Thirty-day mortality leads to underestimation of postoperative death after liver resection: A novel method to define the acute postoperative period

Surgery ◽  
2015 ◽  
Vol 158 (6) ◽  
pp. 1530-1537 ◽  
Author(s):  
Tobias S. Schiergens ◽  
Maximilian Dörsch ◽  
Laura Mittermeier ◽  
Katharina Brand ◽  
Helmut Küchenhoff ◽  
...  
Keyword(s):  
Liver Resection ◽  
Postoperative Period ◽  
Postoperative Death ◽  
Novel Method

A novel method using the VIO soft-coagulation system for liver resection

Surgery ◽  
2011 ◽  
Vol 149 (3) ◽  
pp. 438-444 ◽  
Author(s):  
Fumitoshi Hirokawa ◽  
Michihiro Hayashi ◽  
Yoshiharu Miyamoto ◽  
Mitsuhiko Iwamoto ◽  
Ichiro Tsunematsu ◽  
...  
Keyword(s):  
Liver Resection ◽  
Coagulation System ◽  
Soft Coagulation ◽  
Novel Method

scholarly journals EFFECT OF SINGLE INTAKE OF EXOGENOUS HEPATOCYTES GROWTH INDUCER ON THE INDICES OF NON-SPECIFIC RESISTANCE UNDER CONDITIONS OF POSTRESECTION LIVER INJURY

2016 ◽  
Vol 1 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Прокопьев ◽  
Maksim Prokopev ◽  
Коваль ◽  
Elena Koval ◽  
Курганский ◽  
...  
Keyword(s):  
Immune Response ◽  
Liver Resection ◽  
Liver Injury ◽  
Inflammatory Response ◽  
Postoperative Period ◽  
Wistar Rats ◽  
Specific Resistance ◽  
White Male ◽  
Early Postoperative Period ◽  
Male Wistar Rats

HGF is one of the factors taking part in regeneration and recovery of liver after injury. The article is dedicated to the study of influence of single HGF intake on the indices of non-specific immune response in rats after 70% liver resection in the early postoperative period. Research was conducted on 42 six-months white male Wistar rats of 250–300 g. It was revealed that level of segmentonuclear neutrophils and lymphocytes in the group with HGF intake stand at normal level on the 2nd day and normalizes to the 11th day that testifies to the decrease of inflammatory response. Increased level of leukocytes and monocytes is registered in the group with HGF intake. Also integrity of non-specific resistance in the early postoperative period on the 2nd day is registered. Suppression of phagocytosis indices with preservation of functional activity of phagocytes was registered to the 11th day.

scholarly journals Surglcel ® Reinforced Resection Lines in Left-sided Hepatectomy with Linear Stapling Device. An Experimental Study on Pigs

HPB Surgery ◽  
1996 ◽  
Vol 9 (2) ◽  
pp. 97-99
Author(s):  
Thomas Zilling ◽  
Torsten Holmin
Keyword(s):  
Experimental Study ◽  
Liver Resection ◽  
High Frequency ◽  
Clinical Situation ◽  
Median Number ◽  
The Other ◽  
Postoperative Death ◽  
Stapling Device ◽  
Time Required ◽  
Postoperative Haemoglobin

Fourteen pigs underwent left-sided hepatectomy. The resection was performed with a linear stapling device and the pigs were randomised to either Surgicel ® reinforced resection lines or not. The median time required for resection was 25 min (range 17-30) in the Surgicel® reinforced group compared to 30 min (range 21-41) in the stapled group. This difference was, however, not statistically significant (p=0.053).The postoperative haemoglobin value was lower in the stapled group compared to the Surgicel® reinforced group 69 g/1 (range 42-85) versus 82 g/1 (range 78-90) (p=0.018). The estimated blood losses by weighing the compresses were 287 ml (range 166-379) for the stapled group and 204 ml (range 152-264) for the Surgicel® reinforced group (p=0.053). The median number of additional haemostatic sutures in the Surgicel® reinforced group was 7 (range 3-11) and in the stapled group 10 (range 5-15) (p=0.038).The haemoglobin value was similar in the two groups week postoperatively; 100 g/1 (range 87-104) and 102 g/1 (range 95-114), p=0.27, in the stapled group and the Surgicel® reinforced group, respectively. In the stapled group reinforced with the Surgicel® there was one postoperative death. In the solely stapled group there was no postoperative death (p=0.5). Four out of six pigs in the Surgicel® group had massive adhesions to the resection lines. One of these six pigs was sacrificed postoperatively as it was ill and had small bowel obstruction secondary to Surgicel® induced adhesions. On the other hand, no adhesions were seen in the solely stapled pigs (p=0.09). At this point, we can not recommend the use of Surgicel® to reinforce resection lines at stapled liver resection in the clinical situation, because of the high frequency of adhesions this material creates.

Open versus laparoscopic liver resection: looking beyond the immediate postoperative period

2011 ◽  
Vol 26 (2) ◽  
pp. 468-472 ◽  
Author(s):  
Joshua D. Gustafson ◽  
Justin P. Fox ◽  
James R. Ouellette ◽  
Minia Hellan ◽  
Paula Termuhlen ◽  
...  
Keyword(s):  
Liver Resection ◽  
Postoperative Period ◽  
Laparoscopic Liver Resection ◽  
Open Versus

Elective resection of the liver: nursing care

1989 ◽  
Vol 9 (10) ◽  
pp. 40-49 ◽  
Author(s):  
S Beckermann ◽  
S Galloway
Keyword(s):  
Liver Resection ◽  
Surgical Resection ◽  
Nursing Care ◽  
Postoperative Period ◽  
Preoperative Period ◽  
Elective Resection ◽  
Anatomy And Physiology ◽  
Liver Resections ◽  
Resection Of The Liver ◽  
Psychologic Responses

Until recently, surgical resection of the liver was done mainly for benign or traumatic conditions. Liver resections are now an accepted treatment for primary and some metastatic cancers of the liver. Nurses play an important role in the management of all liver resection patients and need to have an understanding of the anatomy and physiology of the liver, the tests performed during the preoperative period, the surgery performed, and the physiologic and psychologic responses of the patients during the postoperative period.

scholarly journals The role of free radical oxidation in damage of the stomach and duodenum after limiting resection of the liver (experimental study)

2020 ◽  
pp. 31-37
Author(s):  
Л.О. Барская ◽  
Т.П. Храмых ◽  
П.А. Ермолаев ◽  
С.В. Пальянов
Keyword(s):  
Free Radical ◽  
Liver Resection ◽  
Postoperative Period ◽  
Structural Changes ◽  
Histological Study ◽  
Free Radical Oxidation ◽  
Early Postoperative Period ◽  
Male Rats ◽  
Control Group ◽  
Radical Oxidation

Предельно допустимые резекции печени являются операциями выбора у пациентов с очаговыми образованиями, при этом остается актуальной проблема язвенных желудочно-кишечных кровотечений после таких операций. В условиях периоперационного стресса активируются процессы свободнорадикального окисления, что оказывает повреждающий эффект на органы и ткани организма. Поэтому целью нашего исследования стала оценка параметров свободнорадикального окисления в желудке и двенадцатиперстной кишке в раннем послеоперационном периоде после предельно допустимой резекции печени с определением срока начальных изменений в этих органах. Методика. Исследование было выполнено на 70 белых беспородных крысах-самцах массой 200-230 г. Резекцию печени по оригинальной методике выполняли 60 животным, 10 интактных крыс составляли группу контроля. Через 6 часов, 12 часов, 1, 3, 7 и 30 суток извлекали желудок и двенадцатиперстную кишку для исследования хемилюминесценции гомогенатов, а также готовили гистологические препараты. Полученные результаты свидетельствуют о том, что активация процессов свободнорадикального окисления происходит уже через 12 часов после операции, при этом пик изменений приходится на срок 12 часов в двенадцатиперстной кишке, и на 1 сутки - в желудке. Структурные изменения в этих органах наблюдаются через 12 часов и проявляются формированием эрозий и язв. В желудке эти изменения необратимы, поскольку замещаются рубцом, а в двенадцатиперстной кишке обратимы, так как в позднем послеоперационном периоде замещаются практически зрелым эпителием. Maximum allowable liver resections are the operation of choice for patients with focal formations while the problem of ulcerative gastrointestinal bleeding after such operations remains relevant. Under the conditions of perioperative stress, free radical oxidation processes are activated and exert a detrimental effect on organs and tissues. Therefore, the aim of our study was to evaluate parameters of free radical oxidation in the stomach and duodenum in the early postoperative period after the maximum allowable liver resection and to determine the time of initial changes in these organs. The study was performed on 70 white outbred male rats weighing 200-230 g. Liver resection was performed according to the original method in 60 rats; the control group consisted of 10 intact rats. After 6, 12 h, 1, 3, 7, and 30 days, the stomach and duodenum were excised for a chemiluminescence study of homogenates and a histological study of preparations. Results of the study showed that the activation of free radical oxidation occurred already at 12 h after the surgery. The peak changes occurred at 12 h in the duodenum and at 24 h in the stomach. Structural changes in these organs were observed at 12 h and were evident as erosions and ulcers. In the stomach, these changes were irreversible, since they were replaced with a scar whereas in the duodenum, they were reversible, since they were replaced with almost mature epithelium in the late postoperative period.

The removal and morphology of intact biofilms from implanted venous access devices

1995 ◽  
Vol 53 ◽  
pp. 1020-1021
Author(s):  
M.A. Gregory ◽  
G.P. Hadley
Keyword(s):  
Patient Selection ◽  
Surgical Oncology ◽  
Venous Access ◽  
Common Procedure ◽  
Indwelling Catheters ◽  
Careful Patient ◽  
Novel Method ◽  
The Subject ◽  
Vascular Catheters ◽  
Venous Access Devices

The insertion of implanted venous access systems for children undergoing prolonged courses of chemotherapy has become a common procedure in pediatric surgical oncology. While not permanently implanted, the devices are expected to remain functional until cure of the primary disease is assured. Despite careful patient selection and standardised insertion and access techniques, some devices fail. The most commonly encountered problems are colonisation of the device with bacteria and catheter occlusion. Both of these difficulties relate to the development of a biofilm within the port and catheter. The morphology and evolution of biofilms in indwelling vascular catheters is the subject of ongoing investigation. To date, however, such investigations have been confined to the examination of fragments of biofilm scraped or sonicated from sections of catheter. This report describes a novel method for the extraction of intact biofilms from indwelling catheters.15 children with Wilm’s tumour and who had received venous implants were studied. Catheters were removed because of infection (n=6) or electively at the end of chemotherapy.

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