Label free detection of the breast cancer biomarker CA15.3 using ZnO nanorods coated quartz crystal microbalance

2014 ◽  
Vol 195 ◽  
pp. 630-634 ◽  
Author(s):  
Xiaohua Wang ◽  
Huiyao Yu ◽  
Dandan Lu ◽  
Jian Zhang ◽  
Weiwei Deng
Keyword(s):  
Breast Cancer ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Zno Nanorods ◽  
Cancer Biomarker ◽  
Label Free ◽  
Label Free Detection

scholarly journals Magnetic Imprinted Polymer-Based Quartz Crystal Microbalance Sensor for Sensitive Label-Free Detection of Methylene Blue in Groundwater

Sensors ◽  
2020 ◽  
Vol 20 (19) ◽  
pp. 5506
Author(s):  
Yufeng Hu ◽  
Hanwen Xing ◽  
Gang Li ◽  
Minghuo Wu
Keyword(s):  
Methylene Blue ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Sodium Dodecyl ◽  
Sodium Dodecyl Benzene Sulfonate ◽  
Intrinsic Property ◽  
Label Free ◽  
Target Species ◽  
Label Free Detection ◽  
Seawater Samples

Tiny changes in the mass of the sensor in a quartz crystal microbalance with dissipation monitoring (QCM-D) can be observed. However, the lack of specificity for target species has hindered the use of QCM-D. Here, molecularly imprinted polymers (MIPs) were used to modify a QCM-D sensor to provide specificity. The MIPs were formed in the presence of sodium dodecyl benzene sulfonate. Imprinted layers on Fe3O4 nanoparticles were formed using pyrrole as the functional monomer and cross-linker and methylene blue (MB) as a template. The MIPs produced were then attached to the surface of a QCM-D sensor. The MIPs-coated QCM-D sensor could recognize MB and gave a linear response in the concentration range 25 to 1.5 × 102 µg/L and a detection limit of 1.4 µg/L. The QCM-D sensor was selective for MB over structural analogs. The MIPs-coated QCM-D sensor was successfully used to detect MB in river water and seawater samples, and the recoveries were good. This is the first time MB has been detected using a QCM-D sensor. Mass is an intrinsic property of matter, so this method could easily be extended to other target species by using different MIPs.

Label-Free Detection of Gliadin in Food by Quartz Crystal Microbalance-Based Immunosensor

2017 ◽  
Vol 65 (6) ◽  
pp. 1281-1289 ◽  
Author(s):  
Riccardo Funari ◽  
Irma Terracciano ◽  
Bartolomeo Della Ventura ◽  
Sara Ricci ◽  
Teodoro Cardi ◽  
...  
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Label Free ◽  
Label Free Detection
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