scholarly journals Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells

2017 ◽  
Vol 9 (1) ◽  
pp. 108-121 ◽  
Author(s):  
Keriayn N. Smith ◽  
Joshua Starmer ◽  
Sarah C. Miller ◽  
Praveen Sethupathy ◽  
Terry Magnuson
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Embryonic Stem ◽  
Self Renewal

scholarly journals Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

2013 ◽  
Vol 110 (8) ◽  
pp. 2876-2881 ◽  
Author(s):  
A. A. Sigova ◽  
A. C. Mullen ◽  
B. Molinie ◽  
S. Gupta ◽  
D. A. Orlando ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Embryonic Stem ◽  
Gene Pairs ◽  
Mrna Gene ◽  
Divergent Transcription

scholarly journals The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0191682 ◽  
Author(s):  
Maria Winzi ◽  
Nuria Casas Vila ◽  
Maciej Paszkowski-Rogacz ◽  
Li Ding ◽  
Svenja Noack ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Long Noncoding Rna ◽  
Neural Differentiation ◽  
Noncoding Rna ◽  
Embryonic Stem ◽  
Murine Embryonic Stem Cells

scholarly journals DIGIT Is a Conserved Long Noncoding RNA that Regulates GSC Expression to Control Definitive Endoderm Differentiation of Embryonic Stem Cells

Cell Reports ◽  
2016 ◽  
Vol 17 (2) ◽  
pp. 353-365 ◽  
Author(s):  
Kaveh Daneshvar ◽  
Joshua V. Pondick ◽  
Byeong-Moo Kim ◽  
Chan Zhou ◽  
Samuel R. York ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Embryonic Stem ◽  
Definitive Endoderm ◽  
Endoderm Differentiation

scholarly journals A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Ya-Pu Li ◽  
Fei-Fei Duan ◽  
Yu-Ting Zhao ◽  
Kai-Li Gu ◽  
Le-Qi Liao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Embryonic Stem ◽  
Erk Signaling

scholarly journals Discovery of a Novel Long Noncoding RNA Lx8-SINE B2 as a Marker of Pluripotency

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Fuquan Chen ◽  
Miao Zhang ◽  
Xiao Feng ◽  
Xiaomin Li ◽  
Haotian Sun ◽  
...  
Keyword(s):  
Stem Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Embryonic Stem ◽  
Specific Expression ◽  
Self Renewal ◽  
Transcription Regulators ◽  
Full Length Sequence ◽  
Rapid Amplification ◽  
Important Marker

Pluripotency and self-renewal of embryonic stem cells (ESCs) are marked by core transcription regulators such as Oct4, Sox2, and Nanog. Another important marker of pluripotency is the long noncoding RNA (lncRNA). Here, we ind that a novel long noncoding RNA (lncRNA) Lx8-SINE B2 is a marker of pluripotency. LncRNA Lx8-SINE B2 is enriched in ESCs and downregulated during ESC differentiation. By rapid amplification of cDNA ends, we identified the full-length sequence of lncRNA Lx8-SINE B2. We further showed that transposable elements at upstream of lncRNA Lx8-SINE B2 could drive the expression of lncRNA Lx8-SINE B2. Furthermore, ESC-specific expression of lncRNA Lx8-SINE B2 was driven by Oct4 and Sox2. In summary, we identified a novel marker lncRNA of ESCs, which is driven by core pluripotency regulators.

scholarly journals Effects of Ionizing Radiation on Self-Renewal and Pluripotency of Human Embryonic Stem Cells

2010 ◽  
Vol 70 (13) ◽  
pp. 5539-5548 ◽  
Author(s):  
Kitchener D. Wilson ◽  
Ning Sun ◽  
Mei Huang ◽  
Wendy Y. Zhang ◽  
Andrew S. Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Ionizing Radiation ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Self Renewal
Sign in / Sign up

Export Citation Format

Share Document