Metabolic syndrome predicts worse perioperative outcomes in patients treated with radical prostatectomy for non-metastatic prostate cancer

2021 ◽  
Author(s):  
Stefano Luzzago ◽  
Carlotta Palumbo ◽  
Giuseppe Rosiello ◽  
Angela Pecoraro ◽  
Marina Deuker ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Metabolic Syndrome ◽  
Radical Prostatectomy ◽  
Metastatic Prostate Cancer ◽  
Perioperative Outcomes

scholarly journals A Multi-institutional Analysis of Perioperative Outcomes in 106 Men Who Underwent Radical Prostatectomy for Distant Metastatic Prostate Cancer at Presentation

2016 ◽  
Vol 69 (5) ◽  
pp. 788-794 ◽  
Author(s):  
Prasanna Sooriakumaran ◽  
Jeffrey Karnes ◽  
Christian Stief ◽  
Bethan Copsey ◽  
Francesco Montorsi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Metastatic Prostate Cancer ◽  
Institutional Analysis ◽  
Perioperative Outcomes

646: 25-Year Outcomes of Radical Prostatectomy for the Treatment of All Stages of Non-Metastatic Prostate Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 208-208
Author(s):  
Brant A. Inman ◽  
Jeffrey M. Slezak ◽  
Eugene D. Kwon ◽  
Robert P. Myers ◽  
Bradley C. Leibovich ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Metastatic Prostate Cancer

scholarly journals Radical Prostatectomy or External Beam Radiation Therapy vs No Local Therapy for Survival Benefit in Metastatic Prostate Cancer: A SEER-Medicare Analysis

2015 ◽  
Vol 194 (2) ◽  
pp. 378-385 ◽  
Author(s):  
Raj Satkunasivam ◽  
Andre E. Kim ◽  
Mihir Desai ◽  
Mike M. Nguyen ◽  
David I. Quinn ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radiation Therapy ◽  
Radical Prostatectomy ◽  
Survival Benefit ◽  
Metastatic Prostate Cancer ◽  
Local Therapy ◽  
External Beam Radiation Therapy ◽  
External Beam Radiation ◽  
External Beam ◽  
Beam Radiation

Inductive androgen deprivation and radical prostatectomy in T4 prostate cancer: Consecutive assessment of perioperative outcomes and long-term follow up

2019 ◽  
Vol 18 (1) ◽  
pp. e299-e300
Author(s):  
M. Saar ◽  
C. Niklas ◽  
T. Hajili ◽  
C-H. Ohlmann ◽  
J. Linxweiler ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Androgen Deprivation ◽  
Perioperative Outcomes ◽  
Long Term Follow Up

867 EFFECTS OF METABOLIC SYNDROME ON PSA CONCENTRATIONS IN METASTATIC PROSTATE CANCER TREATED WITH COMBINED ANDROGEN BLOCKADE

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Kyung Seo Park ◽  
Kwan Joong Joo ◽  
Young Sam Cho ◽  
Heung Jae Park ◽  
Chil Hun Kwon
Keyword(s):  
Prostate Cancer ◽  
Metabolic Syndrome ◽  
Metastatic Prostate Cancer ◽  
Combined Androgen Blockade ◽  
Androgen Blockade

scholarly journals The role of radical prostatectomy for the treatment of metastatic prostate cancer: a systematic review and meta-analysis

2018 ◽  
Vol 38 (1) ◽  
Author(s):  
Yi Wang ◽  
Zhiqiang Qin ◽  
Yamin Wang ◽  
Chen Chen ◽  
Yichun Wang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Gleason Score ◽  
Metastatic Prostate Cancer ◽  
Meta Analysis ◽  
Local Therapy ◽  
Quality Data ◽  
N Stage ◽  
High Level

The recommended therapy by EAU guidelines for metastatic prostate cancer (mPCa) is androgen deprivation therapy (ADT) with or without chemotherapy. The role of radical prostatectomy (RP) in the treatment of mPCa is still controversial. Hence, a meta-analysis was conducted by comprehensively searching the databases PubMed, EMBASE and Web of Science for the relevant studies published before September 1st, 2017. Our results successfully shed light on the relationship that RP for mPCa was associated with decreased cancer-specific mortality (CSM) (pooled HR = 0.41, 95%CI = 0.36–0.47) and enhanced overall survival (OS) (pooled HR = 0.49, 95%CI = 0.44–0.55). Subsequent stratified analysis demonstrated that no matter how RP compared with no local therapy (NLT) or radiation therapy (RT), it was linked to a lower CSM (pooled HR = 0.36, 95%CI = 0.30–0.43 and pooled HR = 0.56, 95%CI 0.43–0.73, respectively) and a higher OS (pooled HR = 0.49, 95%CI = 0.44–0.56 and pooled HR = 0.46, 95%CI 0.33–0.65, separately). When comparing different levels of Gleason score, M-stage or N-stage, our results indicated that high level of Gleason score, M-stage or N-stage was associated with increased CSM. In summary, the outcomes of the present meta-analysis demonstrated that RP for mPCa was correlated with decreased CSM and enhanced OS in eligible patients of involved studies. In addition, patients with less aggressive tumors and good general health seemed to benefit the most. Moreover, no matter compared with NLT or RT, RP showed significant superiority in OS or CSM. Upcoming prospective randomized controlled trials were warranted to provide more high-quality data.

Contemporary Trends and Survival Outcomes After Aborted Radical Prostatectomy in Lymph Node Metastatic Prostate Cancer Patients

2019 ◽  
Vol 5 (3) ◽  
pp. 381-388 ◽  
Author(s):  
Marco Bandini ◽  
Felix Preisser ◽  
Sebastiano Nazzani ◽  
Michele Marchioni ◽  
Zhe Tian ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Radical Prostatectomy ◽  
Cancer Patients ◽  
Metastatic Prostate Cancer ◽  
Survival Outcomes

scholarly journals Focal therapy compared to radical prostatectomy for non-metastatic prostate cancer: A propensity matched study

2020 ◽  
Vol 19 ◽  
pp. e1351-e1352
Author(s):  
D.T. Reddy ◽  
T.T. Shah ◽  
M. Peters ◽  
E. Gomez-Gomez ◽  
S. Guillaumier ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Metastatic Prostate Cancer ◽  
Focal Therapy ◽  
Matched Study
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