Prion protein (PrP) gene polymorphism in Red Maasai and Black Head Persian sheep breeds in Tanzania: Consistent profile regardless of locations

2009 ◽  
Vol 86 (1-3) ◽  
pp. 52-55 ◽  
Author(s):  
M.J. Kipanyula ◽  
I.S. Chuma ◽  
E. Brundtland ◽  
K. Bårdsen ◽  
M.J. Ulvund
Virus Genes ◽  
2012 ◽  
Vol 45 (1) ◽  
pp. 169-175 ◽  
Author(s):  
H. Meydan ◽  
B. Yüceer ◽  
R. Degirmenci ◽  
M. M. Özkan ◽  
M. A. Yildiz

2008 ◽  
Vol 79 (2-3) ◽  
pp. 146-151 ◽  
Author(s):  
M.J. Kipanyula ◽  
I.S. Chuma ◽  
E. Brundtland ◽  
K. Bårdsen ◽  
M.J. Ulvund
Keyword(s):  

2016 ◽  
Vol 40 ◽  
pp. 399-405 ◽  
Author(s):  
Ivan FedIvan GORLOV ◽  
Nadezhda Vasilevna SHIROKOVA ◽  
Alexander Vasilevich RANDELIN ◽  
Valeriya Nikolaevna VORONKOVA ◽  
Natalya Ivanovna MOSOLOVA ◽  
...  

2004 ◽  
Vol 85 (2) ◽  
pp. 547-554 ◽  
Author(s):  
Charalambos Billinis ◽  
Vassilios Psychas ◽  
Leonidas Leontides ◽  
Vassiliki Spyrou ◽  
Stamatis Argyroudis ◽  
...  

A total of 216 local crossbred sheep from 16 scrapie-affected Greek flocks and 210 purebred sheep of the milk breeds Chios and Karagouniko from healthy flocks were analysed for scrapie-linked polymorphisms in the prion protein (PrP) gene. Of the 216 sheep in this case–control study, 96 sheep were clinical cases, 25 subclinical cases (asymptomatic at the moment of euthanasia but positive by histopathology and/or ELISA detecting proteinase-resistant PrP) and 95 healthy controls (negative by all evaluations). Polymorphisms at codons 136, 154 and 171 were determined by denaturing gradient gel electrophoresis, followed by RFLP and sequencing. Scrapie, both clinical and subclinical, was associated with the genotypes ARQ/ARQ (88 of 110 sheep of that genotype), ARQ/TRQ (9 of 13), ARQ/AHQ (15 of 38) and VRQ/VRQ (9 of 17). Histopathological lesions were more severe in the clinical cases. Genotypes ARQ/ARR (26 sheep), ARQ/ARK (seven sheep), AHQ/ARR (one sheep), ARH/ARH (one sheep) and ARR/ARH (three sheep) were detected exclusively in healthy control sheep. In the purebred survey, four genotypes were present in the Chios sheep (ARQ/ARQ, ARQ/TRQ, ARQ/AHQ and ARQ/ARR) and four in the Karagouniko sheep (ARQ/ARQ, ARQ/AHQ, ARQ/ARR and ARQ/ARH).


2009 ◽  
Vol 137 (1-2) ◽  
pp. 18-23 ◽  
Author(s):  
Stefano Pongolini ◽  
Federica Bergamini ◽  
Alessandra Iori ◽  
Sergio Migliore ◽  
Attilio Corradi ◽  
...  
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2006 ◽  
Vol 151 (10) ◽  
pp. 2095-2101 ◽  
Author(s):  
Z. Lan ◽  
Z. L. Wang ◽  
Y. Liu ◽  
X. Zhang

2008 ◽  
Vol 74 (1-3) ◽  
pp. 260-264 ◽  
Author(s):  
C. Ün ◽  
K. Oztabak ◽  
N. Ozdemir ◽  
I. Akıs ◽  
A. Mengi
Keyword(s):  

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