The role of muscarinic and nicotinic receptors in the control of the ovine pyloric antral myoelectric response to nutrients during individual phases of the migrating myoelectric complex

2005 ◽  
Vol 57 (2-3) ◽  
pp. 121-131 ◽  
Author(s):  
K.W. Romański
Keyword(s):  
Nicotinic Receptors ◽  
Migrating Myoelectric Complex ◽  
Muscarinic And Nicotinic Receptors

scholarly journals Designing Hybrids Targeting the Cholinergic System by Modulating the Muscarinic and Nicotinic Receptors: A Concept to Treat Alzheimer’s Disease

Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3230 ◽  
Author(s):  
Daniela Volpato ◽  
Ulrike Holzgrabe
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cholinergic System ◽  
Nicotinic Receptors ◽  
Behavioral Issues ◽  
Bifunctional Compounds ◽  
Molecule Design ◽  
Review Reports ◽  
Muscarinic And Nicotinic Receptors

The cholinergic hypothesis has been reported first being the cause of memory dysfunction in the Alzheimer’s disease. Researchers around the globe have focused their attention on understanding the mechanisms of how this complicated system contributes to processes such as learning, memory, disorientation, linguistic problems, and behavioral issues in the indicated chronic neurodegenerative disease. The present review reports recent updates in hybrid molecule design as a strategy for selectively addressing multiple target proteins involved in Alzheimer’s disease (AD) and the study of their therapeutic relevance. The rationale and the design of the bifunctional compounds will be discussed in order to understand their potential as tools to investigate the role of the cholinergic system in AD.

Reversal of hemorrhagic shock in rats by oxotremorine: the role of muscarinic and nicotinic receptors, and AV3V region

1994 ◽  
Vol 660 (2) ◽  
pp. 261-266 ◽  
Author(s):  
Filiz Onat ◽  
Neslihan Aslan ◽  
Zafer Gören ◽  
Uǧur Özkutlu ◽  
Şule Oktay
Keyword(s):  
Hemorrhagic Shock ◽  
Nicotinic Receptors ◽  
Muscarinic And Nicotinic Receptors

The role of central muscarinic and nicotinic receptors in the regulation of sodium and potassium renal excretion

1976 ◽  
Vol 7 (2-3) ◽  
pp. 145-148 ◽  
Author(s):  
W.A. Saad ◽  
L.A.A. Camargo ◽  
F.G. Graeff ◽  
C.R. Silva-Neto ◽  
J. Antunes-Rodrigues ◽  
...  
Keyword(s):  
Nicotinic Receptors ◽  
Renal Excretion ◽  
Muscarinic And Nicotinic Receptors ◽  
Sodium And Potassium

scholarly journals Cholinergic Signaling, Neural Excitability, and Epilepsy

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2258
Author(s):  
Yu Wang ◽  
Bei Tan ◽  
Yi Wang ◽  
Zhong Chen
Keyword(s):  
Cholinergic Neurons ◽  
Epileptic Seizures ◽  
Brain Disorder ◽  
Neural Excitability ◽  
Cholinergic Signaling ◽  
The Central Nervous System ◽  
Muscarinic And Nicotinic Receptors ◽  
Cumulative Evidence ◽  
Precise Role

Epilepsy is a common brain disorder characterized by recurrent epileptic seizures with neuronal hyperexcitability. Apart from the classical imbalance between excitatory glutamatergic transmission and inhibitory γ-aminobutyric acidergic transmission, cumulative evidence suggest that cholinergic signaling is crucially involved in the modulation of neural excitability and epilepsy. In this review, we briefly describe the distribution of cholinergic neurons, muscarinic, and nicotinic receptors in the central nervous system and their relationship with neural excitability. Then, we summarize the findings from experimental and clinical research on the role of cholinergic signaling in epilepsy. Furthermore, we provide some perspectives on future investigation to reveal the precise role of the cholinergic system in epilepsy.

Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of tropisetron: Role of α7 nicotinic receptors

2006 ◽  
Vol 553 (1-3) ◽  
pp. 191-195 ◽  
Author(s):  
Kenji Hashimoto ◽  
Yuko Fujita ◽  
Tamaki Ishima ◽  
Hiroko Hagiwara ◽  
Masaomi Iyo
Keyword(s):  
Cognitive Deficits ◽  
Nicotinic Receptors
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