}(μ2-pyrimidine-κ2N1:N3)silver(I)], [Ag(C14H10Cl2NO2)(C4H4N2)]nor [Ag(μ-dicl)(μ-pym)]n, the very distorted tetrahedral AgN2O2coordination centres comprise two N-atom donors from bridging pym ligands [Ag—N = 2.381 (3) and 2.412 (3) Å] and two carboxylate O-atom donors from dicl ligands [Ag—O = 2.279 (2) and 2.280 (2) Å], which bridge Ag atoms, giving a centrosymmetric dinuclear units with a short Ag...Ag separation [2.8931 (5) Å]. Within the units are short intraligand C—Cl...π(pym) interactions [3.6409 (15) Å]. The units are linked through the bridging N atoms of the pym ligand into a two-dimensional sheet–polymer structure lying parallel to (100) and stabilized by inter-ring π–π interactions between the pym ligands [Cg...Cg= 3.4199 (17) Å]. Additional inter-unit C—H...O and C—H...Cghydrogen-bonding interactions between the sheets give an overall three-dimensional structure.

The effects of the nonsteroidal anti-inflammatory drug diclofenac sodium on the rat kidney, and alteration by furosemide

2008 ◽  
Vol 41 (4) ◽  
pp. 919-926 ◽  
Author(s):  
Ayberk Besen ◽  
Fatih Kose ◽  
Saime Paydas ◽  
Gulfiliz Gonlusen ◽  
Tamer Inal ◽  
...  
Keyword(s):  
Rat Kidney ◽  
Diclofenac Sodium ◽  
Inflammatory Drug ◽  
Anti Inflammatory

scholarly journals A Case Report of Multiple Perforations of Transverse Colon Induced by a Non-steroidal Anti-inflammatory Drug (Diclofenac Sodium)

2004 ◽  
Vol 37 (9) ◽  
pp. 1582-1587 ◽  
Author(s):  
Koichiro Sato ◽  
Junji Sagawa ◽  
Ryo Ichinohasama ◽  
Hiroyuki Kumamoto ◽  
Masato Yamaguchi
Keyword(s):  
Case Report ◽  
Transverse Colon ◽  
Diclofenac Sodium ◽  
Inflammatory Drug ◽  
Anti Inflammatory

Potential management of resistant microbial infections with a novel non-antibiotic: the anti-inflammatory drug diclofenac sodium

2007 ◽  
Vol 30 (3) ◽  
pp. 242-249 ◽  
Author(s):  
Noton Kumar Dutta ◽  
Subramanian Annadurai ◽  
Kaushiki Mazumdar ◽  
Sujata G. Dastidar ◽  
Jette E. Kristiansen ◽  
...  
Keyword(s):  
Diclofenac Sodium ◽  
Inflammatory Drug ◽  
Microbial Infections ◽  
Anti Inflammatory

Hydrate modifications of the non-steroidal anti-inflammatory drug diclofenac sodium: Solid-state characterisation of a trihydrate form

2007 ◽  
Vol 45 (3) ◽  
pp. 443-449 ◽  
Author(s):  
Monica Bartolomei ◽  
Andrea Rodomonte ◽  
Eleonora Antoniella ◽  
Giuliano Minelli ◽  
Paola Bertocchi
Keyword(s):  
Solid State ◽  
Diclofenac Sodium ◽  
Inflammatory Drug ◽  
Anti Inflammatory
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