scholarly journals Nanocomposite-based controlled release formulation of an herbicide, 2,4-dichlorophenoxyacetate incapsulated in zinc–aluminium-layered double hydroxide

2005 ◽  
Vol 6 (8) ◽  
pp. 956-962 ◽  
Author(s):  
Mohd Zobir bin Hussein ◽  
Asmah Hj Yahaya ◽  
Zulkarnain Zainal ◽  
Loo Hee Kian
Author(s):  
Rajesh Dubey ◽  
Udaya K. Chowdary ◽  
Venkateswarlu V.

A controlled release formulation of metoclopramide was developed using a combination of hypromellose (HPMC) and hydrogenated castor oil (HCO). Developed formulations released the drug over 20 hr with release kinetics following Higuchi model. Compared to HCO, HPMC showed significantly higher influence in controlling the drug release at initial as well as later phase. The difference in the influence can be explained by the different swelling and erosion behaviour of the polymers. Effect of the polymers on release was optimized using a face-centered central composite design to generate a predictable design space. Statistical analysis of the drug release at various levels indicated a linear effect of the polymers’ levels on the drug release. The release profile of formulations containing the polymer levels at extremes of their ranges in design space was found to be similar to the predicted release profile


RSC Advances ◽  
2015 ◽  
Vol 5 (53) ◽  
pp. 42666-42680 ◽  
Author(s):  
Ranjith Kumar Kankala ◽  
Yaswanth Kuthati ◽  
Chen-Lun Liu ◽  
Chia-Hung Lee

Inorganic nanostructured ensembles containing an anionic clay matrix with layered double hydroxide (LDH) were designed in nanooncology for photosensitizer delivery.


2017 ◽  
Vol 24 (23) ◽  
pp. 19386-19392 ◽  
Author(s):  
Nguyen Thi Kim Phuong ◽  
Ho Nguyen Nhat Ha ◽  
Nguyen Thi Phuong Dieu ◽  
Bui The Huy

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