The diagnostic value of thyroglobulin in fine-needle aspiration of metastatic lymph nodes in patients with papillary thyroid cancer and its influential factors

2021 ◽  
pp. 101666
Author(s):  
Yuxuan Wang ◽  
Yuansheng Duan ◽  
Mengqian Zhou ◽  
Jin Liu ◽  
Qingchuan Lai ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Fine Needle Aspiration ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Influential Factors ◽  
Papillary Thyroid ◽  
Fine Needle ◽  
Metastatic Lymph Nodes

scholarly journals Diagnostic value of fine needle aspiration BRAFV600E mutation analysis in papillary thyroid cancer: a systematic review and meta-analysis

2015 ◽  
Vol 46 (10) ◽  
pp. 1443-1454 ◽  
Author(s):  
Naif Fnais ◽  
Charlene Soobiah ◽  
Khalid AL-Qahtani ◽  
Jemila S. Hamid ◽  
Laure Perrier ◽  
...  
Keyword(s):  
Systematic Review ◽  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Fine Needle Aspiration ◽  
Meta Analysis ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Papillary Thyroid ◽  
Brafv600e Mutation ◽  
Fine Needle

Lymph node fine-needle aspiration washout thyroglobulin in papillary thyroid cancer: Diagnostic value and the effect of thyroglobulin antibodies

2016 ◽  
Vol 41 (4) ◽  
pp. 281-289 ◽  
Author(s):  
Ceyla Konca Degertekin ◽  
Mehmet Muhittin Yalcin ◽  
Turgay Cerit ◽  
Cigdem Ozkan ◽  
Isilay Kalan ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Papillary Thyroid Cancer ◽  
Fine Needle Aspiration ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Papillary Thyroid ◽  
Thyroglobulin Antibodies ◽  
Fine Needle ◽  
Cancer Diagnostic

scholarly journals Thyroglobulin measurements in washout of fine needle aspirates in cervical lymph nodes for detection of papillary thyroid cancer metastases

2010 ◽  
Vol 54 (6) ◽  
pp. 550-554 ◽  
Author(s):  
André B. Zanella ◽  
Erika L. Souza Meyer ◽  
Letícia Balzan ◽  
Antônio C. Silva ◽  
Joíza Camargo ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Needle Aspiration ◽  
Papillary Thyroid ◽  
Cervical Lymph Nodes ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Cancer Metastases ◽  
Thyroid Cancer Metastases

OBJECTIVE: The aim of this study was to evaluate the accuracy of the measurement of thyroglobulin in washout needle aspiration biopsy (FNAB-Tg) to detect papillary thyroid cancer (PTC) metastases. SUBJECTS AND METHODS: Forty-three patients (51.4 ± 14.6 years) with PTC diagnosis and evidence of enlarged cervical lymph nodes (LN) were included. An ultrasound-guided fine-needle aspiration of suspicious LN was performed, for both cytological examination and measurement of FNAB-Tg. RESULTS: The median values of FNAB-Tg in patients with metastatic LN (n = 5) was 3,419 ng/mL (11.1-25,538), while patients without LN metastasis (n = 38) showed levels of 3.7 ng/mL (0.8-7.4). Considering a 10 ng/mL cutoff value for FNAB-Tg, the sensitivity and specificity was 100%. There were no differences on the median of FNAB-Tg measurements between those on (TSH 0.07 mUI/mL) or off levothyroxine (TSH 97.4 mUI/mL) therapy (3.3 vs. 3.8 ng/mL, respectively; P = 0.2). CONCLUSION: The results show that evaluation of FNAB-Tg in cervical LN is a valuable diagnostic tool for PTC metastases that can be used independent of the thyroid status.

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