scholarly journals Lessons learned from bone marrow failure in systemic lupus erythematosus: Case reports and review of the literature

2018 ◽  
Vol 48 (1) ◽  
pp. 90-104 ◽  
Author(s):  
Erik Anderson ◽  
Bhakti Shah ◽  
Anne Davidson ◽  
Richard Furie
Lupus ◽  
2016 ◽  
Vol 25 (14) ◽  
pp. 1509-1519 ◽  
Author(s):  
S Custódio Alves ◽  
S Fasano ◽  
D A Isenberg

The association of systemic lupus erythematosus (SLE) with gastrointestinal autoimmune diseases is rare, but has been described in the literature, mostly as case reports. However, some of these diseases may be very severe, thus a correct and early diagnosis with appropriate management are fundamental. We have analysed our data from the SLE patient cohort at University College Hospital London, established in 1978, identifying those patients with an associated autoimmune gastrointestinal disease. We have also undertaken a review of the literature describing the major autoimmune gastrointestinal pathologies which may be coincident with SLE, focusing on the incidence, clinical and laboratory (particularly antibody) findings, common aetiopathogenesis and complications.


2013 ◽  
Vol 2013 (apr16 1) ◽  
pp. bcr2013008980-bcr2013008980 ◽  
Author(s):  
L. D. Fajardo-Hermosillo ◽  
L. Lopez-Lopez ◽  
A. Nadal ◽  
L. M. Vila

2021 ◽  
Vol 2 (2) ◽  
pp. 96-100
Author(s):  
Döndü Üsküdar Cansu ◽  
Cengiz Korkmaz

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease which may involve several organs or organ systems. SLE may also have hematological as well as joint, kidney, and central nervous system involvements. Hematological abnormalities such as anemia, leukopenia, thrombocytopenia, and autoimmune hemolytic anemia are the best-known and most common hematological findings detected in SLE patients which are included in the classification criteria for SLE.  Autoimmune myelofibrosis (AIMF) refers to bone marrow (BM) fibrosis (myelofibrosis) that develops in an autoimmune setting. Myelofibrosis is not among the SLE classification criteria and it is also not well-known. Current reports in the literature on SLE-associated AIMF are mostly restricted to case reports or reviews of such case reports. The occurrence of BM fibrosis in SLE patients has been explored merely in few studies which concluded that myelofibrosis is a rare symptom of SLE. Herein, we propose the hypothesis that SLE-associated AIMF is not rare and, on the contrary, it can indeed be more frequent than what is known or expected.


2010 ◽  
Vol 128 (4) ◽  
pp. 232-235 ◽  
Author(s):  
Alexandre de Andrade Sousa ◽  
João Marcos Arantes Soares ◽  
Marco Homero de Sá Santos ◽  
Marcelo Portes Rocha Martins ◽  
José Maria Porcaro Salles

CONTEXT: Kikuchi-Fujimoto disease (KFD) manifests in most cases as unilateral cervical lymphadenomegaly, with or without accompanying fever. The disease mainly affects young women and has a self-limited course. It is more common in oriental countries, with few reports of its occurrence in Brazil. KFD should be included in the differential diagnosis of suspected cases of viral infections, tuberculosis, reactive lymphadenitis, systemic lupus erythematosus and metastatic diseases. It can be histologically confused with lymphoma. The disease is benign and self-limiting and an excisional biopsy of an affected lymph node is necessary for diagnosis. There is no specific therapy. CASE REPORTS: This study reports on three cases of non-Asian female patients with KFD who were attended at our service between 2003 and 2006. A review of the literature was carried out, with a systematic search on this topic, with the aim of informing physicians about this entity that is manifested by cervical masses and fever.


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