scholarly journals Processive ubiquitin chain formation by the anaphase-promoting complex

2011 ◽  
Vol 22 (6) ◽  
pp. 544-550 ◽  
Author(s):  
Hermann-Josef Meyer ◽  
Michael Rape
Keyword(s):  
Anaphase Promoting Complex ◽  
Ubiquitin Chain ◽  
Chain Formation

scholarly journals Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex

Cell ◽  
2008 ◽  
Vol 133 (4) ◽  
pp. 653-665 ◽  
Author(s):  
Lingyan Jin ◽  
Adam Williamson ◽  
Sudeep Banerjee ◽  
Isabelle Philipp ◽  
Michael Rape
Keyword(s):  
Anaphase Promoting Complex ◽  
Ubiquitin Chain ◽  
Chain Formation

Hug and hold tight: Dimerization controls the turnover of the ubiquitin-conjugating enzyme UBE2S

2020 ◽  
Vol 13 (654) ◽  
pp. eabd9892
Author(s):  
Anja Bremm
Keyword(s):  
Half Life ◽  
Anaphase Promoting Complex ◽  
Ubiquitin Chain ◽  
Precise Control ◽  
Ubiquitin Conjugating Enzyme ◽  
Conjugating Enzymes ◽  
Chain Synthesis ◽  
Ubiquitin Conjugating Enzymes ◽  
Conjugating Enzyme

Precise control of the activity and abundance of ubiquitin-conjugating enzymes (E2s) ensures fidelity in ubiquitin chain synthesis. In this issue of Science Signaling, Liess et al. demonstrate that the human anaphase-promoting complex (APC/C)–associated E2 UBE2S adopts an autoinhibited dimeric state that increases the half-life of UBE2S by preventing its autoubiquitination-driven turnover.

scholarly journals Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Victoria A. McGuire ◽  
Tamara Ruiz-Zorrilla Diez ◽  
Christoph H. Emmerich ◽  
Sam Strickson ◽  
Maria Stella Ritorto ◽  
...  
Keyword(s):  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Dimethyl Fumarate ◽  
Ubiquitin Chain ◽  
Chain Formation ◽  
Inflammatory Cytokine Production

scholarly journals E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6

2011 ◽  
Vol 108 (14) ◽  
pp. 5590-5595 ◽  
Author(s):  
R. G. Hibbert ◽  
A. Huang ◽  
R. Boelens ◽  
T. K. Sixma
Keyword(s):  
E3 Ligase ◽  
Ubiquitin Chain ◽  
Chain Formation

Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216

2022 ◽  
Author(s):  
Thomas R. Cotton ◽  
Simon A. Cobbold ◽  
Jonathan P. Bernardini ◽  
Lachlan W. Richardson ◽  
Xiangyi S. Wang ◽  
...  
Keyword(s):  
Ubiquitin Ligase ◽  
E3 Ubiquitin Ligase ◽  
Structural Basis ◽  
Ubiquitin Chain ◽  
Chain Formation

scholarly journals Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

2020 ◽  
Author(s):  
Joanna Liwocha ◽  
David T. Krist ◽  
Gerbrand J. van der Heden van Noort ◽  
Fynn M. Hansen ◽  
Vinh H. Truong ◽  
...  
Keyword(s):  
Ubiquitin Chain ◽  
Chain Formation
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