Simultaneous determination of ascorbic acid, dopamine and uric acid using poly(l-leucine)/DNA composite film modified electrode

2015 ◽  
Vol 213 ◽  
pp. 188-194 ◽  
Author(s):  
Xinyu Zheng ◽  
Yuheng Guo ◽  
Jinshuai Zheng ◽  
Xuechou Zhou ◽  
Qinglu Li ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Gen Liu ◽  
Wei Ma ◽  
Yan Luo ◽  
Deng-ming Sun ◽  
Shuang Shao

Poly(methylene blue) and electrochemically reduced graphene oxide composite film modified electrode (PMB-ERGO/GCE) was successfully fabricated by electropolymerization and was used for simultaneous determination of uric acid (UA) and xanthine (Xa). Based on the excellent electrocatalytic activity of PMB-ERGO/GCE, the electrochemical behaviors of UA and Xa were studied by cyclic voltammetry (CV) and square wave voltammetry (SWV). Two anodic sensitive peaks at 0.630 V (versus Ag/AgCl) for UA and 1.006 V (versus Ag/AgCl) for Xa were given by CV in pH 3.0 phosphate buffer. The calibration curves for UA and Xa were obtained in the range of 8.00 × 10−8~4.00 × 10−4 M and 1.00 × 10−7~4.00 × 10−4 M, respectively, by SWV. The detection limits for UA and Xa were3.00×10-8 M and5.00×10-8 M, respectively. Finally, the proposed method was applied to simultaneously determine UA and Xa in human urine with good selectivity and high sensitivity.


2020 ◽  
Vol 44 (12) ◽  
pp. 4916-4926 ◽  
Author(s):  
Chaoli Tan ◽  
Jie Zhao ◽  
Peng Sun ◽  
Wei Zheng ◽  
Guofeng Cui

AuNPs, GO and PPy are combined effectively to form a novel composite showing a huge enhancement in electrochemical performance compared to the single materials.


2008 ◽  
Vol 164 (3-4) ◽  
pp. 357-362 ◽  
Author(s):  
Guangfeng Wang ◽  
Jingao Sun ◽  
Wei Zhang ◽  
Shoufeng Jiao ◽  
Bin Fang

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