Treatment of severe and fulminant colitis

2022 ◽  
pp. 100864
Author(s):  
Dominic Vitello ◽  
Michael F. McGee
Keyword(s):  
Fulminant Colitis

Fulminant colitis from Clostridium difficile infection, the epidemic strain ribotype 027, in Japan

2014 ◽  
Vol 20 (6) ◽  
pp. 380-383 ◽  
Author(s):  
Itaru Nakamura ◽  
Tetsuo Yamaguchi ◽  
Ayaka Tsukimori ◽  
Akihiro Sato ◽  
Shinji Fukushima ◽  
...  
Keyword(s):  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Epidemic Strain ◽  
Fulminant Colitis ◽  
Ribotype 027

scholarly journals Emergency subtotal colectomy for fulminant Clostridium difficile colitis – is a surgical solution considered for all patients?

2010 ◽  
Vol 92 (1) ◽  
pp. 56-60 ◽  
Author(s):  
K Gash ◽  
E Brown ◽  
A Pullyblank
Keyword(s):  
Clostridium Difficile ◽  
Subtotal Colectomy ◽  
Postoperative Mortality ◽  
Antibiotic Use ◽  
Morbidity And Mortality ◽  
Fulminant Colitis ◽  
Surgical Morbidity ◽  
Predisposing Factor ◽  
Number Of Patients ◽  
Neurosurgical Patients

INTRODUCTION Clostridium difficile has been an increasing problem in UK hospitals. At the time of this study, there was a high incidence of C. difficile within our trust and a number of patients developed acute fulminant colitis requiring subtotal colectomy. We review a series of colectomies for C. difficile, examining the associated morbidity and mortality and the factors that predispose to acute fulminant colitis. PATIENTS AND METHODS This is a retrospective study of patients undergoing subtotal colectomy for C. difficile colitis in an NHS trust over 18 months. Case notes were reviewed for antibiotic use, duration of diarrhoea, treatment, blood results, pre-operative imaging and surgical morbidity and mortality. RESULTS A total of 1398 patients tested positive for C. difficile in this period. Of these, 18 (1.29%) underwent colectomy. All were emergency admissions, 35% medical, 35% surgical, 24% neurosurgical and 6% orthopaedic. In the cohort, 29% were aged less than 65 years. Patients had a median of three antibiotics (range, 1–6), for a median of 10 days (range, 0–59 days). Median length of stay prior to C. difficile diagnosis was 13 days. Subtotal colectomy was performed a median of 4 days (range, 0–23 days) after diagnosis. Postoperative mortality was 53% (9 of 17). The median C-reactive protein level for those who died was 302 mg/l, in contrast to 214 mg/l in the survival group. Whilst 62% of all C. difficile cases were medical, the colectomy rate was only 0.7%. In the surgical specialties, the colectomy rates were 3.2% for general surgical, 1.2% for orthopaedic and 8% for neurosurgical patients. CONCLUSIONS Colectomy for C. difficile colitis has a high mortality but can be life-saving, even in extremely sick patients. Although heavy antibiotic use is a predisposing factor, this is not an obligatory prerequisite in the development of C. difficile. Neither is it a disease of the elderly, making it difficult to predict vulnerable patients. There are large differences in colectomy rates between specialties and we suggest there may be a place for a surgical opinion in all cases of severe C. difficile colitis.

scholarly journals Fulminant amoebic colitis in the era of computed tomography scan: A case report and review of the literature

2018 ◽  
Vol 22 (1) ◽  
Author(s):  
Suman Mewa Kinoo ◽  
Vikesh V. Ramkelawon ◽  
Jaynund Maharajh ◽  
Bugwan Singh
Keyword(s):  
Computed Tomography ◽  
Bowel Wall ◽  
Abdominal Distension ◽  
Review Of The Literature ◽  
Computed Tomography Scan ◽  
Fulminant Colitis ◽  
Bowel Necrosis ◽  
Amoebic Colitis ◽  
History Of ◽  
Tomography Scan

Amoebic colitis, caused by ingestion of water or food contaminated with the protozoan Entamoeba histolytica, can progress to a fulminant colitis. Computed tomography (CT) findings reported in the literature on this type of colitis are sparse. We present a 59-year-old male patient with a one-week history of progressive abdominal pain, abdominal distension and associated watery and bloody diarrhoea. A CT scan revealed deep ulcerations with submucosal and intramural tracking of contrast. Colonoscopy and biopsy confirmed a diagnosis of Amoebic colitis. The patient required a laparotomy and demised. Deep ulcerations with submucosal and intramural tracking of contrast on CT are diagnostic of fulminant amoebic colitis. Although not demonstrated at CT in this case, discontinuous bowel necrosis, omental wrapping (seen at laparotomy in our case) and neovascularisation of the bowel wall may be other features to look out for.

Acute Cytomegalovirus (CMV) Seroconversion after Blood Transfusion, and Fulminant Colitis

2005 ◽  
Vol 100 ◽  
pp. S227
Author(s):  
Manishkumar Patel ◽  
N. Trigg ◽  
P. Parvathala ◽  
Charles Berkelhammer
Keyword(s):  
Blood Transfusion ◽  
Fulminant Colitis ◽  
Acute Cytomegalovirus

Fulminant Colitis Following Rituximab Therapy for Disseminated B Cell Marginal Lymphoma

2012 ◽  
Vol 107 ◽  
pp. S617
Author(s):  
Seth Lipka ◽  
Rabbi Zia ◽  
James Crawford ◽  
Joseph Ramek ◽  
Navroop Kaur ◽  
...  
Keyword(s):  
B Cell ◽  
Fulminant Colitis

An Unexpected Masquerader: A Case of Acute Fulminant Colitis Secondary to Ulcerative Colitis

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S1649
Author(s):  
Zaid Imam ◽  
Majd Khasawneh ◽  
Ismail Hader
Keyword(s):  
Ulcerative Colitis ◽  
Fulminant Colitis

Fatal Fulminant Colitis Due toSalmonella Saint Paul

1950 ◽  
Vol 20 (2) ◽  
pp. 184-187 ◽  
Author(s):  
Ph. H. Hartz ◽  
A. W. Pot ◽  
O. Felsenfeld
Keyword(s):  
Saint Paul ◽  
Fulminant Colitis

Fulminant colitis

2013 ◽  
Vol 27 (5) ◽  
pp. 771-782 ◽  
Author(s):  
Francisco Portela ◽  
Paula Lago
Keyword(s):  
Fulminant Colitis

Fulminant colitis secondary to nocardiosis

2011 ◽  
Vol 27 (6) ◽  
pp. 841-842 ◽  
Author(s):  
Armin Kamyab ◽  
Joseph D. J. Fakhoury ◽  
Raymond Sutkowski ◽  
Ernesto Drelichman ◽  
Michael J. Jacobs
Keyword(s):  
Fulminant Colitis
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