Supercritical fluid simulated moving bed chromatography for the separation of ethyl linoleate and ethyl oleate

2012 ◽  
Vol 66 ◽  
pp. 129-136 ◽  
Author(s):  
Carlos Andrés Martínez Cristancho ◽  
Stephanie Peper ◽  
Monika Johannsen
Keyword(s):  
Supercritical Fluid ◽  
Ethyl Oleate ◽  
Ethyl Linoleate ◽  
Simulated Moving Bed ◽  
Moving Bed ◽  
Simulated Moving Bed Chromatography

Enantioseparation of 1-phenyl-1-propanol by supercritical fluid-simulated moving bed chromatography

2005 ◽  
Vol 1092 (1) ◽  
pp. 55-64 ◽  
Author(s):  
Arvind Rajendran ◽  
Stephanie Peper ◽  
Monika Johannsen ◽  
Marco Mazzotti ◽  
Massimo Morbidelli ◽  
...  
Keyword(s):  
Supercritical Fluid ◽  
Simulated Moving Bed ◽  
Moving Bed ◽  
Simulated Moving Bed Chromatography

Supercritical fluid simulated moving bed chromatography

1997 ◽  
Vol 786 (2) ◽  
pp. 309-320 ◽  
Author(s):  
Marco Mazzotti ◽  
Giuseppe Storti ◽  
Massimo Morbidelli
Keyword(s):  
Supercritical Fluid ◽  
Simulated Moving Bed ◽  
Moving Bed ◽  
Simulated Moving Bed Chromatography

Supercritical fluid simulated moving bed chromatography

2001 ◽  
Vol 919 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Orazio Di Giovanni ◽  
Marco Mazzotti ◽  
Massimo Morbidelli ◽  
Félicie Denet ◽  
Willy Hauck ◽  
...  
Keyword(s):  
Supercritical Fluid ◽  
Simulated Moving Bed ◽  
Moving Bed ◽  
Simulated Moving Bed Chromatography

scholarly journals Progress in the Enantioseparation of β-Blockers by Chromatographic Methods

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 468
Author(s):  
Yiwen Yang ◽  
Yehui Wang ◽  
Zongbi Bao ◽  
Qiwei Yang ◽  
Zhiguo Zhang ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
High Performance ◽  
Simulated Moving Bed ◽  
Moving Bed ◽  
Chromatographic Methods ◽  
Simulated Moving Bed Chromatography ◽  
Β Blockers

β-adrenergic antagonists (β-blockers) with at least one chiral center are an exceedingly important class of drugs used mostly to treat cardiovascular diseases. At least 70 β-blockers have been investigated in history. However, only a few β-blockers, e.g., timolol, are clinically marketed as an optically pure enantiomer. Therefore, the separation of racemates of β-blockers is essential both in the laboratory and industry. Many approaches have been explored to obtain the single enantiomeric β-blocker, including high performance liquid chromatography, supercritical fluid chromatography and simulated moving bed chromatography. In this article, a review is presented on different chromatographic methods applied for the enantioseparation of β-blockers, covering high performance liquid chromatography (HPLC), supercritical fluid chromatography (SFC) and simulated moving bed chromatography (SMB).

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